Detail


Protein	Inositol 1,4,5-trisphosphate receptor type 2
Gene	ITPR2
Status	Reviewed
Source	Breast cancer xenografts; DLBCL cell lines (Diffuse large B-cell lymphoma); Liver
Years	2014-2015

Site	Identified Peptides	Year(Publication ID)
2456	EnCSPTIPASNTADEEYEDGIER	2014(16); 2014(33); 2015(unpublished);

Sequence

1	11	21	31	41	51	61	71	81	91
MTEKMSSFLY	IGDIVSLYAE	GSVNGFISTL	GLVDDRCVVH	PEAGDLANPP	KKFRDCLFKV	CPMNRYSAQK	QYWKAKQAKQ	GNHTEAALLK	KLQHAAELEQ
101	111	121	131	141	151	161	171	181	191
KQNESENKKL	LGEIVKYSNV	IQLLHIKSNK	YLTVNKRLPA	LLEKNAMRVS	LDAAGNEGSW	FYIHPFWKLR	SEGDNIVVGD	KVVLMPVNAG	QPLHASNIEL
201	211	221	231	241	251	261	271	281	291
LDNPGCKEVN	AVNCNTSWKI	TLFMKYSSYR	EDVLKGGDVV	RLFHAEQEKF	LTCDEYEKKQ	HIFLRTTLRQ	SATSATSSKA	LWEIEVVHHD	PCRGGAGQWN
301	311	321	331	341	351	361	371	381	391
SLFRFKHLAT	GNYLAAELNP	DYRDAQNEGK	NVRDGVPPTS	KKKRQAGEKI	MYTLVSVPHG	NDIASLFELD	ATTLQRADCL	VPRNSYVRLR	HLCTNTWVTS
401	411	421	431	441	451	461	471	481	491
TSIPIDTDEE	RPVMLKIGTC	QTKEDKEAFA	IVSVPLSEVR	DLDFANDANK	VLATTVKKLE	NGTITQNERR	FVTKLLEDLI	FFVADVPNNG	QEVLDVVITK
501	511	521	531	541	551	561	571	581	591
PNRERQKLMR	EQNILAQVFG	ILKAPFKEKA	GEGSMLRLED	LGDQRYAPYK	YMLRLCYRVL	RHSQQDYRKN	QEYIAKNFCV	MQSQIGYDIL	AEDTITALLH
601	611	621	631	641	651	661	671	681	691
NNRKLLEKHI	TAKEIETFVS	LLRRNREPRF	LDYLSDLCVS	NTTAIPVTQE	LICKFMLSPG	NADILIQTKV	VSMQADNPME	SSILSDDIDD	EEVWLYWIDS
701	711	721	731	741	751	761	771	781	791
NKEPHGKAIR	HLAQEAKEGT	KADLEVLTYY	RYQLNLFARM	CLDRQYLAIN	QISTQLSVDL	ILRCVSDESL	PFDLRASFCR	LMLHMHVDRD	PQESVVPVRY
801	811	821	831	841	851	861	871	881	891
ARLWTEIPTK	ITIHEYDSIT	DSSRNDMKRK	FALTMEFVEE	YLKEVVNQPF	PFGDKEKNKL	TFEVVHLARN	LIYFGFYSFS	ELLRLTRTLL	AILDIVQAPM
901	911	921	931	941	951	961	971	981	991
SSYFERLSKF	QDGGNNVMRT	IHGVGEMMTQ	MVLSRGSIFP	MSVPDVPPSI	HPSKQGSPTE	HEDVTVMDTK	LKIIEILQFI	LSVRLDYRIS	YMLSIYKKEF
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
GEDNDNAETS	ASGSPDTLLP	SAIVPDIDEI	AAQAETMFAG	RKEKNPVQLD	DEGGRTFLRV	LIHLIMHDYP	PLLSGALQLL	FKHFSQRAEV	LQAFKQVQLL
1101	1111	1121	1131	1141	1151	1161	1171	1181	1191
VSNQDVDNYK	QIKADLDQLR	LTVEKSELWV	EKSSNYENGE	IGESQVKGGE	EPIEESNILS	PVQDGTKKPQ	IDSNKSNNYR	IVKEILIRLS	KLCVQNKKCR
1201	1211	1221	1231	1241	1251	1261	1271	1281	1291
NQHQRLLKNM	GAHSVVLDLL	QIPYEKNDEK	MNEVMNLAHT	FLQNFCRGNP	QNQVLLHKHL	NLFLTPGLLE	AETMRHIFMN	NYHLCNEISE	RVVQHFVHCI
1301	1311	1321	1331	1341	1351	1361	1371	1381	1391
ETHGRHVEYL	RFLQTIVKAD	GKYVKKCQDM	VMTELINGGE	DVLIFYNDRA	SFPILLHMMC	SERDRGDESG	PLAYHITLVE	LLAACTEGKN	VYTEIKCNSL
