| Protein | Integrin alpha-9 |
| Gene | ITGA9 |
| Status | Reviewed |
| Source | Breast cancer xenografts; Colorectal tumor; HEK293 cell line (embryonic kidney); Liver; Liver tumor (HCC); OVCAR-3 cell line (Ovarian cancer); Ovarian tumor; Prostate; Prostate tumor |
| Years | 2009-2015 |
| Site | Identified Peptides | Year(Publication ID) |
|---|---|---|
| 225 | nLTDNTYLK | 2015(1); |
| 225 | VInITDNTYIK | 2014(32); 2014(32); |
| 225 | VLnLTDNTYLK | 2009(64); 2014(14); 2014(15); 2014(22); 2014(33); 2015(unpublished);2015(1); 2015(unpublished);2015(unpublished); |
| 225 | WAGTIKVLnLTDNTY | 2014(33); |
| 612 | nQTVFER | 2014(22); 2014(33); 2015(unpublished); |
| 612 | IAQKnQTVFER | 2014(33); |
| 612 | KKGQKIAQKnQTVF | 2014(33); |
| 672 | DAnVSFNVSR | 2014(33); |
| 672 | DAnVSFNVSRELF | 2014(33); |
| 676 | nVSRELF | 2014(33); |
| 676 | DANVSFnVSR | 2014(33); |
| 676 | DANVSFnVSRELF | 2014(33); |
| 854 | GnCSFQK | 2014(32); 2014(33); |
| 904 | TAHCnF | 2014(33); |
| 904 | nFSALAK | 2015(1); |
| 904 | TAHCnFSAL | 2014(33); |
| 904 | TAHCnFSALAK | 2014(33); |
| 904 | VLDCEKPGISCLTAHCnF | 2014(33); |
| 904 | VLDCEKPGISCLTAHCnFSALAK | 2014(33); |
| 904 | KVLDCEKPGISCLTAHCnFSALAK | 2014(33); |
| 1 | 11 | 21 | 31 | 41 | 51 | 61 | 71 | 81 | 91 |
| MGGPAAPRGA | GRLRALLLAL | VVAGIPAGAY | NLDPQRPVHF | QGPADSFFGY | AVLEHFHDNT | RWVLVGAPKA | DSKYSPSVKS | PGAVFKCRVH | TNPDRRCTEL |
| 101 | 111 | 121 | 131 | 141 | 151 | 161 | 171 | 181 | 191 |
| DMARGKNRGT | SCGKTCREDR | DDEWMGVSLA | RQPKADGRVL | ACAHRWKNIY | YEADHILPHG | FCYIIPSNLQ | AKGRTLIPCY | EEYKKKYGEE | HGSCQAGIAG |
| 201 | 211 | 221 | 231 | 241 | 251 | 261 | 271 | 281 | 291 |
| FFTEELVVMG | APGSFYWAGT | IKVLNLTDNT | YLKLNDEVIM | NRRYTYLGYA | VTAGHFSHPS | TIDVVGGAPQ | DKGIGKVYIF | RADRRSGTLI | KIFQASGKKM |
| 301 | 311 | 321 | 331 | 341 | 351 | 361 | 371 | 381 | 391 |
| GSYFGSSLCA | VDLNGDGLSD | LLVGAPMFSE | IRDEGQVTVY | INRGNGALEE | QLALTGDGAY | NAHFGESIAS | LDDLDNDGFP | DVAIGAPKED | DFAGAVYIYH |
| 401 | 411 | 421 | 431 | 441 | 451 | 461 | 471 | 481 | 491 |
| GDAGGIVPQY | SMKLSGQKIN | PVLRMFGQSI | SGGIDMDGNG | YPDVTVGAFM | SDSVVLLRAR | PVITVDVSIF | LPGSINITAP | QCHDGQQPVN | CLNVTTCFSF |
| 501 | 511 | 521 | 531 | 541 | 551 | 561 | 571 | 581 | 591 |
| HGKHVPGEIG | LNYVLMADVA | KKEKGQMPRV | YFVLLGETMG | QVTEKLQLTY | MEETCRHYVA | HVKRRVQDVI | SPIVFEAAYS | LSEHVTGEEE | RELPPLTPVL |
| 601 | 611 | 621 | 631 | 641 | 651 | 661 | 671 | 681 | 691 |
| RWKKGQKIAQ | KNQTVFERNC | RSEDCAADLQ | LQGKLLLSSM | DEKTLYLALG | AVKNISLNIS | ISNLGDDAYD | ANVSFNVSRE | LFFINMWQKE | EMGISCELLE |
| 701 | 711 | 721 | 731 | 741 | 751 | 761 | 771 | 781 | 791 |
| SDFLKCSVGF | PFMRSKSKYE | FSVIFDTSHL | SGEEEVLSFI | VTAQSGNTER | SESLHDNTLV | LMVPLMHEVD | TSITGIMSPT | SFVYGESVDA | ANFIQLDDLE |
| 801 | 811 | 821 | 831 | 841 | 851 | 861 | 871 | 881 | 891 |
| CHFQPINITL | QVYNTGPSTL | PGSSVSISFP | NRLSSGGAEM | FHVQEMVVGQ | EKGNCSFQKN | PTPCIIPQEQ | ENIFHTIFAF | FTKSGRKVLD | CEKPGISCLT |
| 901 | 911 | 921 | 931 | 941 | 951 | 961 | 971 | 981 | 991 |
| AHCNFSALAK | EESRTIDIYM | LLNTEILKKD | SSSVIQFMSR | AKVKVDPALR | VVEIAHGNPE | EVTVVFEALH | NLEPRGYVVG | WIIAISLLVG | ILIFLLLAVL |
| 1001 | 1011 | 1021 | 1031 | ||||||
| LWKMGFFRRR | YKEIIEAEKN | RKENEDSWDW | VQKNQ |
| ID | Publication |
|---|---|
| 1 | Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication. |
| 14 | Liu Y, Chen J, Sethi A, Li QK, Chen L, Collins B, Gillet LC, Wollscheid B, Zhang H, Aebersold R: Glycoproteomic analysis of prostate cancer tissues by SWATH mass spectrometry discovers N-acylethanolamine acid amidase and protein tyrosine kinase 7 as signatures for tumor aggressiveness. Molecular & Cellular Proteomics 2014, 13:1753-1768. |
| 15 | Chen R, Seebun D, Ye M, Zou H, Figeys D: Site-specific characterization of cell membrane N-glycosylation with integrated hydrophilic interaction chromatography solid phase extraction and LC-MS/MS. Journal of Proteomics 2014, 103:194-203. |
| 22 | Nicastri A, Gaspari M, Sacco R, Elia L, Gabriele C, Romano R, Rizzuto A, Cuda G: N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue. Journal of Proteome Research 2014, 13:4932-4941. |
| 32 | Zhang Z, Sun Z, Zhu J, Liu J, Huang G, Ye M, Zou H: High-Throughput Determination of the Site-Specific N-Sialoglycan Occupancy Rates by Differential Oxidation of Glycoproteins Followed with Quantitative Glycoproteomics Analysis. Analytical Chemistry 2014, 86:9830-9837. |
| 33 | Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721. |
| 64 | Chen R, Jiang X, Sun D, Han G, Wang F, Ye M, Wang L, Zou H: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. J Proteome Res 2009, 8:651-661. |