Detail


Protein	Immunoglobulin superfamily member 10
Gene	IGSF10
Status	Reviewed
Source	Hela cell line (cervical cancer); Liver; OVCAR-3 cell line (Ovarian cancer); Prostate; Spermatozoa
Years	2013-2015

Site	Identified Peptides	Year(Publication ID)
949	LLLESVnTTNSHQTSVR	2015(12);
999	nSTVNIPLFR	2015(12);
1060	nVTCLSCLPR	2015(1);
1416	TLnLTDVIEELAQASTQTLK	2015(12);
1705	VQVIPnGTISIQR	2013(43);
1705	VQVLPnGTLSIQR	2015(12);
1783	nQTVVSESSQGSR	2015(1);
1998	IHVYPnGSLF	2014(33);
2195	nGSLTINK	2015(1);
2295	nGTLEIR	2014(14); 2015(12);
2295	ITVHKnGTLEIR	2015(12);
2358	STAInCSVDGNPPPEIIWIIPNGTR	2013(43);
2375	STAINCSVDGNPPPEIIWIIPnGTR	2013(43);
2393	nGSFIISK	2015(1);

Sequence

1	11	21	31	41	51	61	71	81	91
MKVKGRGITC	LLVSFAVICL	VATPGGKACP	RRCACYMPTE	VHCTFRYLTS	IPDSIPPNVE	RINLGYNSLV	RLMETDFSGL	TKLELLMLHS	NGIHTIPDKT
101	111	121	131	141	151	161	171	181	191
FSDLQALQVL	KMSYNKVRKL	QKDTFYGLRS	LTRLHMDHNN	IEFINPEVFY	GLNFLRLVHL	EGNQLTKLHP	DTFVSLSYLQ	IFKISFIKFL	YLSDNFLTSL
201	211	221	231	241	251	261	271	281	291
PQEMVSYMPD	LDSLYLHGNP	WTCDCHLKWL	SDWIQEKPDV	IKCKKDRSPS	SAQQCPLCMN	PRTSKGKPLA	MVSAAAFQCA	KPTIDSSLKS	KSLTILEDSS
301	311	321	331	341	351	361	371	381	391
SAFISPQGFM	APFGSLTLNM	TDQSGNEANM	VCSIQKPSRT	SPIAFTEEND	YIVLNTSFST	FLVCNIDYGH	IQPVWQILAL	YSDSPLILER	SHLLSETPQL
401	411	421	431	441	451	461	471	481	491
YYKYKQVAPK	PEDIFTNIEA	DLRADPSWLM	QDQISLQLNR	TATTFSTLQI	QYSSDAQITL	PRAEMRPVKH	KWTMISRDNN	TKLEHTVLVG	GTVGLNCPGQ
501	511	521	531	541	551	561	571	581	591
GDPTPHVDWL	LADGSKVRAP	YVSEDGRILI	DKSGKLELQM	ADSFDTGVYH	CISSNYDDAD	ILTYRITVVE	PLVEAYQENG	IHHTVFIGET	LDLPCHSTGI
601	611	621	631	641	651	661	671	681	691
PDASISWVIP	GNNVLYQSSR	DKKVLNNGTL	RILQVTPKDQ	GYYRCVAANP	SGVDFLIFQV	SVKMKGQRPL	EHDGETEGSG	LDESNPIAHL	KEPPGAQLRT
701	711	721	731	741	751	761	771	781	791
SALMEAEVGK	HTSSTSKRHN	YRELTLQRRG	DSTHRRFREN	RRHFPPSARR	IDPQHWAALL	EKAKKNAMPD	KRENTTVSPP	PVVTQLPNIP	GEEDDSSGML
801	811	821	831	841	851	861	871	881	891
ALHEEFMVPA	TKALNLPART	VTADSRTISD	SPMTNINYGT	EFSPVVNSQI	LPPEEPTDFK	LSTAIKTTAM	SKNINPTMSS	QIQGTTNQHS	STVFPLLLGA
901	911	921	931	941	951	961	971	981	991
TEFQDSDQMG	RGREHFQSRP	PITVRTMIKD	VNVKMLSSTT	NKLLLESVNT	TNSHQTSVRE	VSEPRHNHFY	SHTTQILSTS	TFPSDPHTAA	HSQFPIPRNS
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
TVNIPLFRRF	GRQRKIGGRG	RIISPYRTPV	LRRHRYSIFR	STTRGSSEKS	TTAFSATVLN	VTCLSCLPRE	RLTTATAALS	FPSAAPITFP	KADIARVPSE
1101	1111	1121	1131	1141	1151	1161	1171	1181	1191
ESTTLVQNPL	LLLENKPSVE	KTTPTIKYFR	TEISQVTPTG	AVMTYAPTSI	PMEKTHKVNA	SYPRVSSTNE	AKRDSVITSS	LSGAITKPPM	TIIAITRFSR
1201	1211	1221	1231	1241	1251	1261	1271	1281	1291
RKIPWQQNFV	NNHNPKGRLR	NQHKVSLQKS	TAVMLPKTSP	ALPRDKVSPF	HFTTLSTSVM	QIPSNTLTTA	HHTTTKTHNP	GSLPTKKELP	FPPLNPMLPS
1301	1311	1321	1331	1341	1351	1361	1371	1381	1391
IISKDSSTKS	IISTQTAIPA	TTPTFPASVI	TYETQTERSR	AQTIQREQEP	QKKNRTDPNI	SPDQSSGFTT	PTAMTPPVLT	TAETSVKPSV	SAFTHSPPEN
1401	1411	1421	1431	1441	1451	1461	1471	1481	1491
