| Protein | Scavenger receptor cysteine-rich type 1 protein M130 |
| Gene | CD163 |
| Status | Reviewed |
| Source | Breast tumor; Colorectal tumor; Human; Liver; Liver tumor (HCC); Ovarian tumor; Pancreatic islets; Plasma; Prostate; Prostate tumor; Serum; Serum (HCC); Urine; ovarian tumor; plasma |
| Years | 2005-2015 |
| Site | Identified Peptides | Year(Publication ID) |
|---|---|---|
| 105 | IKAPGWAnSS | 2009(64); |
| 105 | AnSSAGSGRIW | 2014(33); |
| 105 | GWAnSSAGSGR | 2014(33); 2015(unpublished); |
| 105 | APGWAnSSAGSGR | 2005( 81); 2007(66); 2009(54); 2011(3); 2012(48); 2012(42); 2013(45); 2013(45); 2013(14); 2014(22); 2014(32); 2014(33); 2014(10); 2015(unpublished);2015(unpublished);2015(unpublished);2015(unpublished);2015(unpublished);2015;2007;2007;2007;2007;2007; |
| 105 | KAPGWAnSSAGSGRIW | 2014(33); |
| 105 | AIKAPGWAnSSAGSGRIW | 2014(33); |
| 105 | AVSVICNQLGCPTAIKAPGWAnSSAGSGR | 2014(33); |
| 123 | GnESAIWDCK | 2014(32); 2014(32); |
| 123 | GnESALWDCK | 2013(42); 2013(45); 2013(45); 2014(22); 2014(33); 2015(unpublished);2015(unpublished);2015(unpublished);2015(unpublished);2015(unpublished);2015(8); 2015(10); |
| 123 | IWMDHVSCRGnE | 2014(33); |
| 123 | MDHVSCRGnESALW | 2014(33); |
| 123 | GnESALWDCKHDGWGK | 2013(38); 2013(45); 2014(33); |
| 140 | HSnCTHQQDAGVTCSDGSNLE | 2014(33); |
| 140 | HSnCTHQQDAGVTCSDGSNLEMR | 2007(64); 2009(3); 2012(42); 2013(45); 2013(13); 2014(14); 2014(22); 2014(33); 2014(10); 2015(unpublished);2015(unpublished);2015(unpublished);2015(unpublished);2007;2007;2007;2007; |
| 231 | GnESALWNCK | 2014(33); |
| 231 | GSGPIWFDDLICNGnE | 2014(33); |
| 320 | AIGRVnASKGF | 2014(33); |
| 320 | GCPTAVTAIGRVnASKGF | 2014(33); |
| 320 | QLGCPTAVTAIGRVnASK | 2014(33); |
| 320 | DAAVACKQLGCPTAVTAIGRVnASKGF | 2014(33); |
| 445 | LSSCNGnETSLW | 2014(33); |
| 445 | FLSSCNGnETSLW | 2014(33); |
| 445 | LFLSSCNGnETSLW | 2014(33); |
| 445 | SSCNGnETSLWDCK | 2014(33); |
| 445 | LSSCNGnETSLWDCK | 2014(33); |
| 445 | LFLSSCNGnETSLWDCK | 2014(33); |
| 445 | IQATNTWIFISSCNGnETSIWDCK | 2014(32); 2014(32); |
| 445 | IQATNTWLFLSSCNGnETSLWDCK | 2015(unpublished);2015(unpublished); |
| 685 | VICSGnQSQTL | 2014(33); |
| 685 | SVICSGnQSQTL | 2014(33); |
| 685 | GASLCPSEQVASVICSGnQSQTL | 2014(33); |
| 767 | AInATGSAHF | 2014(33); |
| 767 | AInATGSAHFGE | 2014(33); |
| 767 | GCGEAInATGSAHF | 2014(33); |
| 767 | QLGCGEAInATGSAH | 2014(33); |
| 767 | QLGCGEAInATGSAHF | 2014(33); |
| 767 | RQLGCGEAInATGSAHF | 2014(33); |
| 767 | AInATGSAHFGEGTGPIWLDE | 2014(33); |
| 767 | QIGCGEAInATGSAHFGEGTGPIWIDEMK | 2014(32); 2014(32); |
| 767 | QLGCGEAInATGSAHFGEGTGPIWLDEMK | 2009(64); 2014(33); 2015(unpublished);2015(10); |
| 1001 | CKGnESSLW | 2014(33); |
| 1001 | GnESSLWDCPAR | 2014(22); 2014(33); 2015(unpublished);2015(10); |
| 1001 | NEVKCKGnESSLW | 2014(33); |
| 1001 | CKGnESSLWDCPAR | 2014(33); 2015(unpublished);2015(8); |
| 1027 | VnCTDISVQK | 2014(33); |
| 1027 | DAAVnCTDISVQ | 2014(33); |
| 1027 | DAAVnCTDISVQK | 2014(33); |
