Detail

UniProtKB-Q13683


Protein	Integrin alpha-7
Gene	ITGA7
Status	Reviewed
Source	Breast cancer xenografts; Colorectal tumor; Liver; Non-small Cell Lung Carcinoma; Ovarian tumor; Pancreatic islets
Years	2009-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
86	ALPGQQAnRTGGLF	2014(33);
786	ALDPAEKPLCLSNEnASHVE	2014(33);
786	ALDPAEKPLCLSNEnASHVECELGNPMK	2014(33);
989	nITLDCAR	2014(22); 2015(unpublished);2015(unpublished);
989	KnITLDCAR	2014(22);
989	KKnITLDCAR	2013(34); 2014(33);
1025	LWnSTFLEE	2012(48); 2014(33);
1025	IWnSTFIEEYSAVK	2014(32);
1025	LWnSTFLEEYSAVK	2009(64); 2012(48); 2014(18); 2014(22); 2014(33); 2015(unpublished);
1045	AnITVK	2015(unpublished);

Sequence

1	11	21	31	41	51	61	71	81	91
MAGARSRDPW	GASGICYLFG	SLLVELLFSR	AVAFNLDVMG	ALRKEGEPGS	LFGFSVALHR	QLQPRPQSWL	LVGAPQALAL	PGQQANRTGG	LFACPLSLEE
101	111	121	131	141	151	161	171	181	191
TDCYRVDIDQ	GADMQKESKE	NQWLGVSVRS	QGPGGKIVTC	AHRYEARQRV	DQILETRDMI	GRCFVLSQDL	AIRDELDGGE	WKFCEGRPQG	HEQFGFCQQG
201	211	221	231	241	251	261	271	281	291
TAAAFSPDSH	YLLFGAPGTY	NWKGTARVEL	CAQGSADLAH	LDDGPYEAGG	EKEQDPRLIP	VPANSYFGLL	FVTNIDSSDP	DQLVYKTLDP	ADRLPGPAGD
301	311	321	331	341	351	361	371	381	391
LALNSYLGFS	IDSGKGLVRA	EELSFVAGAP	RANHKGAVVI	LRKDSASRLV	PEVMLSGERL	TSGFGYSLAV	ADLNSDGWPD	LIVGAPYFFE	RQEELGGAVY
401	411	421	431	441	451	461	471	481	491
VYLNQGGHWA	GISPLRLCGS	PDSMFGISLA	VLGDLNQDGF	PDIAVGAPFD	GDGKVFIYHG	SSLGVVAKPS	QVLEGEAVGI	KSFGYSLSGS	LDMDGNQYPD
501	511	521	531	541	551	561	571	581	591
LLVGSLADTA	VLFRARPILH	VSHEVSIAPR	SIDLEQPNCA	GGHSVCVDLR	VCFSYIAVPS	SYSPTVALDY	VLDADTDRRL	RGQVPRVTFL	SRNLEEPKHQ
601	611	621	631	641	651	661	671	681	691
ASGTVWLKHQ	HDRVCGDAMF	QLQENVKDKL	RAIVVTLSYS	LQTPRLRRQA	PGQGLPPVAP	ILNAHQPSTQ	RAEIHFLKQG	CGEDKICQSN	LQLVRARFCT
701	711	721	731	741	751	761	771	781	791
RVSDTEFQPL	PMDVDGTTAL	FALSGQPVIG	LELMVTNLPS	DPAQPQADGD	DAHEAQLLVM	LPDSLHYSGV	RALDPAEKPL	CLSNENASHV	ECELGNPMKR
801	811	821	831	841	851	861	871	881	891
GAQVTFYLIL	STSGISIETT	ELEVELLLAT	ISEQELHPVS	ARARVFIELP	LSIAGMAIPQ	QLFFSGVVRG	ERAMQSERDV	GSKVKYEVTV	SNQGQSLRTL
901	911	921	931	941	951	961	971	981	991
GSAFLNIMWP	HEIANGKWLL	YPMQVELEGG	QGPGQKGLCS	PRPNILHLDV	DSRDRRRREL	EPPEQQEPGE	RQEPSMSWWP	VSSAEKKKNI	TLDCARGTAN
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
CVVFSCPLYS	FDRAAVLHVW	GRLWNSTFLE	EYSAVKSLEV	IVRANITVKS	SIKNLMLRDA	STVIPVMVYL	DPMAVVAEGV	PWWVILLAVL	AGLLVLALLV
1101	1111	1121	1131	1141	1151	1161	1171	1181
LLLWKMGFFK	RAKHPEATVP	QYHAVKIPRE	DRQQFKEEKT	GTILRNNWGS	PRREGPDAHP	ILAADGHPEL	GPDGHPGPGT	A

Reference

ID	Publication
18	Hirao Y, Matsuzaki H, Iwaki J, Kuno A, Kaji H, Ohkura T, Togayachi A, Abe M, Nomura M, Noguchi M, et al: Glycoproteomics Approach for Identifying Glycobiomarker Candidate Molecules for Tissue Type Classification of Non-small Cell Lung Carcinoma. Journal of Proteome Research 2014, 13:4705-4716.
22	Nicastri A, Gaspari M, Sacco R, Elia L, Gabriele C, Romano R, Rizzuto A, Cuda G: N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue. Journal of Proteome Research 2014, 13:4932-4941.
32	Zhang Z, Sun Z, Zhu J, Liu J, Huang G, Ye M, Zou H: High-Throughput Determination of the Site-Specific N-Sialoglycan Occupancy Rates by Differential Oxidation of Glycoproteins Followed with Quantitative Glycoproteomics Analysis. Analytical Chemistry 2014, 86:9830-9837.
33	Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.
34	Sun S, Zhang B, Aiyetan P, Zhou J-Y, Shah P, Yang W, Levine DA, Zhang Z, Chan DW, Zhang H: Analysis of N-glycoproteins using Genomic N-glycosite Prediction. Journal of Proteome Research 2013, 12:5609-5615.
48	Danzer C, Eckhardt K, Schmidt A, Fankhauser N, Ribrioux S, Wollscheid B, Mueller L, Schiess R, Zuellig R, Lehmann R, et al: Comprehensive Description of the N-Glycoproteome of Mouse Pancreatic beta-Cells and Human Islets. Journal of Proteome Research 2012, 11:1598-1608.
64	Chen R, Jiang X, Sun D, Han G, Wang F, Ye M, Wang L, Zou H: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. J Proteome Res 2009, 8:651-661.