| Protein | Collectin-12 |
| Gene | COLEC12 |
| Status | Reviewed |
| Source | Breast Cancer cell lines; Breast cancer xenografts; Colorectal cancer cell line, HCT-116 (colorectal cancer); Colorectal tumor; HEK293 cell line (embryonic kidney); HEK293T cell line (embryonic kidney), HEK293T cell line (embryonic kidney); LNCap/PC3 cell lines (Prostate cancer); OVCAR-3 cell line (Ovarian cancer); Ovarian tumor; Prostate; Prostate tumor; Spermatozoa; Urine; ovarian tumor |
| Years | 2007-2015 |
| Site | Identified Peptides | Year(Publication ID) |
|---|---|---|
| 67 | MDnVTGGMETSR | 2014(22); 2015(unpublished);2015(unpublished);2007;2007; |
| 159 | ETLEnNSFLITTVNK | 2011(58); 2014(14); 2014(22); 2015(unpublished);2015(unpublished);2015(unpublished);2015(unpublished);2015(unpublished);2015(unpublished); |
| 168 | ETLENNSFLITTVnK | 2011(58); 2014(14); 2014(22); 2015(unpublished);2015(unpublished);2015(unpublished);2015(unpublished);2015(unpublished);2015(unpublished); |
| 210 | nLTQVQQR | 2015(1); |
| 271 | VQSLQTLAAnNSALAK | 2011(54); 2014(14); 2014(15); 2014(22); 2015(unpublished);2015(unpublished);2015;2015;2015;2015;2007;2007; |
| 280 | ANnDTLEDMNSQLN | 2014(14); 2015(unpublished); |
| 280 | ANnDTLEDMNSQLNSFTGQMENITTISQANEQNLK | 2015(unpublished);2015(unpublished); |
| 299 | nITTISQANEQNLK | 2015(1); |
| 299 | ANNDTLEDMNSQLNSFTGQMEnITTISQANEQNLK | 2015(unpublished);2015(unpublished); |
| 323 | DLQDLHKDAEnR | 2015(unpublished);2015(unpublished); |
| 349 | nISYTAHHLR | 2015(1); |
| 349 | FQLFETDIVNIISnISYTAHHLR | 2015(2); 2015(9); |
| 386 | nNTLANIR | 2015(1); |
| 386 | DDITSInNTIANI | 2013(37); |
| 386 | HTDDITSInNTIANIR | 2013(43); |
| 386 | HTDDLTSLnNTLANIR | 2014(14); 2014(15); 2014(22); 2015(unpublished);2015(2); 2015(unpublished);2015(unpublished); |
| 416 | LDTEVAnLSVIMEEMK | 2011(54); 2015(unpublished);2015(unpublished);2015;2007;2007; |
| 416 | SRLDTEVAnLSVIMEEMK | 2015(unpublished);2015(unpublished); |
| 437 | nFTILQGPPGPR | 2015(unpublished); |
| 1 | 11 | 21 | 31 | 41 | 51 | 61 | 71 | 81 | 91 |
| MKDDFAEEEE | VQSFGYKRFG | IQEGTQCTKC | KNNWALKFSI | ILLYILCALL | TITVAILGYK | VVEKMDNVTG | GMETSRQTYD | DKLTAVESDL | KKLGDQTGKK |
| 101 | 111 | 121 | 131 | 141 | 151 | 161 | 171 | 181 | 191 |
| AISTNSELST | FRSDILDLRQ | QLREITEKTS | KNKDTLEKLQ | ASGDALVDRQ | SQLKETLENN | SFLITTVNKT | LQAYNGYVTN | LQQDTSVLQG | NLQNQMYSHN |
| 201 | 211 | 221 | 231 | 241 | 251 | 261 | 271 | 281 | 291 |
| VVIMNLNNLN | LTQVQQRNLI | TNLQRSVDDT | SQAIQRIKND | FQNLQQVFLQ | AKKDTDWLKE | KVQSLQTLAA | NNSALAKANN | DTLEDMNSQL | NSFTGQMENI |
| 301 | 311 | 321 | 331 | 341 | 351 | 361 | 371 | 381 | 391 |
| TTISQANEQN | LKDLQDLHKD | AENRTAIKFN | QLEERFQLFE | TDIVNIISNI | SYTAHHLRTL | TSNLNEVRTT | CTDTLTKHTD | DLTSLNNTLA | NIRLDSVSLR |
| 401 | 411 | 421 | 431 | 441 | 451 | 461 | 471 | 481 | 491 |
