Detail

UniProtKB-Q15596


Protein	Nuclear receptor coactivator 2
Gene	NCOA2
Status	Reviewed
Source	Breast cancer xenografts; Colorectal tumor; Hela cell line (cervical cancer); LNCap/PC3 cell lines (Prostate cancer); Liver; Prostate tumor; Serum; Urine
Years	2007-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
7	MSGMGEnTS	2007(unpublished);
1217	nITIR	2014(33);
1217	nITLR	2014(33);
1217	nLTIR	2014(33);
1217	nLTLR	2014(33);
1217	VnITLR	2007(33); 2014(unpublished);2007(unpublished);2007;
1217	VnLTIR	2007(unpublished);
1217	VnLTLR	2007(22); 2014(2); 2015(12); 2015(unpublished);2015(unpublished);2015;2015;2007;2007;
1271	GQGLnMTPSMVAPSGMPATMSNPR	2007(unpublished);2015(unpublished);2007;2007;

Sequence

1	11	21	31	41	51	61	71	81	91
MSGMGENTSD	PSRAETRKRK	ECPDQLGPSP	KRNTEKRNRE	QENKYIEELA	ELIFANFNDI	DNFNFKPDKC	AILKETVKQI	RQIKEQEKAA	AANIDEVQKS
101	111	121	131	141	151	161	171	181	191
DVSSTGQGVI	DKDALGPMML	EALDGFFFVV	NLEGNVVFVS	ENVTQYLRYN	QEELMNKSVY	SILHVGDHTE	FVKNLLPKSI	VNGGSWSGEP	PRRNSHTFNC
201	211	221	231	241	251	261	271	281	291
RMLVKPLPDS	EEEGHDNQEA	HQKYETMQCF	AVSQPKSIKE	EGEDLQSCLI	CVARRVPMKE	RPVLPSSESF	TTRQDLQGKI	TSLDTSTMRA	AMKPGWEDLV
301	311	321	331	341	351	361	371	381	391
RRCIQKFHAQ	HEGESVSYAK	RHHHEVLRQG	LAFSQIYRFS	LSDGTLVAAQ	TKSKLIRSQT	TNEPQLVISL	HMLHREQNVC	VMNPDLTGQT	MGKPLNPISS
401	411	421	431	441	451	461	471	481	491
NSPAHQALCS	GNPGQDMTLS	SNINFPINGP	KEQMGMPMGR	FGGSGGMNHV	SGMQATTPQG	SNYALKMNSP	SQSSPGMNPG	QPTSMLSPRH	RMSPGVAGSP
501	511	521	531	541	551	561	571	581	591
RIPPSQFSPA	GSLHSPVGVC	SSTGNSHSYT	NSSLNALQAL	SEGHGVSLGS	SLASPDLKMG	NLQNSPVNMN	PPPLSKMGSL	DSKDCFGLYG	EPSEGTTGQA
601	611	621	631	641	651	661	671	681	691
ESSCHPGEQK	ETNDPNLPPA	VSSERADGQS	RLHDSKGQTK	LLQLLTTKSD	QMEPSPLASS	LSDTNKDSTG	SLPGSGSTHG	TSLKEKHKIL	HRLLQDSSSP
701	711	721	731	741	751	761	771	781	791
VDLAKLTAEA	TGKDLSQESS	STAPGSEVTI	KQEPVSPKKK	ENALLRYLLD	KDDTKDIGLP	EITPKLERLD	SKTDPASNTK	LIAMKTEKEE	MSFEPGDQPG
801	811	821	831	841	851	861	871	881	891
SELDNLEEIL	DDLQNSQLPQ	LFPDTRPGAP	AGSVDKQAII	NDLMQLTAEN	SPVTPVGAQK	TALRISQSTF	NNPRPGQLGR	LLPNQNLPLD	ITLQSPTGAG
901	911	921	931	941	951	961	971	981	991
PFPPIRNSSP	YSVIPQPGMM	GNQGMIGNQG	NLGNSSTGMI	GNSASRPTMP	SGEWAPQSSA	VRVTCAATTS	AMNRPVQGGM	IRNPAASIPM	RPSSQPGQRQ
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
TLQSQVMNIG	PSELEMNMGG	PQYSQQQAPP	NQTAPWPESI	LPIDQASFAS	QNRQPFGSSP	DDLLCPHPAA	ESPSDEGALL	DQLYLALRNF	DGLEEIDRAL
1101	1111	1121	1131	1141	1151	1161	1171	1181	1191
GIPELVSQSQ	AVDPEQFSSQ	DSNIMLEQKA	PVFPQQYASQ	AQMAQGSYSP	MQDPNFHTMG	QRPSYATLRM	QPRPGLRPTG	LVQNQPNQLR	LQLQHRLQAQ
1201	1211	1221	1231	1241	1251	1261	1271	1281	1291
QNRQPLMNQI	SNVSNVNLTL	RPGVPTQAPI	NAQMLAQRQR	EILNQHLRQR	QMHQQQQVQQ	RTLMMRGQGL	NMTPSMVAPS	GMPATMSNPR	IPQANAQQFP
1301	1311	1321	1331	1341	1351	1361	1371	1381	1391
FPPNYGISQQ	PDPGFTGATT	PQSPLMSPRM	AHTQSPMMQQ	SQANPAYQAP	SDINGWAQGN	MGGNSMFSQQ	SPPHFGQQAN	TSMYSNNMNI	NVSMATNTGG
1401	1411	1421	1431	1441	1451	1461
MSSMNQMTGQ	ISMTSVTSVP	TSGLSSMGPE	QVNDPALRGG	NLFPNQLPGM	DMIKQEGDTT	RKYC

Reference

ID	Publication
2	Shah P, Wang X, Yang W, Eshghi ST, Sun S, Hoti N, Chen L, Yang S, Pasay J, Rubin A: Integrated Proteomic and Glycoproteomic Analyses of Prostate Cancer Cells Reveal Glycoprotein Alteration in Protein Abundance and Glycosylation. Molecular & Cellular Proteomics 2015, 14:2753-2763.
12	Weng Y, Sui Z, Jiang H, Shan Y, Chen L, Zhang S, Zhang L, Zhang Y: Releasing N-glycan from Peptide N-terminus by N-terminal Succinylation Assisted Enzymatic Deglycosylation. Scientific Reports 2015, 5.
22	Nicastri A, Gaspari M, Sacco R, Elia L, Gabriele C, Romano R, Rizzuto A, Cuda G: N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue. Journal of Proteome Research 2014, 13:4932-4941.
33	Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.