Detail

UniProtKB-Q13563


Protein	Polycystin-2
Gene	PKD2
Status	Reviewed
Source	Breast cancer xenografts; DLBCL cell lines (Diffuse large B-cell lymphoma); Liver; OVCAR-3 cell line (Ovarian cancer); Pancreatic islets; Plasma; Prostate; Prostate tumor; SKOV-3 cell line (Ovarian cancer); Serum
Years	2007-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
299	MQPSnQTEADNR	2012(48); 2013(34); 2013(34); 2014(16);
305	MQPSNQTEADnR	2012(48); 2013(34); 2013(34); 2014(16);
328	nGSCSIPQDLR	2015(unpublished);
328	VRnGSCSIPQDLRDEIK	2009(66); 2010(40);
362	nGTAWIYTSEK	2014(14);
375	TSEKDLnGSSHW	2014(33);
375	IYTSEKDLnGSSHW	2014(33);
961	EGAGGnGSSNVH	2007(unpublished);

Sequence

1	11	21	31	41	51	61	71	81	91
MVNSSRVQPQ	QPGDAKRPPA	PRAPDPGRLM	AGCAAVGASL	AAPGGLCEQR	GLEIEMQRIR	QAAARDPPAG	AAASPSPPLS	SCSRQAWSRD	NPGFEAEEEE
101	111	121	131	141	151	161	171	181	191
EEVEGEEGGM	VVEMDVEWRP	GSRRSAASSA	VSSVGARSRG	LGGYHGAGHP	SGRRRRREDQ	GPPCPSPVGG	GDPLHRHLPL	EGQPPRVAWA	ERLVRGLRGL
201	211	221	231	241	251	261	271	281	291
WGTRLMEESS	TNREKYLKSV	LRELVTYLLF	LIVLCILTYG	MMSSNVYYYT	RMMSQLFLDT	PVSKTEKTNF	KTLSSMEDFW	KFTEGSLLDG	LYWKMQPSNQ
301	311	321	331	341	351	361	371	381	391
TEADNRSFIF	YENLLLGVPR	IRQLRVRNGS	CSIPQDLRDE	IKECYDVYSV	SSEDRAPFGP	RNGTAWIYTS	EKDLNGSSHW	GIIATYSGAG	YYLDLSRTRE
401	411	421	431	441	451	461	471	481	491
ETAAQVASLK	KNVWLDRGTR	ATFIDFSVYN	ANINLFCVVR	LLVEFPATGG	VIPSWQFQPL	KLIRYVTTFD	FFLAACEIIF	CFFIFYYVVE	EILEIRIHKL
501	511	521	531	541	551	561	571	581	591
HYFRSFWNCL	DVVIVVLSVV	AIGINIYRTS	NVEVLLQFLE	DQNTFPNFEH	LAYWQIQFNN	IAAVTVFFVW	IKLFKFINFN	RTMSQLSTTM	SRCAKDLFGF
601	611	621	631	641	651	661	671	681	691
AIMFFIIFLA	YAQLAYLVFG	TQVDDFSTFQ	ECIFTQFRII	LGDINFAEIE	EANRVLGPIY	FTTFVFFMFF	ILLNMFLAII	NDTYSEVKSD	LAQQKAEMEL
701	711	721	731	741	751	761	771	781	791
SDLIRKGYHK	ALVKLKLKKN	TVDDISESLR	QGGGKLNFDE	LRQDLKGKGH	TDAEIEAIFT	KYDQDGDQEL	TEHEHQQMRD	DLEKEREDLD	LDHSSLPRPM
801	811	821	831	841	851	861	871	881	891
SSRSFPRSLD	DSEEDDDEDS	GHSSRRRGSI	SSGVSYEEFQ	VLVRRVDRME	HSIGSIVSKI	DAVIVKLEIM	ERAKLKRREV	LGRLLDGVAE	DERLGRDSEI
901	911	921	931	941	951	961
HREQMERLVR	EELERWESDD	AASQISHGLG	TPVGLNGQPR	PRSSRPSSSQ	STEGMEGAGG	NGSSNVHV

Reference

ID	Publication
14	Liu Y, Chen J, Sethi A, Li QK, Chen L, Collins B, Gillet LC, Wollscheid B, Zhang H, Aebersold R: Glycoproteomic analysis of prostate cancer tissues by SWATH mass spectrometry discovers N-acylethanolamine acid amidase and protein tyrosine kinase 7 as signatures for tumor aggressiveness. Molecular & Cellular Proteomics 2014, 13:1753-1768.
16	Deeb SJ, Cox J, Schmidt-Supprian M, Mann M: N-linked Glycosylation Enrichment for In-depth Cell Surface Proteomics of Diffuse Large B-cell Lymphoma Subtypes. Molecular & Cellular Proteomics 2014, 13:240-251.
33	Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.
34	Sun S, Zhang B, Aiyetan P, Zhou J-Y, Shah P, Yang W, Levine DA, Zhang Z, Chan DW, Zhang H: Analysis of N-glycoproteins using Genomic N-glycosite Prediction. Journal of Proteome Research 2013, 12:5609-5615.
40	Li X, Jiang J, Zhao X, Wang J, Han H, Zhao Y, Peng B, Zhong R, Ying W, Qian X: N-glycoproteome Analysis of the Secretome of Human Metastatic Hepatocellular Carcinoma Cell Lines Combining Hydrazide Chemistry, HILIC Enrichment and Mass Spectrometry. Plos One 2013, 8.
48	Danzer C, Eckhardt K, Schmidt A, Fankhauser N, Ribrioux S, Wollscheid B, Mueller L, Schiess R, Zuellig R, Lehmann R, et al: Comprehensive Description of the N-Glycoproteome of Mouse Pancreatic beta-Cells and Human Islets. Journal of Proteome Research 2012, 11:1598-1608.
66	Jia W, Lu Z, Fu Y, Wang H-P, Wang L-H, Chi H, Yuan Z-F, Zheng Z-B, Song L-N, Han H-H, et al: A Strategy for Precise and Large Scale Identification of Core Fucosylated Glycoproteins. Molecular & Cellular Proteomics 2009, 8:913-923.