| MQQDLMRSRL | DTEVANLSVI | MEEMKLVDSK | HGQLIKNFTI | LQGPPGPRGP | RGDRGSQGPP | GPTGNKGQKG | EKGEPGPPGP | AGERGPIGPA | GPPGERGGKG |
| 501 | 511 | 521 | 531 | 541 | 551 | 561 | 571 | 581 | 591 |
| SKGSQGPKGS | RGSPGKPGPQ | GSSGDPGPPG | PPGKEGLPGP | QGPPGFQGLQ | GTVGEPGVPG | PRGLPGLPGV | PGMPGPKGPP | GPPGPSGAVV | PLALQNEPTP |
| 601 | 611 | 621 | 631 | 641 | 651 | 661 | 671 | 681 | 691 |
| APEDNGCPPH | WKNFTDKCYY | FSVEKEIFED | AKLFCEDKSS | HLVFINTREE | QQWIKKQMVG | RESHWIGLTD | SERENEWKWL | DGTSPDYKNW | KAGQPDNWGH |
| 701 | 711 | 721 | 731 | 741 | |||||
| GHGPGEDCAG | LIYAGQWNDF | QCEDVNNFIC | EKDRETVLSS | AL |
| ID | Publication |
|---|---|
| 1 | Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication. |
| 2 | Shah P, Wang X, Yang W, Eshghi ST, Sun S, Hoti N, Chen L, Yang S, Pasay J, Rubin A: Integrated Proteomic and Glycoproteomic Analyses of Prostate Cancer Cells Reveal Glycoprotein Alteration in Protein Abundance and Glycosylation. Molecular & Cellular Proteomics 2015, 14:2753-2763. |
| 9 | Smeekens JM, Chen WX, Wu RH: Mass Spectrometric Analysis of the Cell Surface N-Glycoproteome by Combining Metabolic Labeling and Click Chemistry. Journal of the American Society for Mass Spectrometry 2015, 26:604-614. |
| 14 | Liu Y, Chen J, Sethi A, Li QK, Chen L, Collins B, Gillet LC, Wollscheid B, Zhang H, Aebersold R: Glycoproteomic analysis of prostate cancer tissues by SWATH mass spectrometry discovers N-acylethanolamine acid amidase and protein tyrosine kinase 7 as signatures for tumor aggressiveness. Molecular & Cellular Proteomics 2014, 13:1753-1768. |
| 15 | Chen R, Seebun D, Ye M, Zou H, Figeys D: Site-specific characterization of cell membrane N-glycosylation with integrated hydrophilic interaction chromatography solid phase extraction and LC-MS/MS. Journal of Proteomics 2014, 103:194-203. |
| 22 | Nicastri A, Gaspari M, Sacco R, Elia L, Gabriele C, Romano R, Rizzuto A, Cuda G: N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue. Journal of Proteome Research 2014, 13:4932-4941. |
| 37 | Boersema PJ, Geiger T, Wisniewski JR, Mann M: Quantification of the N-glycosylated Secretome by Super-SILAC During Breast Cancer Progression and in Human Blood Samples. Molecular & Cellular Proteomics 2013, 12:158-171. |
| 43 | Wang GG, Wu YB, Zhou T, Guo YS, Zheng B, Wang J, Bi Y, Liu FJ, Zhou ZM, Guo XJ, Sha JH: Mapping of the N-Linked Glycoproteome of Human Spermatozoa. Journal of Proteome Research 2013, 12:5750-5759. |
| 54 | Tian Y, Yao Z, Roden R, Zhang H: Identification of glycoproteins associated with different histological subtypes of ovarian tumors using quantitative glycoproteomics. Proteomics 2011, 11:4677-4687. |
| 58 | Nagano K, Shinkawa T, Kato K, Inomata N, Yabuki N, Haramura M: Distinct cell surface proteome profiling by biotin labeling and glycoprotein capturing. Journal of Proteomics 2011, 74:1985-1993. |