| Protein | Nidogen-2 |
| Gene | NID2 |
| Status | Reviewed |
| Source | Breast tumor; Colorectal tumor; DLBCL cell lines (Diffuse large B-cell lymphoma); IGROV-1/CP cell line (Ovarian cancer)IGROV-1/CP; Liver; Liver tumor (HCC); OVCAR-3 cell line (Ovarian cancer); Ovarian cancer cell lines; Ovarian tumor; Pancreatic islets; Platelet; Prostate; Prostate tumor; SKOV-3 cell line (Ovarian cancer); Serum; Urine; ovarian tumor |
| Years | 2007-2015 |
| Site | Identified Peptides | Year(Publication ID) |
|---|---|---|
| 658 | nFTAHISPYK | 2015(1); |
| 658 | VSAnFTAHISPY | 2014(33); |
| 658 | VSAnFTAHISPYK | 2015(unpublished); |
| 658 | TNIQGQVPYVSAnFTAH | 2015(unpublished); |
| 658 | TNIQGQVPYVSAnFTAHISPYK | 2015(unpublished);2015(unpublished); |
| 693 | GAInQTW | 2014(33); |
| 693 | GAInQTWSY | 2014(33); |
| 693 | GAInQTWSYR | 2014(33); 2015(unpublished); |
| 693 | SLTFGAInQTW | 2014(33); |
| 693 | DYSLTFGAInQTW | 2014(33); |
| 693 | SLTFGAInQTWSY | 2014(33); |
| 693 | DYSITFGAInQTWSYR | 2014(32); |
| 693 | DYSLTFGAInQTWSYR | 2013(34); 2014(33); 2015(1); 2015(unpublished);2015(unpublished);2007;2007; |
| 703 | nITYQVCR | 2015(1); |
| 703 | RIHQnITY | 2014(33); |
| 703 | IHQnITYQVCR | 2007(75); 2007(3); 2012(48); 2012(34); 2013(34); 2013(14); 2014(16); 2014(22); 2014(32); 2014(32); 2014(33); 2014(1); 2015(unpublished);2015(unpublished);2015(unpublished);2015(unpublished);2007(unpublished);2007;2007;2007;2007; |
| 1124 | IGYLPLnGTR | 2007(64); 2009(unpublished);2007(unpublished);2007; |
| 1124 | GQQIGYLPLnGTR | 2015(unpublished); |
| 1124 | TQGQQIGYLPLnGTR | 2007(75); 2011(54); 2012(3); 2014(33); 2015(unpublished); |
| 1124 | LYTQGQQIGYLPLnGTR | 2014(33); |
| 1124 | LLYTQGQQIGYLPLnGTR | 2014(33); 2015(unpublished); |
| 1124 | SQPGTTPACIPTVAPPMVRPTPRPDVTPPSVGTFLLYTQGQQIGYLPLnGTR | 2013(42); |
| 1 | 11 | 21 | 31 | 41 | 51 | 61 | 71 | 81 | 91 |
| MEGDRVAGRP | VLSSLPVLLL | LPLLMLRAAA | LHPDELFPHG | ESWGDQLLQE | GDDESSAVVK | LANPLHFYEA | RFSNLYVGTN | GIISTQDFPR | ETQYVDYDFP |
| 101 | 111 | 121 | 131 | 141 | 151 | 161 | 171 | 181 | 191 |
| TDFPAIAPFL | ADIDTSHGRG | RVLYREDTSP | AVLGLAARYV | RAGFPRSARF | TPTHAFLATW | EQVGAYEEVK | RGALPSGELN | TFQAVLASDG | SDSYALFLYP |
| 201 | 211 | 221 | 231 | 241 | 251 | 261 | 271 | 281 | 291 |
| ANGLQFLGTR | PKESYNVQLQ | LPARVGFCRG | EADDLKSEGP | YFSLTSTEQS | VKNLYQLSNL | GIPGVWAFHI | GSTSPLDNVR | PAAVGDLSAA | HSSVPLGRSF |
| 301 | 311 | 321 | 331 | 341 | 351 | 361 | 371 | 381 | 391 |
| SHATALESDY | NEDNLDYYDV | NEEEAEYLPG | EPEEALNGHS | SIDVSFQSKV | DTKPLEESST | LDPHTKEGTS | LGEVGGPDLK | GQVEPWDERE | TRSPAPPEVD |
| 401 | 411 | 421 | 431 | 441 | 451 | 461 | 471 | 481 | 491 |
| RDSLAPSWET | PPPYPENGSI | QPYPDGGPVP | SEMDVPPAHP | EEEIVLRSYP | ASGHTTPLSR | GTYEVGLEDN | IGSNTEVFTY | NAANKETCEH | NHRQCSRHAF |
| 501 | 511 | 521 | 531 | 541 | 551 | 561 | 571 | 581 | 591 |
| CTDYATGFCC | HCQSKFYGNG | KHCLPEGAPH | RVNGKVSGHL | HVGHTPVHFT | DVDLHAYIVG | NDGRAYTAIS | HIPQPAAQAL | LPLTPIGGLF | GWLFALEKPG |
| 601 | 611 | 621 | 631 | 641 | 651 | 661 | 671 | 681 | 691 |
| SENGFSLAGA | AFTHDMEVTF | YPGEETVRIT | QTAEGLDPEN | YLSIKTNIQG | QVPYVSANFT | AHISPYKELY | HYSDSTVTST | SSRDYSLTFG | AINQTWSYRI |
| 701 | 711 | 721 | 731 | 741 | 751 | 761 | 771 | 781 | 791 |
| HQNITYQVCR | HAPRHPSFPT | TQQLNVDRVF | ALYNDEERVL | RFAVTNQIGP | VKEDSDPTPG | NPCYDGSHMC | DTTARCHPGT | GVDYTCECAS | GYQGDGRNCV |
| 801 | 811 | 821 | 831 | 841 | 851 | 861 | 871 | 881 | 891 |
| DENECATGFH | RCGPNSVCIN | LPGSYRCECR | SGYEFADDRH | TCILITPPAN | PCEDGSHTCA | PAGQARCVHH | GGSTFSCACL | PGYAGDGHQC | TDVDECSENR |
| 901 | 911 | 921 | 931 | 941 | 951 | 961 | 971 | 981 | 991 |
