Detail

UniProtKB-Q68CR1


Protein	Protein sel-1 homolog 3
Gene	SEL1L3
Status	Reviewed
Source	Breast cancer xenografts; Colorectal tumor; DLBCL cell lines (Diffuse large B-cell lymphoma); LNCap/PC3 cell lines (Prostate cancer); OVCAR-3 cell line (Ovarian cancer); Ovarian tumor; Pancreatic islets
Years	2012-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
201	nYTIIQTIPPFERPFK	2014(16);
382	SYHnQTISFR	2014(16); 2014(22); 2015(unpublished);2015(2); 2015(unpublished);
394	nDTAGYFIIGGSR	2015(1);
394	EDFHYnDTAGYFIIGGSR	2014(16); 2015(unpublished);2015(1); 2015(2); 2015(unpublished);
527	nESVSEIGGK	2015(1);
527	NQnESVSEIGGK	2012(48); 2014(16); 2014(22); 2015(unpublished);2015(1); 2015(2); 2015(unpublished);
818	nQTIAGEYFHK	2014(16);
818	nQTLAGEYFHK	2015(unpublished);
937	YYnFSVFQIDAPSFAYLK	2015(2);

Sequence

1	11	21	31	41	51	61	71	81	91
MQRRGAGLGW	PRQQQQQPPP	LAVGPRAAAM	VPSGGVPQGL	GGRSACALLL	LCYLNVVPSL	GRQTSLTTSV	IPKAEQSVAY	KDFIYFTVFE	GNVRNVSEVS
101	111	121	131	141	151	161	171	181	191
VEYLCSQPCV	VNLEAVVSSE	FRSSIPVYKK	RWKNEKHLHT	SRTQIVHVKF	PSIMVYRDDY	FIRHSISVSA	VIVRAWITHK	YSGRDWNVKW	EENLLHAVAK
201	211	221	231	241	251	261	271	281	291
NYTLLQTIPP	FERPFKDHQV	CLEWNMGYIW	NLRANRIPQC	PLENDVVALL	GFPYASSGEN	TGIVKKFPRF	RNRELEATRR	QRMDYPVFTV	SLWLYLLHYC
301	311	321	331	341	351	361	371	381	391
KANLCGILYF	VDSNEMYGTP	SVFLTEEGYL	HIQMHLVKGE	DLAVKTKFII	PLKEWFRLDI	SFNGGQIVVT	TSIGQDLKSY	HNQTISFRED	FHYNDTAGYF
401	411	421	431	441	451	461	471	481	491
IIGGSRYVAG	IEGFFGPLKY	YRLRSLHPAQ	IFNPLLEKQL	AEQIKLYYER	CAEVQEIVSV	YASAAKHGGE	RQEACHLHNS	YLDLQRRYGR	PSMCRAFPWE
501	511	521	531	541	551	561	571	581	591
KELKDKHPSL	FQALLEMDLL	TVPRNQNESV	SEIGGKIFEK	AVKRLSSIDG	LHQISSIVPF	LTDSSCCGYH	KASYYLAVFY	ETGLNVPRDQ	LQGMLYSLVG
601	611	621	631	641	651	661	671	681	691
GQGSERLSSM	NLGYKHYQGI	DNYPLDWELS	YAYYSNIATK	TPLDQHTLQG	DQAYVETIRL	KDDEILKVQT	KEDGDVFMWL	KHEATRGNAA	AQQRLAQMLF
701	711	721	731	741	751	761	771	781	791
WGQQGVAKNP	EAAIEWYAKG	ALETEDPALI	YDYAIVLFKG	QGVKKNRRLA	LELMKKAASK	GLHQAVNGLG	WYYHKFKKNY	AKAAKYWLKA	EEMGNPDASY
801	811	821	831	841	851	861	871	881	891
NLGVLHLDGI	FPGVPGRNQT	LAGEYFHKAA	QGGHMEGTLW	CSLYYITGNL	ETFPRDPEKA	VVWAKHVAEK	NGYLGHVIRK	GLNAYLEGSW	HEALLYYVLA
901	911	921	931	941	951	961	971	981	991
AETGIEVSQT	NLAHICEERP	DLARRYLGVN	CVWRYYNFSV	FQIDAPSFAY	LKMGDLYYYG	HQNQSQDLEL	SVQMYAQAAL	DGDSQGFFNL	ALLIEEGTII
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
PHHILDFLEI	DSTLHSNNIS	ILQELYERCW	SHSNEESFSP	CSLAWLYLHL	RLLWGAILHS	ALIYFLGTFL	LSILIAWTVQ	YFQSVSASDP	PPRPSQASPD
1101	1111	1121	1131
TATSTASPAV	TPAADASDQD	QPTVTNNPEP	RG

Reference

ID	Publication
1	Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
2	Shah P, Wang X, Yang W, Eshghi ST, Sun S, Hoti N, Chen L, Yang S, Pasay J, Rubin A: Integrated Proteomic and Glycoproteomic Analyses of Prostate Cancer Cells Reveal Glycoprotein Alteration in Protein Abundance and Glycosylation. Molecular & Cellular Proteomics 2015, 14:2753-2763.
16	Deeb SJ, Cox J, Schmidt-Supprian M, Mann M: N-linked Glycosylation Enrichment for In-depth Cell Surface Proteomics of Diffuse Large B-cell Lymphoma Subtypes. Molecular & Cellular Proteomics 2014, 13:240-251.
22	Nicastri A, Gaspari M, Sacco R, Elia L, Gabriele C, Romano R, Rizzuto A, Cuda G: N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue. Journal of Proteome Research 2014, 13:4932-4941.
48	Danzer C, Eckhardt K, Schmidt A, Fankhauser N, Ribrioux S, Wollscheid B, Mueller L, Schiess R, Zuellig R, Lehmann R, et al: Comprehensive Description of the N-Glycoproteome of Mouse Pancreatic beta-Cells and Human Islets. Journal of Proteome Research 2012, 11:1598-1608.