Detail

Contains

UniProtKB-Q7Z553


Protein	MAM domain-containing glycosylphosphatidylinositol anchor protein 2
Gene	MDGA2
Status	Reviewed
Source	Breast cancer xenografts; Cerebrospinal fluid; HEK293 cell line (embryonic kidney); Platelet; Prostate; Prostate tumor
Years	2007-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
92	FQDSSVFnETLR	2014(14);
213	NLRPQDYAnYSCIASVR	2014(15);
237	NVCNIPDKMVSFRLSnK	2015(unpublished);
504	LVnVSR	2015(unpublished);
703	GELITYnLTELIKPEAYEVR	2007(unpublished);2007(unpublished);

Sequence

1	11	21	31	41	51	61	71	81	91
MDLLYGLVWL	LTVLLEGISG	QGVYAPPTVR	IVHSGLACNI	EEERYSERVY	TIREGETLEL	TCLVTGHPRP	QIRWTKTAGS	ASDRFQDSSV	FNETLRITNI
101	111	121	131	141	151	161	171	181	191
QRHQGGRYYC	KAENGLGSPA	IKSIRVDVYY	LDDPVVTVHQ	SIGEAKEQFY	YERTVFLRCV	ANSNPPVRYS	WRRGQEVLLQ	GSDKGVEIYE	PFFTQGETKI
201	211	221	231	241	251	261	271	281	291
LKLKNLRPQD	YANYSCIASV	RNVCNIPDKM	VSFRLSNKTA	SPSIKLLVDD	PIVVNPGEAI	TLVCVTTGGE	PAPSLTWVRS	FGTLPEKTVL	NGGTLTIPAI
301	311	321	331	341	351	361	371	381	391
TSDDAGTYSC	IANNNVGNPA	KKSTNIIVRA	LKKGRFWITP	DPYHKDDNIQ	IGREVKISCQ	VEAVPSEELT	FSWFKNGRPL	RSSERMVITQ	TDPDVSPGTT
401	411	421	431	441	451	461	471	481	491
NLDIIDLKFT	DFGTYTCVAS	LKGGGISDIS	IDVNISSSTV	PPNLTVPQEK	SPLVTREGDT	IELQCQVTGK	PKPIILWSRA	DKEVAMPDGS	MQMESYDGTL
501	511	521	531	541	551	561	571	581	591
RIVNVSREMS	GMYRCQTSQY	NGFNVKPREA	LVQLIVQYPP	AVEPAFLEIR	QGQDRSVTMS	CRVLRAYPIR	VLTYEWRLGN	KLLRTGQFDS	QEYTEYAVKS
601	611	621	631	641	651	661	671	681	691
LSNENYGVYN	CSIINEAGAG	RCSFLVTGKA	YAPEFYYDTY	NPVWQNRHRV	YSYSLQWTQM	NPDAVDRIVA	YRLGIRQAGQ	QRWWEQEIKI	NGNIQKGELI
701	711	721	731	741	751	761	771	781	791
TYNLTELIKP	EAYEVRLTPL	TKFGEGDSTI	RVIKYSAPVN	PHLREFHCGF	EDGNICLFTQ	DDTDNFDWTK	QSTATRNTKY	TPNTGPNADR	SGSKEGFYMY
801	811	821	831	841	851	861	871	881	891
IETSRPRLEG	EKARLLSPVF	SIAPKNPYGP	TNTAYCFSFF	YHMYGQHIGV	LNVYLRLKGQ	TTIENPLWSS	SGNKGQRWNE	AHVNIYPITS	FQLIFEGIRG
901	911	921	931	941	951
PGIEGDIAID	DVSIAEGECA	KQDLATKNSV	DGAVGILVHI	WLFPIIVLIS	ILSPRR

Reference

ID	Publication
14	Liu Y, Chen J, Sethi A, Li QK, Chen L, Collins B, Gillet LC, Wollscheid B, Zhang H, Aebersold R: Glycoproteomic analysis of prostate cancer tissues by SWATH mass spectrometry discovers N-acylethanolamine acid amidase and protein tyrosine kinase 7 as signatures for tumor aggressiveness. Molecular & Cellular Proteomics 2014, 13:1753-1768.
15	Chen R, Seebun D, Ye M, Zou H, Figeys D: Site-specific characterization of cell membrane N-glycosylation with integrated hydrophilic interaction chromatography solid phase extraction and LC-MS/MS. Journal of Proteomics 2014, 103:194-203.