Detail

UniProtKB-Q14767


Protein	Latent-transforming growth factor beta-binding protein 2
Gene	LTBP2
Status	Reviewed
Source	Breast Cancer cell lines; Breast cancer xenografts; Colorectal tumor; Liver; Non-small Cell Lung Carcinoma; OVCAR-3 cell line (Ovarian cancer); Ovarian tumor; Prostate tumor; Urine; umbilical vein Endothelial Cells
Years	2007-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
181	PGWTTAnSTNHCI	2013(37);
343	SSPWGInITEKIK	2013(37);
343	EHPSSPWGLnLTEK	2015(unpublished);
343	DGTQQAVPLEHPSSPWGLnLTEK	2014(33); 2015(unpublished);2015(1); 2015(unpublished);2015(unpublished);
421	CPAnSTGKF	2014(33);
421	DECWCPAnSTGK	2013(44); 2014(22); 2014(32); 2014(33); 2015(unpublished);2015(unpublished);2015;2015;2007;2007;
421	ECWCPAnSTGKFC	2013(37);
616	LnLTHCQDINE	2014(33);
616	RLnLTHCQDINE	2014(33);
616	RLnLTHCQDINECLTLGLCK	2015(unpublished);
1568	CMnSTSSTEDLPDHDIHMDICWK	2007(18); 2014(unpublished);2007(unpublished);2007;

Sequence

1	11	21	31	41	51	61	71	81	91
MRPRTKARSP	GRALRNPWRG	FLPLTLALFV	GAGHAQRDPV	GRYEPAGGDA	NRLRRPGGSY	PAAAAAKVYS	LFREQDAPVA	GLQPVERAQP	GWGSPRRPTE
101	111	121	131	141	151	161	171	181	191
AEARRPSRAQ	QSRRVQPPAQ	TRRSTPLGQQ	QPAPRTRAAP	ALPRLGTPQR	SGAAPPTPPR	GRLTGRNVCG	GQCCPGWTTA	NSTNHCIKPV	CEPPCQNRGS
201	211	221	231	241	251	261	271	281	291
CSRPQLCVCR	SGFRGARCEE	VIPDEEFDPQ	NSRLAPRRWA	ERSPNLRRSS	AAGEGTLARA	QPPAPQSPPA	PQSPPAGTLS	GLSQTHPSQQ	HVGLSRTVRL
301	311	321	331	341	351	361	371	381	391
HPTATASSQL	SSNALPPGPG	LEQRDGTQQA	VPLEHPSSPW	GLNLTEKIKK	IKIVFTPTIC	KQTCARGHCA	NSCERGDTTT	LYSQGGHGHD	PKSGFRIYFC
401	411	421	431	441	451	461	471	481	491
QIPCLNGGRC	IGRDECWCPA	NSTGKFCHLP	IPQPDREPPG	RGSRPRALLE	APLKQSTFTL	PLSNQLASVN	PSLVKVHIHH	PPEASVQIHQ	VAQVRGGVEE
501	511	521	531	541	551	561	571	581	591
ALVENSVETR	PPPWLPASPG	HSLWDSNNIP	ARSGEPPRPL	PPAAPRPRGL	LGRCYLNTVN	GQCANPLLEL	TTQEDCCGSV	GAFWGVTLCA	PCPPRPASPV
601	611	621	631	641	651	661	671	681	691
IENGQLECPQ	GYKRLNLTHC	QDINECLTLG	LCKDAECVNT	RGSYLCTCRP	GLMLDPSRSR	CVSDKAISML	QGLCYRSLGP	GTCTLPLAQR	ITKQICCCSR
701	711	721	731	741	751	761	771	781	791
VGKAWGSECE	KCPLPGTEAF	REICPAGHGY	TYASSDIRLS	MRKAEEEELA	RPPREQGQRS	SGALPGPAER	QPLRVVTDTW	LEAGTIPDKG	DSQAGQVTTS
801	811	821	831	841	851	861	871	881	891
VTHAPAWVTG	NATTPPMPEQ	GIAEIQEEQV	TPSTDVLVTL	STPGIDRCAA	GATNVCGPGT	CVNLPDGYRC	VCSPGYQLHP	SQAYCTDDNE	CLRDPCKGKG
901	911	921	931	941	951	961	971	981	991
RCINRVGSYS	CFCYPGYTLA	TSGATQECQD	INECEQPGVC	SGGQCTNTEG	SYHCECDQGY	IMVRKGHCQD	INECRHPGTC	PDGRCVNSPG	SYTCLACEEG
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
YRGQSGSCVD	VNECLTPGVC	AHGKCTNLEG	SFRCSCEQGY	EVTSDEKGCQ	DVDECASRAS	CPTGLCLNTE	GSFACSACEN	GYWVNEDGTA	CEDLDECAFP
1101	1111	1121	1131	1141	1151	1161	1171	1181	1191
GVCPSGVCTN	TAGSFSCKDC	DGGYRPSPLG	DSCEDVDECE	DPQSSCLGGE	CKNTVGSYQC	LCPQGFQLAN	GTVCEDVNEC	MGEEHCAPHG	ECLNSHGSFF
1201	1211	1221	1231	1241	1251	1261	1271	1281	1291
CLCAPGFVSA	EGGTSCQDVD	ECATTDPCVG	GHCVNTEGSF	NCLCETGFQP	SPESGECVDI	DECEDYGDPV	CGTWKCENSP	GSYRCVLGCQ	PGFHMAPNGD
1301	1311	1321	1331	1341	1351	1361	1371	1381	1391
CIDIDECAND	TMCGSHGFCD	NTDGSFRCLC	DQGFEISPSG	WDCVDVNECE	LMLAVCGAAL	CENVEGSFLC	LCASDLEEYD	AQEGHCRPRG	AGGQSMSEAP
1401	1411	1421	1431	1441	1451	1461	1471	1481	1491
TGDHAPAPTR	MDCYSGQKGH	APCSSVLGRN	TTQAECCCTQ	GASWGDACDL	CPSEDSAEFS	EICPSGKGYI	PVEGAWTFGQ	TMYTDADECV	IFGPGLCPNG
1501	1511	1521	1531	1541	1551	1561	1571	1581	1591
RCLNTVPGYV	CLCNPGFHYD	ASHKKCEDHD	ECQDLACENG	ECVNTEGSFH	CFCSPPLTLD	LSQQRCMNST	SSTEDLPDHD	IHMDICWKKV	TNDVCSEPLR
1601	1611	1621	1631	1641	1651	1661	1671	1681	1691
GHRTTYTECC	CQDGEAWSQQ	CALCPPRSSE	VYAQLCNVAR	IEAEREAGVH	FRPGYEYGPG	PDDLHYSIYG	PDGAPFYNYL	GPEDTVPEPA	FPNTAGHSAD
1701	1711	1721	1731	1741	1751	1761	1771	1781	1791
RTPILESPLQ	PSELQPHYVA	SHPEPPAGFE	GLQAEECGIL	NGCENGRCVR	VREGYTCDCF	EGFQLDAAHM	ACVDVNECDD	LNGPAVLCVH	GYCENTEGSY
1801	1811	1821
RCHCSPGYVA	EAGPPHCTAK	E

