Detail

Contains

UniProtKB-Q16549


Protein	Proprotein convertase subtilisin/kexin type 7
Gene	PCSK7
Status	Reviewed
Source	Breast cancer xenografts; DLBCL cell lines (Diffuse large B-cell lymphoma); Liver
Years	2014-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
167	DInVTGVWER	2014(16); 2014(33);
511	SIEVIWnVSR	2014(16);
511	SLEVLWnVSR	2015(unpublished);

Sequence

1	11	21	31	41	51	61	71	81	91
MPKGRQKVPH	LDAPLGLPTC	LWLELAGLFL	LVPWVMGLAG	TGGPDGQGTG	GPSWAVHLES	LEGDGEEETL	EQQADALAQA	AGLVNAGRIG	ELQGHYLFVQ
101	111	121	131	141	151	161	171	181	191
PAGHRPALEV	EAIRQQVEAV	LAGHEAVRWH	SEQRLLRRAK	RSVHFNDPKY	PQQWHLNNRR	SPGRDINVTG	VWERNVTGRG	VTVVVVDDGV	EHTIQDIAPN
201	211	221	231	241	251	261	271	281	291
YSPEGSYDLN	SNDPDPMPHP	DVENGNHHGT	RCAGEIAAVP	NNSFCAVGVA	YGSRIAGIRV	LDGPLTDSME	AVAFNKHYQI	NDIYSCSWGP	DDDGKTVDGP
301	311	321	331	341	351	361	371	381	391
HQLGKAALQH	GVIAGRQGFG	SIFVVASGNG	GQHNDNCNYD	GYANSIYTVT	IGAVDEEGRM	PFYAEECASM	LAVTFSGGDK	MLRSIVTTDW	DLQKGTGCTE
401	411	421	431	441	451	461	471	481	491
GHTGTSAAAP	LAAGMIALML	QVRPCLTWRD	VQHIIVFTAT	RYEDRRAEWV	TNEAGFSHSH	QHGFGLLNAW	RLVNAAKIWT	SVPYLASYVS	PVLKENKAIP
501	511	521	531	541	551	561	571	581	591
QSPRSLEVLW	NVSRMDLEMS	GLKTLEHVAV	TVSITHPRRG	SLELKLFCPS	GMMSLIGAPR	SMDSDPNGFN	DWTFSTVRCW	GERARGTYRL	VIRDVGDESF
601	611	621	631	641	651	661	671	681	691
QVGILRQWQL	TLYGSVWSAV	DIRDRQRLLE	SAMSGKYLHD	DFALPCPPGL	KIPEEDGYTI	TPNTLKTLVL	VGCFTVFWTV	YYMLEVYLSQ	RNVASNQVCR
701	711	721	731	741	751	761	771	781
SGPCHWPHRS	RKAKEEGTEL	ESVPLCSSKD	PDEVETESRG	PPTTSDLLAP	DLLEQGDWSL	SQNKSALDCP	HQHLDVPHGK	EEQIC

Reference

ID	Publication
16	Deeb SJ, Cox J, Schmidt-Supprian M, Mann M: N-linked Glycosylation Enrichment for In-depth Cell Surface Proteomics of Diffuse Large B-cell Lymphoma Subtypes. Molecular & Cellular Proteomics 2014, 13:240-251.
33	Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.