| Protein | Membrane primary amine oxidase |
| Gene | AOC3 |
| Status | Reviewed |
| Source | Bladder tumor; Breast Cancer cell lines; Breast cancer xenografts; Breast tumor; Colorectal tumor; Liver; Liver tumor (HCC); OVCAR-3 cell line (Ovarian cancer); Ovarian tumor; Pancreatic islets; Plasma; Platelet; Prostate; Prostate tumor; Serum; Urine; ovarian tumor; plasma |
| Years | 2005-2015 |
| Site | Identified Peptides | Year(Publication ID) |
|---|---|---|
| 137 | QPQPnVSE | 2014(33); |
| 137 | FGRQPQPnVSE | 2009(64); |
| 137 | GRQPQPnVSEL | 2014(33); |
| 137 | FGRQPQPnVSEL | 2014(33); |
| 137 | AIVFFGRQPQPnVSEL | 2014(33); |
| 137 | QPQPnVSELVVGPLPHP | 2014(33); |
| 137 | EALAIVFFGRQPQPnVSE | 2014(33); |
| 137 | PnVSELVVGPLPHPSYMR | 2012(48); |
| 137 | QPQPnVSELVVGPLPHPSY | 2014(33); |
| 137 | GRQPQPnVSELVVGPLPHPSY | 2014(33); |
| 137 | QPQPnVSELVVGPLPHPSYMR | 2013(42); 2014(14); 2014(22); 2014(33); 2015(unpublished);2015(unpublished);2007;2007; |
| 137 | FGRQPQPnVSELVVGPLPHPSY | 2014(33); |
| 137 | GRQPQPnVSELVVGPLPHPSYM | 2014(33); |
| 137 | GRQPQPnVSELVVGPLPHPSYMRDVTVERHGGPLPY | 2014(33); |
| 137 | FGRQPQPnVSELVVGPLPHPSYMRDVTVERHGGPLPY | 2014(33); |
| 232 | nISGAGFF | 2014(33); |
| 232 | YnISGAGFF | 2014(33); |
| 232 | YYnISGAGFF | 2014(33); |
| 232 | GLYYnISGAGF | 2014(33); |
| 232 | FGLYYnISGAGF | 2014(33); |
| 232 | GLYYnISGAGFF | 2014(33); |
| 232 | nISGAGFFLHHVGLE | 2014(33); |
| 232 | GLYYnISGAGFFLHHVGLE | 2014(33); |
| 294 | nGTGGSWSLK | 2015(1); |
| 294 | LIPDnGTGGSWS | 2009(64); |
| 294 | VVLIPDnGTGGSW | 2014(33); |
| 294 | VVLIPDnGTGGSWS | 2009(64); |
| 294 | VNVVLIPDnGTGGSW | 2014(33); |
| 294 | AGLVNVVLIPDnGTGGSW | 2014(33); |
| 294 | EAGLVNVVLIPDnGTGGSW | 2014(33); |
| 294 | AGLVNVVLIPDnGTGGSWSLK | 2014(33); |
| 294 | YYDSLAQLEAQFEAGLVNVVLIPDnGTGGSWSLK | 2007(unpublished);2007(unpublished);2007(unpublished); |
| 592 | ASnHSNKW | 2014(33); |
| 592 | LASnHSNK | 2012(48); |
| 592 | YLYLASnH | 2014(33); |
| 592 | LASnHSNKW | 2014(33); |
| 592 | YLASnHSNK | 2012(48); 2014(14); 2014(33); |
| 592 | LYLASnHSNK | 2014(14); 2014(33); 2015(unpublished); |
| 592 | YLASnHSNKW | 2014(33); |
| 592 | YIYIASnHSNK | 2014(32); 2014(32); |
| 592 | YLYLASnHSNK | 2005( 81); 2009(64); 2009(66); 2012(3); 2012(48); 2013(34); 2013(45); 2014(13); 2014(14); 2014(22); 2014(33); 2015(8); 2015(10); 2015(unpublished);2015(unpublished);2015(unpublished);2015;2015;2015;2007;2007;2007; |
| 592 | YLYLASnHSNKW | 2014(33); |
| 592 | YIYIASnHSNKWG | 2013(37); |
| 592 | YLYLASnHSNKWGHPR | 2014(33); |
| 592 | LLEMEEQAAFLVGSATPRYLYLASnHSNK | 2015(unpublished); |
| 618 | PQnSSMAR | 2012(48); 2014(14); |
| 618 | PLPQnSSMAR | 2012(48); |
| 618 | FAGEPLPQnSS | 2009(64); |
| 618 | AGEPLPQnSSMA | 2014(33); |
| 618 | FAGEPLPQnSSM | 2009(64); |
| 618 | GEPLPQnSSMAR | 2014(33); |
| 618 | AGEPLPQnSSMAR | 2012(48); 2014(14); 2014(33); 2015(unpublished); |
| 618 | SFAGEPLPQnSSM | 2014(33); |
| 618 | FAGEPLPQnSSMAR | 2012(48); 2014(14); 2014(33); 2015(unpublished); |
| 618 | SFAGEPLPQnSSMA | 2014(33); |
| 618 | AGEPLPQnSSMARGF | 2014(33); |
| 618 | SFAGEPLPQnSSMAR | 2014(14); 2014(33); 2015(unpublished); |
| 618 | MLSFAGEPLPQnSSMAR | 2014(14); 2015(unpublished); |
| 618 | SFAGEPLPQnSSMARGF | 2014(33); |
| 618 | IQMISFAGEPIPQnSSMAR | 2014(32); 2014(32); |