1401	1411	1421	1431	1441	1451	1461	1471	1481	1491
LPLDDIVRVV	THDDCIPEVK	IAYVNFVNHC	YVDTEVEMKE	IYTSNHIWKL	FENFLVDMAR	VCNTTTDRKH	ADIFLEKCVT	ESIMNIVSGF	FNSPFSDNST
1501	1511	1521	1531	1541	1551	1561	1571	1581	1591
SLQTHQPVFI	QLLQSAFRIY	NCTWPNPAQK	ASVESCIRTL	AEVAKNRGIA	IPVDLDSQVN	TLFMKSHSNM	VQRAAMGWRL	SARSGPRFKE	ALGGPAWDYR
1601	1611	1621	1631	1641	1651	1661	1671	1681	1691
NIIEKLQDVV	ASLEHQFSPM	MQAEFSVLVD	VLYSPELLFP	EGSDARIRCG	AFMSKLINHT	KKLMEKEEKL	CIKILQTLRE	MLEKKDSFVE	EGNTLRKILL
1701	1711	1721	1731	1741	1751	1761	1771	1781	1791
NRYFKGDYSI	GVNGHLSGAY	SKTAQVGGSF	SGQDSDKMGI	SMSDIQCLLD	KEGASELVID	VIVNTKNDRI	FSEGIFLGIA	LLEGGNTQTQ	YSFYQQLHEQ
1801	1811	1821	1831	1841	1851	1861	1871	1881	1891
KKSEKFFKVL	YDRMKAAQKE	IRSTVTVNTI	DLGNKKRDDD	NELMTSGPRM	RVRDSTLHLK	EGMKGQLTEA	SSATSKAYCV	YRREMDPEID	IMCTGPEAGN
1901	1911	1921	1931	1941	1951	1961	1971	1981	1991
TEEKSAEEVT	MSPAIAIMQP	ILRFLQLLCE	NHNRELQNFL	RNQNNKTNYN	LVCETLQFLD	CICGSTTGGL	GLLGLYINEK	NVALVNQNLE	SLTEYCQGPC
2001	2011	2021	2031	2041	2051	2061	2071	2081	2091
HENQTCIATH	ESNGIDIIIA	LILNDINPLG	KYRMDLVLQL	KNNASKLLLA	IMESRHDSEN	AERILFNMRP	RELVDVMKNA	YNQGLECDHG	DDEGGDDGVS
2101	2111	2121	2131	2141	2151	2161	2171	2181	2191
PKDVGHNIYI	LAHQLARHNK	LLQQMLKPGS	DPDEGDEALK	YYANHTAQIE	IVRHDRTMEQ	IVFPVPNICE	YLTRESKCRV	FNTTERDEQG	SKVNDFFQQT
2201	2211	2221	2231	2241	2251	2261	2271	2281	2291
EDLYNEMKWQ	KKIRNNPALF	WFSRHISLWG	SISFNLAVFI	NLAVALFYPF	GDDGDEGTLS	PLFSVLLWIA	VAICTSMLFF	FSKPVGIRPF	LVSIMLRSIY
2301	2311	2321	2331	2341	2351	2361	2371	2381	2391
TIGLGPTLIL	LGAANLCNKI	VFLVSFVGNR	GTFTRGYRAV	ILDMAFLYHV	AYVLVCMLGL	FVHEFFYSFL	LFDLVYREET	LLNVIKSVTR	NGRSIILTAV
2401	2411	2421	2431	2441	2451	2461	2471	2481	2491
LALILVYLFS	IIGFLFLKDD	FTMEVDRLKN	RTPVTGSHQV	PTMTLTTMME	ACAKENCSPT	IPASNTADEE	YEDGIERTCD	TLLMCIVTVL	NQGLRNGGGV
2501	2511	2521	2531	2541	2551	2561	2571	2581	2591
GDVLRRPSKD	EPLFAARVVY	DLLFYFIVII	IVLNLIFGVI	IDTFADLRSE	KQKKEEILKT	TCFICGLERD	KFDNKTVSFE	EHIKSEHNMW	HYLYFIVLVK
2601	2611	2621	2631	2641	2651	2661	2671	2681	2691
VKDPTEYTGP	ESYVAQMIVE	KNLDWFPRMR	AMSLVSNEGD	SEQNEIRSLQ	EKLESTMSLV	KQLSGQLAEL	KEQMTEQRKN	KQRLGFLGSN	TPHVNHHMPP
2701
H

UniProtKB-Q14571

Glycosites

Sequence

Reference

ID	Publication
16	Deeb SJ, Cox J, Schmidt-Supprian M, Mann M: N-linked Glycosylation Enrichment for In-depth Cell Surface Proteomics of Diffuse Large B-cell Lymphoma Subtypes. Molecular & Cellular Proteomics 2014, 13:240-251.
33	Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.