Detail

UniProtKB-Q5T848


Protein	Probable G-protein coupled receptor 158
Gene	GPR158
Status	Reviewed
Source	LNCap/PC3 cell lines (Prostate cancer); Pancreatic islets; Serum; milk
Years	2008-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
143	YELAGLPGKWPALASAHPSLHRALDTLTHATNFLNVMLQSnK	2015(unpublished);
215	ILLQDLSSSAPHLAnATLETEWFHGLR	2015(2);
333	CHLnNSECMPIK	2012(48);
846	DQTEESSSLPTESQEEETTEnSTLESLSGK	2015(unpublished);
884	EDSEAESTESVPLVCKSASAHnLSSEK	2008(70);

Sequence

1	11	21	31	41	51	61	71	81	91
MGAMAYPLLL	CLLLAQLGLG	AVGASRDPQG	RPDSPRERTP	KGKPHAQQPG	RASASDSSAP	WSRSTDGTIL	AQKLAEEVPM	DVASYLYTGD	SHQLKRANCS
101	111	121	131	141	151	161	171	181	191
GRYELAGLPG	KWPALASAHP	SLHRALDTLT	HATNFLNVML	QSNKSREQNL	QDDLDWYQAL	VWSLLEGEPS	ISRAAITFST	DSLSAPAPQV	FLQATREESR
201	211	221	231	241	251	261	271	281	291
ILLQDLSSSA	PHLANATLET	EWFHGLRRKW	RPHLHRRGPN	QGPRGLGHSW	RRKDGLGGDK	SHFKWSPPYL	ECENGSYKPG	WLVTLSSAIY	GLQPNLVPEF
301	311	321	331	341	351	361	371	381	391
RGVMKVDINL	QKVDIDQCSS	DGWFSGTHKC	HLNNSECMPI	KGLGFVLGAY	ECICKAGFYH	PGVLPVNNFR	RRGPDQHISG	STKDVSEEAY	VCLPCREGCP
401	411	421	431	441	451	461	471	481	491
FCADDSPCFV	QEDKYLRLAI	ISFQALCMLL	DFVSMLVVYH	FRKAKSIRAS	GLILLETILF	GSLLLYFPVV	ILYFEPSTFR	CILLRWARLL	GFATVYGTVT
501	511	521	531	541	551	561	571	581	591
LKLHRVLKVF	LSRTAQRIPY	MTGGRVMRML	AVILLVVFWF	LIGWTSSVCQ	NLEKQISLIG	QGKTSDHLIF	NMCLIDRWDY	MTAVAEFLFL	LWGVYLCYAV
601	611	621	631	641	651	661	671	681	691
RTVPSAFHEP	RYMAVAVHNE	LIISAIFHTI	RFVLASRLQS	DWMLMLYFAH	THLTVTVTIG	LLLIPKFSHS	SNNPRDDIAT	EAYEDELDMG	RSGSYLNSSI
701	711	721	731	741	751	761	771	781	791
NSAWSEHSLD	PEDIRDELKK	LYAQLEIYKR	KKMITNNPHL	QKKRCSKKGL	GRSIMRRITE	IPETVSRQCS	KEDKEGADHG	TAKGTALIRK	NPPESSGNTG
801	811	821	831	841	851	861	871	881	891
KSKEETLKNR	VFSLKKSHST	YDHVRDQTEE	SSSLPTESQE	EETTENSTLE	SLSGKKLTQK	LKEDSEAEST	ESVPLVCKSA	SAHNLSSEKK	TGHPRTSMLQ
901	911	921	931	941	951	961	971	981	991
KSLSVIASAK	EKTLGLAGKT	QTAGVEERTK	SQKPLPKDKE	TNRNHSNSDN	TETKDPAPQN	SNPAEEPRKP	QKSGIMKQQR	VNPTTANSDL	NPGTTQMKDN
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
FDIGEVCPWE	VYDLTPGPVP	SESKVQKHVS	IVASEMEKNP	TFSLKEKSHH	KPKAAEVCQQ	SNQKRIDKAE	VCLWESQGQS	ILEDEKLLIS	KTPVLPERAK
1101	1111	1121	1131	1141	1151	1161	1171	1181	1191
EENGGQPRAA	NVCAGQSEEL	PPKAVASKTE	NENLNQIGHQ	EKKTSSSEEN	VRGSYNSSNN	FQQPLTSRAE	VCPWEFETPA	QPNAGRSVAL	PASSALSANK
1201	1211
IAGPRKEEIW	DSFKV

Reference

ID	Publication
2	Shah P, Wang X, Yang W, Eshghi ST, Sun S, Hoti N, Chen L, Yang S, Pasay J, Rubin A: Integrated Proteomic and Glycoproteomic Analyses of Prostate Cancer Cells Reveal Glycoprotein Alteration in Protein Abundance and Glycosylation. Molecular & Cellular Proteomics 2015, 14:2753-2763.
48	Danzer C, Eckhardt K, Schmidt A, Fankhauser N, Ribrioux S, Wollscheid B, Mueller L, Schiess R, Zuellig R, Lehmann R, et al: Comprehensive Description of the N-Glycoproteome of Mouse Pancreatic beta-Cells and Human Islets. Journal of Proteome Research 2012, 11:1598-1608.
70	Picariello G, Ferranti P, Mamone G, Roepstorff P, Addeo F: Identification of N-linked glycoproteins in human milk by hydrophilic interaction liquid chromatography and mass spectrometry. Proteomics 2008, 8:3833-3847.