Detail

UniProtKB-Q5VUB5


Protein	Protein FAM171A1
Gene	FAM171A1
Status	Reviewed
Source	22Rv1 cell line (prostate cancer); Colorectal tumor; LNCap/PC3 cell lines (Prostate cancer); Liver; Ovarian tumor; Pancreatic islets; Prostate tumor
Years	2009-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
159	LRLPEnTSYSD	2009(64);
159	RLPEnTSYSDL	2014(33);
159	RLPEnTSYSDLTAF	2014(33);
159	LPEnTSYSDLTAFLTAASSPSEVDSFPYLR	2015(2);
190	GLDGnGTGNSTR	2012(48); 2012(50); 2014(22); 2014(33); 2015(unpublished);2015(unpublished);
194	GLDGNGTGnSTR	2012(48); 2012(50); 2014(22); 2014(33); 2015(unpublished);2015(unpublished);

Sequence

1	11	21	31	41	51	61	71	81	91
MSRSATLLLC	LLGCHVWKAV	TKTLREPGAG	AQEVTLKVHI	SDASTHQPVA	DALIEIFTNQ	ASIASGTSGT	DGVAFIKFQY	KLGSQLIVTA	SKHAYVPNSA
101	111	121	131	141	151	161	171	181	191
PWKPIRLPVF	SSLSLGLLPE	RSATLMVYED	VVQIVSGFQG	ARPQPRVHFQ	RRALRLPENT	SYSDLTAFLT	AASSPSEVDS	FPYLRGLDGN	GTGNSTRHDL
201	211	221	231	241	251	261	271	281	291
TPVTAVSVHL	LSSNGTPVLV	DGPIYVTVPL	ATQSSLRHNA	YVAAWRFDQK	LGTWLKSGLG	LVHQEGSQLT	WTYIAPQLGY	WVAAMSPPIP	GPVVTQDITT
301	311	321	331	341	351	361	371	381	391
YHTVFLLAIL	GGMAFILLVL	LCLLLYYCRR	KCLKPRQHHR	KLQLPAGLES	SKRDQSTSMS	HINLLFSRRA	SEFPGPLSVT	SHGRPEAPGT	KELMSGVHLE
401	411	421	431	441	451	461	471	481	491
MMSPGGEGDL	HTPMLKLSYS	TSQEFSSREE	LLSCKEEDKS	QISFDNLTPS	GTLGKDYHKS	VEVFPLKARK	SMEREGYESS	GNDDYRGSYN	TVLSQPLFEK
501	511	521	531	541	551	561	571	581	591
QDREGPASTG	SKLTIQEHLY	PAPSSPEKEQ	LLDRRPTECM	MSRSVDHLER	PTSFPRPGQL	ICCSSVDQVN	DSVYRKVLPA	LVIPAHYMKL	PGDHSYVSQP
601	611	621	631	641	651	661	671	681	691
LVVPADQQLE	IERLQAELSN	PHAGIFPHPS	SQIQPQPLSS	QAISQQHLQD	AGTREWSPQN	ASMSESLSIP	ASLNDAALAQ	MNSEVQLLTE	KALMELGGGK
701	711	721	731	741	751	761	771	781	791
PLPHPRAWFV	SLDGRSNAHV	RHSYIDLQRA	GRNGSNDASL	DSGVDMNEPK	SARKGRGDAL	SLQQNYPPVQ	EHQQKEPRAP	DSTAYTQLVY	LDDVEQSGSE
801	811	821	831	841	851	861	871	881
CGTTVCTPED	SALRCLLEGS	SRRSGGQLPS	LQEETTRRTA	DAPSEPAASP	HQRRSAHEEE	EDDDDDDQGE	DKKSPWQKRE	ERPLMAFNIK

Reference

ID	Publication
2	Shah P, Wang X, Yang W, Eshghi ST, Sun S, Hoti N, Chen L, Yang S, Pasay J, Rubin A: Integrated Proteomic and Glycoproteomic Analyses of Prostate Cancer Cells Reveal Glycoprotein Alteration in Protein Abundance and Glycosylation. Molecular & Cellular Proteomics 2015, 14:2753-2763.
22	Nicastri A, Gaspari M, Sacco R, Elia L, Gabriele C, Romano R, Rizzuto A, Cuda G: N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue. Journal of Proteome Research 2014, 13:4932-4941.
33	Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.
48	Danzer C, Eckhardt K, Schmidt A, Fankhauser N, Ribrioux S, Wollscheid B, Mueller L, Schiess R, Zuellig R, Lehmann R, et al: Comprehensive Description of the N-Glycoproteome of Mouse Pancreatic beta-Cells and Human Islets. Journal of Proteome Research 2012, 11:1598-1608.
50	Whitmore TE, Peterson A, Holzman T, Eastham A, Amon L, McIntosh M, Ozinsky A, Nelson PS, Martin DB: Integrative Analysis of N-Linked Human Glycoproteomic Data Sets Reveals PTPRF Ectodomain as a Novel Plasma Biomarker Candidate for Prostate Cancer. Journal of Proteome Research 2012, 11:2653-2665.
64	Chen R, Jiang X, Sun D, Han G, Wang F, Ye M, Wang L, Zou H: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. J Proteome Res 2009, 8:651-661.