| 618 | IQMLSFAGEPLPQnSSMAR | 2005( 81); 2009(64); 2011(54); 2011(55); 2012(48); 2013(34); 2014(13); 2014(14); 2014(22); 2014(33); 2015(unpublished);2015(unpublished);2015(unpublished);2007(unpublished);2007(Unpublished ); 2007;2007;2007 ; |
| 666 | nETIAGK | 2015(unpublished); |
| 666 | INnETIAGK | 2014(33); |
| 666 | VDFSDFINnE | 2014(33); |
| 666 | DFINnETIAGK | 2014(14); 2015(unpublished); |
| 666 | INnETIAGKDL | 2014(33); |
| 666 | FSDFINnETIAGK | 2014(33); |
| 666 | INnETIAGKDLVAW | 2014(33); |
| 666 | SDFINnETIAGKDL | 2014(33); |
| 666 | VDFSDFINnETIAGK | 2014(14); 2014(33); 2015(unpublished); |
| 666 | APTVDFSDFINnETIAGK | 2014(14); 2015(unpublished); |
| 666 | APTVDFSDFINnETIAGKDL | 2014(33); |
| 666 | NQNDPWAPTVDFSDFINnETIAGK | 2014(33); |
| 666 | EEEPSSSSVFNQNDPWAPTVDFSDFINnETIAGK | 2015(unpublished);2007(unpublished);2007(unpublished);2007(unpublished);2007; |
| 666 | KEEEPSSSSVFNQNDPWAPTVDFSDFINnETIAGK | 2005(81); 2009(64); 2013(34); 2014(32); 2014(33); 2015(unpublished);2015(unpublished); |
| 1 | 11 | 21 | 31 | 41 | 51 | 61 | 71 | 81 | 91 |
| MNQKTILVLL | ILAVITIFAL | VCVLLVGRGG | DGGEPSQLPH | CPSVSPSAQP | WTHPGQSQLF | ADLSREELTA | VMRFLTQRLG | PGLVDAAQAR | PSDNCVFSVE |
| 101 | 111 | 121 | 131 | 141 | 151 | 161 | 171 | 181 | 191 |
| LQLPPKAAAL | AHLDRGSPPP | AREALAIVFF | GRQPQPNVSE | LVVGPLPHPS | YMRDVTVERH | GGPLPYHRRP | VLFQEYLDID | QMIFNRELPQ | ASGLLHHCCF |
| 201 | 211 | 221 | 231 | 241 | 251 | 261 | 271 | 281 | 291 |
| YKHRGRNLVT | MTTAPRGLQS | GDRATWFGLY | YNISGAGFFL | HHVGLELLVN | HKALDPARWT | IQKVFYQGRY | YDSLAQLEAQ | FEAGLVNVVL | IPDNGTGGSW |
| 301 | 311 | 321 | 331 | 341 | 351 | 361 | 371 | 381 | 391 |
| SLKSPVPPGP | APPLQFYPQG | PRFSVQGSRV | ASSLWTFSFG | LGAFSGPRIF | DVRFQGERLV | YEISLQEALA | IYGGNSPAAM | TTRYVDGGFG | MGKYTTPLTR |
| 401 | 411 | 421 | 431 | 441 | 451 | 461 | 471 | 481 | 491 |
| GVDCPYLATY | VDWHFLLESQ | APKTIRDAFC | VFEQNQGLPL | RRHHSDLYSH | YFGGLAETVL | VVRSMSTLLN | YDYVWDTVFH | PSGAIEIRFY | ATGYISSAFL |
| 501 | 511 | 521 | 531 | 541 | 551 | 561 | 571 | 581 | 591 |
| FGATGKYGNQ | VSEHTLGTVH | THSAHFKVDL | DVAGLENWVW | AEDMVFVPMA | VPWSPEHQLQ | RLQVTRKLLE | MEEQAAFLVG | SATPRYLYLA | SNHSNKWGHP |
| 601 | 611 | 621 | 631 | 641 | 651 | 661 | 671 | 681 | 691 |
| RGYRIQMLSF | AGEPLPQNSS | MARGFSWERY | QLAVTQRKEE | EPSSSSVFNQ | NDPWAPTVDF | SDFINNETIA | GKDLVAWVTA | GFLHIPHAED | IPNTVTVGNG |
| 701 | 711 | 721 | 731 | 741 | 751 | 761 | |||
| VGFFLRPYNF | FDEDPSFYSA | DSIYFRGDQD | AGACEVNPLA | CLPQAAACAP | DLPAFSHGGF | SHN |
| ID | Publication |
|---|---|
| 1 | Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication. |
| 3 | Tian Y, Almaraz RT, Choi CH, Li QK, Saeui C, Li D, Shah P, Bhattacharya R, Yarema KJ, Zhang H: Identification of sialylated glycoproteins from metabolically oligosaccharide engineered pancreatic cells. Clinical proteomics 2015, 12:11. |
| 8 | Ma C, Zhang Q, Qu JY, Zhao XY, Li X, Liu YP, Wang PG: A precise approach in large scale core-fucosylated glycoprotein identification with low- and high-normalized collision energy. Journal of Proteomics 2015, 114:61-70. |
| 10 | Tan ZJ, Yin HD, Nie S, Lin ZX, Zhu JH, Ruffin MT, Anderson MA, Simone DM, Lubman DM: Large-Scale Identification of Core-Fucosylated Glycopeptide Sites in Pancreatic Cancer Serum Using Mass Spectrometry. Journal of Proteome Research 2015, 14:1968-1978. |