| 1027 | EDAAVnCTDISVQK | 2009(64); 2010(40); 2011(54); 2012(3); 2012(48); 2013(34); 2014(13); 2014(14); 2014(22); 2014(32); 2014(32); 2014(33); 2015(unpublished);2015(unpublished);2015(unpublished);2007(unpublished);2007;2007;2007; |
| 1027 | DAAVnCTDISVQKTPQK | 2014(33); |
| 1027 | EDAAVnCTDISVQKTPQK | 2014(33); |
| 1027 | ECGHKEDAAVnCTDISVQKT | 2015(6); |
| 1027 | GHSECGHKEDAAVnCTDISVQ | 2014(33); |
| 1027 | WGHSECGHKEDAAVnCTDISVQK | 2013(42); 2014(33); 2015(unpublished); |
| 1027 | RWGHSECGHKEDAAVnCTDISVQK | 2014(33); |
| 1112 | EMNSCLNADDLDLMnSSENSHESADFSAAELISVSK | 2015(unpublished); |
| 1 | 11 | 21 | 31 | 41 | 51 | 61 | 71 | 81 | 91 |
| MSKLRMVLLE | DSGSADFRRH | FVNLSPFTIT | VVLLLSACFV | TSSLGGTDKE | LRLVDGENKC | SGRVEVKVQE | EWGTVCNNGW | SMEAVSVICN | QLGCPTAIKA |
| 101 | 111 | 121 | 131 | 141 | 151 | 161 | 171 | 181 | 191 |
| PGWANSSAGS | GRIWMDHVSC | RGNESALWDC | KHDGWGKHSN | CTHQQDAGVT | CSDGSNLEMR | LTRGGNMCSG | RIEIKFQGRW | GTVCDDNFNI | DHASVICRQL |
| 201 | 211 | 221 | 231 | 241 | 251 | 261 | 271 | 281 | 291 |
| ECGSAVSFSG | SSNFGEGSGP | IWFDDLICNG | NESALWNCKH | QGWGKHNCDH | AEDAGVICSK | GADLSLRLVD | GVTECSGRLE | VRFQGEWGTI | CDDGWDSYDA |
| 301 | 311 | 321 | 331 | 341 | 351 | 361 | 371 | 381 | 391 |
| AVACKQLGCP | TAVTAIGRVN | ASKGFGHIWL | DSVSCQGHEP | AIWQCKHHEW | GKHYCNHNED | AGVTCSDGSD | LELRLRGGGS | RCAGTVEVEI | QRLLGKVCDR |
| 401 | 411 | 421 | 431 | 441 | 451 | 461 | 471 | 481 | 491 |
| GWGLKEADVV | CRQLGCGSAL | KTSYQVYSKI | QATNTWLFLS | SCNGNETSLW | DCKNWQWGGL | TCDHYEEAKI | TCSAHREPRL | VGGDIPCSGR | VEVKHGDTWG |
| 501 | 511 | 521 | 531 | 541 | 551 | 561 | 571 | 581 | 591 |
| SICDSDFSLE | AASVLCRELQ | CGTVVSILGG | AHFGEGNGQI | WAEEFQCEGH | ESHLSLCPVA | PRPEGTCSHS | RDVGVVCSRY | TEIRLVNGKT | PCEGRVELKT |
| 601 | 611 | 621 | 631 | 641 | 651 | 661 | 671 | 681 | 691 |
| LGAWGSLCNS | HWDIEDAHVL | CQQLKCGVAL | STPGGARFGK | GNGQIWRHMF | HCTGTEQHMG | DCPVTALGAS | LCPSEQVASV | ICSGNQSQTL | SSCNSSSLGP |
| 701 | 711 | 721 | 731 | 741 | 751 | 761 | 771 | 781 | 791 |
| TRPTIPEESA | VACIESGQLR | LVNGGGRCAG | RVEIYHEGSW | GTICDDSWDL | SDAHVVCRQL | GCGEAINATG | SAHFGEGTGP | IWLDEMKCNG | KESRIWQCHS |
| 801 | 811 | 821 | 831 | 841 | 851 | 861 | 871 | 881 | 891 |
| HGWGQQNCRH | KEDAGVICSE | FMSLRLTSEA | SREACAGRLE | VFYNGAWGTV | GKSSMSETTV | GVVCRQLGCA | DKGKINPASL | DKAMSIPMWV | DNVQCPKGPD |
| 901 | 911 | 921 | 931 | 941 | 951 | 961 | 971 | 981 | 991 |
| TLWQCPSSPW | EKRLASPSEE | TWITCDNKIR | LQEGPTSCSG | RVEIWHGGSW | GTVCDDSWDL | DDAQVVCQQL | GCGPALKAFK | EAEFGQGTGP | IWLNEVKCKG |
| 1001 | 1011 | 1021 | 1031 | 1041 | 1051 | 1061 | 1071 | 1081 | 1091 |
| NESSLWDCPA | RRWGHSECGH | KEDAAVNCTD | ISVQKTPQKA | TTGRSSRQSS | FIAVGILGVV | LLAIFVALFF | LTKKRRQRQR | LAVSSRGENL | VHQIQYREMN |
| 1101 | 1111 | 1121 | 1131 | 1141 | 1151 | ||||
| SCLNADDLDL | MNSSENSHES | ADFSAAELIS | VSKFLPISGM | EKEAILSHTE | KENGNL |
| ID | Publication |
|---|---|
| 3 | Tian Y, Almaraz RT, Choi CH, Li QK, Saeui C, Li D, Shah P, Bhattacharya R, Yarema KJ, Zhang H: Identification of sialylated glycoproteins from metabolically oligosaccharide engineered pancreatic cells. Clinical proteomics 2015, 12:11. |