TTGISSTISF	HSRTLNLTDV	IEELAQASTQ	TLKSTIASET	TLSSKSHQST	TTRKAIIRHS	TIPPFLSSSA	TLMPVPISPP	FTQRAVTDNV	ATPISGLMTN
1501	1511	1521	1531	1541	1551	1561	1571	1581	1591
TVVKLHESSR	HNAKPQQLVA	EVATSPKVHP	NAKFTIGTTH	FIYSNLLHST	PMPALTTVKS	QNSKLTPSPW	AENQFWHKPY	SEIAEKGKKP	EVSMLATTGL
1601	1611	1621	1631	1641	1651	1661	1671	1681	1691
SEATTLVSDW	DGQKNTKKSD	FDKKPVQEAT	TSKLLPFDSL	SRYIFEKPRI	VGGKAASFTI	PANSDAFLPC	EAVGNPLPTI	HWTRVPSGLD	LSKRKQNSRV
1701	1711	1721	1731	1741	1751	1761	1771	1781	1791
QVLPNGTLSI	QRVEIQDRGQ	YLCSASNLFG	TDHLHVTLSV	VSYPPRILER	RTKEITVHSG	STVELKCRAE	GRPSPTVTWI	LANQTVVSES	SQGSRQAVVT
1801	1811	1821	1831	1841	1851	1861	1871	1881	1891
VDGTLVLHNL	SIYDRGFYKC	VASNPGGQDS	LLVKIQVIAA	PPVILEQRRQ	VIVGTWGESL	KLPCTAKGTP	QPSVYWVLSD	GTEVKPLQFT	NSKLFLFSNG
1901	1911	1921	1931	1941	1951	1961	1971	1981	1991
TLYIRNLASS	DRGTYECIAT	SSTGSERRVV	MLTMEERVTS	PRIEAASQKR	TEVNFGDKLL	LNCSATGEPK	PQIMWRLPSK	AVVDQQHRVG	SWIHVYPNGS
2001	2011	2021	2031	2041	2051	2061	2071	2081	2091
LFIGSVTEKD	SGVYLCVARN	KMGDDLILMH	VSLRLKPAKI	DHKQYFRKQV	LHGKDFQVDC	KASGSPVPEI	SWSLPDGTMI	NNAMQADDSG	HRTRRYTLFN
2101	2111	2121	2131	2141	2151	2161	2171	2181	2191
NGTLYFNKVG	VAEEGDYTCY	AQNTLGKDEM	KVHLTVITAA	PRIRQSNKTN	KRIKAGDTAV	LDCEVTGDPK	PKIFWLLPSN	DMISFSIDRY	TFHANGSLTI
2201	2211	2221	2231	2241	2251	2261	2271	2281	2291
NKVKLLDSGE	YVCVARNPSG	DDTKMYKLDV	VSKPPLINGL	YTNRTVIKAT	AVRHSKKHFD	CRAEGTPSPE	VMWIMPDNIF	LTAPYYGSRI	TVHKNGTLEI
2301	2311	2321	2331	2341	2351	2361	2371	2381	2391
RNVRLSDSAD	FICVARNEGG	ESVLVVQLEV	LEMLRRPTFR	NPFNEKIVAQ	LGKSTALNCS	VDGNPPPEII	WILPNGTRFS	NGPQSYQYLI	ASNGSFIISK
2401	2411	2421	2431	2441	2451	2461	2471	2481	2491
TTREDAGKYR	CAARNKVGYI	EKLVILEIGQ	KPVILTYAPG	TVKGISGESL	SLHCVSDGIP	KPNIKWTMPS	GYVVDRPQIN	GKYILHDNGT	LVIKEATAYD
2501	2511	2521	2531	2541	2551	2561	2571	2581	2591
RGNYICKAQN	SVGHTLITVP	VMIVAYPPRI	TNRPPRSIVT	RTGAAFQLHC	VALGVPKPEI	TWEMPDHSLL	STASKERTHG	SEQLHLQGTL	VIQNPQTSDS
2601	2611	2621
GIYKCTAKNP	LGSDYAATYI	QVI

Reference

ID	Publication
1	Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
12	Weng Y, Sui Z, Jiang H, Shan Y, Chen L, Zhang S, Zhang L, Zhang Y: Releasing N-glycan from Peptide N-terminus by N-terminal Succinylation Assisted Enzymatic Deglycosylation. Scientific Reports 2015, 5.
14	Liu Y, Chen J, Sethi A, Li QK, Chen L, Collins B, Gillet LC, Wollscheid B, Zhang H, Aebersold R: Glycoproteomic analysis of prostate cancer tissues by SWATH mass spectrometry discovers N-acylethanolamine acid amidase and protein tyrosine kinase 7 as signatures for tumor aggressiveness. Molecular & Cellular Proteomics 2014, 13:1753-1768.
33	Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.
43	Wang GG, Wu YB, Zhou T, Guo YS, Zheng B, Wang J, Bi Y, Liu FJ, Zhou ZM, Guo XJ, Sha JH: Mapping of the N-Linked Glycoproteome of Human Spermatozoa. Journal of Proteome Research 2013, 12:5750-5759.

UniProtKB-Q6WRI0

Glycosites

Sequence

Reference