Detail

Contains

UniProtKB-Q16819


Protein	Meprin A subunit alpha
Gene	MEP1A
Status	Reviewed
Source	Colorectal tumor; HepG2 cell line (Liver); HuH-7 cell line (Liver)
Years	2013-2014

Glycosites

Site	Identified Peptides	Year(Publication ID)
222	nASVPTITAK	2014(22);
258	MYnCTTTHTLLDHCTFEK	2013(38); 2014(22);
440	nFSQVLENTSK	2013(38); 2014(22);
447	NFSQVLEnTSK	2013(38); 2014(22);
539	SHTSPAInDTVIWDRPSR	2013(38); 2013(38); 2014(22);

Sequence

1	11	21	31	41	51	61	71	81	91
MAWIRSTCIL	FFTLLFAHIA	AVPIKYLPEE	NVHDADFGEQ	KDISEINLAA	GLDLFQGDIL	LQKSRNGLRD	PNTRWTFPIP	YILADNLGLN	AKGAILYAFE
101	111	121	131	141	151	161	171	181	191
MFRLKSCVDF	KPYEGESSYI	IFQQFDGCWS	EVGDQHVGQN	ISIGQGCAYK	AIIEHEILHA	LGFYHEQSRT	DRDDYVNIWW	DQILSGYQHN	FDTYDDSLIT
201	211	221	231	241	251	261	271	281	291
DLNTPYDYES	LMHYQPFSFN	KNASVPTITA	KIPEFNSIIG	QRLDFSAIDL	ERLNRMYNCT	TTHTLLDHCT	FEKANICGMI	QGTRDDTDWA	HQDSAQAGEV
301	311	321	331	341	351	361	371	381	391
DHTLLGQCTG	AGYFMQFSTS	SGSAEEAALL	ESRILYPKRK	QQCLQFFYKM	TGSPSDRLVV	WVRRDDSTGN	VRKLVKVQTF	QGDDDHNWKI	AHVVLKEEQK
401	411	421	431	441	451	461	471	481	491
FRYLFQGTKG	DPQNSTGGIY	LDDITLTETP	CPTGVWTVRN	FSQVLENTSK	GDKLQSPRFY	NSEGYGFGVT	LYPNSRESSG	YLRLAFHVCS	GENDAILEWP
501	511	521	531	541	551	561	571	581	591
VENRQVIITI	LDQEPDVRNR	MSSSMVFTTS	KSHTSPAIND	TVIWDRPSRV	GTYHTDCNCF	RSIDLGWSGF	ISHQMLKRRS	FLKNDDLIIF	VDFEDITHLS
601	611	621	631	641	651	661	671	681	691
QTEVPTKGKR	LSPQGLILQG	QEQQVSEEGS	GKAMLEEALP	VSLSQGQPSR	QKRSVENTGP	LEDHNWPQYF	RDPCDPNPCQ	NDGICVNVKG	MASCRCISGH
701	711	721	731	741
AFFYTGERCQ	AVQVHGSVLG	MVIGGTAGVI	FLTFSIIAIL	SQRPRK

Reference

ID	Publication
22	Nicastri A, Gaspari M, Sacco R, Elia L, Gabriele C, Romano R, Rizzuto A, Cuda G: N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue. Journal of Proteome Research 2014, 13:4932-4941.
38	Kaji H, Ocho M, Togayachi A, Kuno A, Sogabe M, Ohkura T, Nozaki H, Angata T, Chiba Y, Ozaki H, et al: Glycoproteomic Discovery of Serological Biomarker Candidates for HCV/HBV Infection-Associated Liver Fibrosis and Hepatocellular Carcinoma. Journal of Proteome Research 2013, 12:2630-2640.