Reference

ID	Publication
1	Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
18	Hirao Y, Matsuzaki H, Iwaki J, Kuno A, Kaji H, Ohkura T, Togayachi A, Abe M, Nomura M, Noguchi M, et al: Glycoproteomics Approach for Identifying Glycobiomarker Candidate Molecules for Tissue Type Classification of Non-small Cell Lung Carcinoma. Journal of Proteome Research 2014, 13:4705-4716.
22	Nicastri A, Gaspari M, Sacco R, Elia L, Gabriele C, Romano R, Rizzuto A, Cuda G: N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue. Journal of Proteome Research 2014, 13:4932-4941.
32	Zhang Z, Sun Z, Zhu J, Liu J, Huang G, Ye M, Zou H: High-Throughput Determination of the Site-Specific N-Sialoglycan Occupancy Rates by Differential Oxidation of Glycoproteins Followed with Quantitative Glycoproteomics Analysis. Analytical Chemistry 2014, 86:9830-9837.
33	Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.
37	Boersema PJ, Geiger T, Wisniewski JR, Mann M: Quantification of the N-glycosylated Secretome by Super-SILAC During Breast Cancer Progression and in Human Blood Samples. Molecular & Cellular Proteomics 2013, 12:158-171.
44	Yin X, Bern M, Xing Q, Ho J, Viner R, Mayr M: Glycoproteomic Analysis of the Secretome of Human Endothelial Cells. Molecular & Cellular Proteomics 2013, 12:956-978.