| CHPAATCYNT | PGSFSCRCQP | GYYGDGFQCI | PDSTSSLTPC | EQQQRHAQAQ | YAYPGARFHI | PQCDEQGNFL | PLQCHGSTGF | CWCVDPDGHE | VPGTQTPPGS |
| 1001 | 1011 | 1021 | 1031 | 1041 | 1051 | 1061 | 1071 | 1081 | 1091 |
| TPPHCGPSPE | PTQRPPTICE | RWRENLLEHY | GGTPRDDQYV | PQCDDLGHFI | PLQCHGKSDF | CWCVDKDGRE | VQGTRSQPGT | TPACIPTVAP | PMVRPTPRPD |
| 1101 | 1111 | 1121 | 1131 | 1141 | 1151 | 1161 | 1171 | 1181 | 1191 |
| VTPPSVGTFL | LYTQGQQIGY | LPLNGTRLQK | DAAKTLLSLH | GSIIVGIDYD | CRERMVYWTD | VAGRTISRAG | LELGAEPETI | VNSGLISPEG | LAIDHIRRTM |
| 1201 | 1211 | 1221 | 1231 | 1241 | 1251 | 1261 | 1271 | 1281 | 1291 |
| YWTDSVLDKI | ESALLDGSER | KVLFYTDLVN | PRAIAVDPIR | GNLYWTDWNR | EAPKIETSSL | DGENRRILIN | TDIGLPNGLT | FDPFSKLLCW | ADAGTKKLEC |
| 1301 | 1311 | 1321 | 1331 | 1341 | 1351 | 1361 | 1371 | ||
| TLPDGTGRRV | IQNNLKYPFS | IVSYADHFYH | TDWRRDGVVS | VNKHSGQFTD | EYLPEQRSHL | YGITAVYPYC | PTGRK |
| ID | Publication |
|---|---|
| 1 | Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication. |
| 3 | Tian Y, Almaraz RT, Choi CH, Li QK, Saeui C, Li D, Shah P, Bhattacharya R, Yarema KJ, Zhang H: Identification of sialylated glycoproteins from metabolically oligosaccharide engineered pancreatic cells. Clinical proteomics 2015, 12:11. |
| 14 | Liu Y, Chen J, Sethi A, Li QK, Chen L, Collins B, Gillet LC, Wollscheid B, Zhang H, Aebersold R: Glycoproteomic analysis of prostate cancer tissues by SWATH mass spectrometry discovers N-acylethanolamine acid amidase and protein tyrosine kinase 7 as signatures for tumor aggressiveness. Molecular & Cellular Proteomics 2014, 13:1753-1768. |
| 16 | Deeb SJ, Cox J, Schmidt-Supprian M, Mann M: N-linked Glycosylation Enrichment for In-depth Cell Surface Proteomics of Diffuse Large B-cell Lymphoma Subtypes. Molecular & Cellular Proteomics 2014, 13:240-251. |
| 22 | Nicastri A, Gaspari M, Sacco R, Elia L, Gabriele C, Romano R, Rizzuto A, Cuda G: N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue. Journal of Proteome Research 2014, 13:4932-4941. |
| 32 | Zhang Z, Sun Z, Zhu J, Liu J, Huang G, Ye M, Zou H: High-Throughput Determination of the Site-Specific N-Sialoglycan Occupancy Rates by Differential Oxidation of Glycoproteins Followed with Quantitative Glycoproteomics Analysis. Analytical Chemistry 2014, 86:9830-9837. |
| 33 | Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721. |
| 34 | Sun S, Zhang B, Aiyetan P, Zhou J-Y, Shah P, Yang W, Levine DA, Zhang Z, Chan DW, Zhang H: Analysis of N-glycoproteins using Genomic N-glycosite Prediction. Journal of Proteome Research 2013, 12:5609-5615. |
| 42 | Ma C, Zhao X, Han H, Tong W, Zhang Q, Qin P, Chang C, Peng B, Ying W, Qian X: N-linked glycoproteome profiling of human serum using tandem enrichment and multiple fraction concatenation. Electrophoresis 2013, 34:2440-2450. |
| 48 | Danzer C, Eckhardt K, Schmidt A, Fankhauser N, Ribrioux S, Wollscheid B, Mueller L, Schiess R, Zuellig R, Lehmann R, et al: Comprehensive Description of the N-Glycoproteome of Mouse Pancreatic beta-Cells and Human Islets. Journal of Proteome Research 2012, 11:1598-1608. |
| 54 | Tian Y, Yao Z, Roden R, Zhang H: Identification of glycoproteins associated with different histological subtypes of ovarian tumors using quantitative glycoproteomics. Proteomics 2011, 11:4677-4687. |
| 64 | Chen R, Jiang X, Sun D, Han G, Wang F, Ye M, Wang L, Zou H: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. J Proteome Res 2009, 8:651-661. |
| 75 | Sun B, Ranish JA, Utleg AG, White JT, Yan X, Lin B, Hood L: Shotgun glycopeptide capture approach coupled with mass Spectrometry for comprehensive glycoproteomics. Molecular & Cellular Proteomics 2007, 6:141-149. |