| 13 | Yang W, Laeyendecker O, Wendel SK, Zhang B, Sun S, Zhou J-Y, Ao M, Moore RD, Jackson JB, Zhang H: Glycoproteomic Study Reveals Altered Plasma Proteins Associated with HIV Elite Suppressors. Theranostics 2014, 4:1153. |
| 14 | Liu Y, Chen J, Sethi A, Li QK, Chen L, Collins B, Gillet LC, Wollscheid B, Zhang H, Aebersold R: Glycoproteomic analysis of prostate cancer tissues by SWATH mass spectrometry discovers N-acylethanolamine acid amidase and protein tyrosine kinase 7 as signatures for tumor aggressiveness. Molecular & Cellular Proteomics 2014, 13:1753-1768. |
| 22 | Nicastri A, Gaspari M, Sacco R, Elia L, Gabriele C, Romano R, Rizzuto A, Cuda G: N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue. Journal of Proteome Research 2014, 13:4932-4941. |
| 32 | Zhang Z, Sun Z, Zhu J, Liu J, Huang G, Ye M, Zou H: High-Throughput Determination of the Site-Specific N-Sialoglycan Occupancy Rates by Differential Oxidation of Glycoproteins Followed with Quantitative Glycoproteomics Analysis. Analytical Chemistry 2014, 86:9830-9837. |
| 33 | Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721. |
| 34 | Sun S, Zhang B, Aiyetan P, Zhou J-Y, Shah P, Yang W, Levine DA, Zhang Z, Chan DW, Zhang H: Analysis of N-glycoproteins using Genomic N-glycosite Prediction. Journal of Proteome Research 2013, 12:5609-5615. |
| 37 | Boersema PJ, Geiger T, Wisniewski JR, Mann M: Quantification of the N-glycosylated Secretome by Super-SILAC During Breast Cancer Progression and in Human Blood Samples. Molecular & Cellular Proteomics 2013, 12:158-171. |
| 42 | Ma C, Zhao X, Han H, Tong W, Zhang Q, Qin P, Chang C, Peng B, Ying W, Qian X: N-linked glycoproteome profiling of human serum using tandem enrichment and multiple fraction concatenation. Electrophoresis 2013, 34:2440-2450. |
| 45 | Zhou H, Froehlich JW, Briscoe AC, Lee RS: The GlycoFilter: A Simple and Comprehensive Sample Preparation Platform for Proteomics, N-Glycomics and Glycosylation Site Assignment. Molecular & Cellular Proteomics 2013, 12:2981-2991. |
| 48 | Danzer C, Eckhardt K, Schmidt A, Fankhauser N, Ribrioux S, Wollscheid B, Mueller L, Schiess R, Zuellig R, Lehmann R, et al: Comprehensive Description of the N-Glycoproteome of Mouse Pancreatic beta-Cells and Human Islets. Journal of Proteome Research 2012, 11:1598-1608. |
| 54 | Tian Y, Yao Z, Roden R, Zhang H: Identification of glycoproteins associated with different histological subtypes of ovarian tumors using quantitative glycoproteomics. Proteomics 2011, 11:4677-4687. |
| 55 | Tian Y, Bova GS, Zhang H: Quantitative glycoproteomic analysis of optimal cutting temperature-embedded frozen tissues identifying glycoproteins associated with aggressive prostate cancer. Analytical chemistry 2011, 83:7013-7019. |
| 64 | Chen R, Jiang X, Sun D, Han G, Wang F, Ye M, Wang L, Zou H: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. J Proteome Res 2009, 8:651-661. |
| 66 | Jia W, Lu Z, Fu Y, Wang H-P, Wang L-H, Chi H, Yuan Z-F, Zheng Z-B, Song L-N, Han H-H, et al: A Strategy for Precise and Large Scale Identification of Core Fucosylated Glycoproteins. Molecular & Cellular Proteomics 2009, 8:913-923. |
| 81 | Liu T, Qian WJ, Gritsenko MA, Camp DG, Monroe ME, Moore RJ, Smith RD: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. Journal of Proteome Research 2005, 4:2070-2080. |