| 6 | Kim DS, Hahn Y: The acquisition of novel N-glycosylation sites in conserved proteins during human evolution. Bmc Bioinformatics 2015, 16. |
| 8 | Ma C, Zhang Q, Qu JY, Zhao XY, Li X, Liu YP, Wang PG: A precise approach in large scale core-fucosylated glycoprotein identification with low- and high-normalized collision energy. Journal of Proteomics 2015, 114:61-70. |
| 10 | Tan ZJ, Yin HD, Nie S, Lin ZX, Zhu JH, Ruffin MT, Anderson MA, Simone DM, Lubman DM: Large-Scale Identification of Core-Fucosylated Glycopeptide Sites in Pancreatic Cancer Serum Using Mass Spectrometry. Journal of Proteome Research 2015, 14:1968-1978. |
| 13 | Yang W, Laeyendecker O, Wendel SK, Zhang B, Sun S, Zhou J-Y, Ao M, Moore RD, Jackson JB, Zhang H: Glycoproteomic Study Reveals Altered Plasma Proteins Associated with HIV Elite Suppressors. Theranostics 2014, 4:1153. |
| 14 | Liu Y, Chen J, Sethi A, Li QK, Chen L, Collins B, Gillet LC, Wollscheid B, Zhang H, Aebersold R: Glycoproteomic analysis of prostate cancer tissues by SWATH mass spectrometry discovers N-acylethanolamine acid amidase and protein tyrosine kinase 7 as signatures for tumor aggressiveness. Molecular & Cellular Proteomics 2014, 13:1753-1768. |
| 22 | Nicastri A, Gaspari M, Sacco R, Elia L, Gabriele C, Romano R, Rizzuto A, Cuda G: N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue. Journal of Proteome Research 2014, 13:4932-4941. |
| 32 | Zhang Z, Sun Z, Zhu J, Liu J, Huang G, Ye M, Zou H: High-Throughput Determination of the Site-Specific N-Sialoglycan Occupancy Rates by Differential Oxidation of Glycoproteins Followed with Quantitative Glycoproteomics Analysis. Analytical Chemistry 2014, 86:9830-9837. |
| 33 | Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721. |
| 34 | Sun S, Zhang B, Aiyetan P, Zhou J-Y, Shah P, Yang W, Levine DA, Zhang Z, Chan DW, Zhang H: Analysis of N-glycoproteins using Genomic N-glycosite Prediction. Journal of Proteome Research 2013, 12:5609-5615. |
| 38 | Kaji H, Ocho M, Togayachi A, Kuno A, Sogabe M, Ohkura T, Nozaki H, Angata T, Chiba Y, Ozaki H, et al: Glycoproteomic Discovery of Serological Biomarker Candidates for HCV/HBV Infection-Associated Liver Fibrosis and Hepatocellular Carcinoma. Journal of Proteome Research 2013, 12:2630-2640. |
| 40 | Li X, Jiang J, Zhao X, Wang J, Han H, Zhao Y, Peng B, Zhong R, Ying W, Qian X: N-glycoproteome Analysis of the Secretome of Human Metastatic Hepatocellular Carcinoma Cell Lines Combining Hydrazide Chemistry, HILIC Enrichment and Mass Spectrometry. Plos One 2013, 8. |
| 42 | Ma C, Zhao X, Han H, Tong W, Zhang Q, Qin P, Chang C, Peng B, Ying W, Qian X: N-linked glycoproteome profiling of human serum using tandem enrichment and multiple fraction concatenation. Electrophoresis 2013, 34:2440-2450. |
| 45 | Zhou H, Froehlich JW, Briscoe AC, Lee RS: The GlycoFilter: A Simple and Comprehensive Sample Preparation Platform for Proteomics, N-Glycomics and Glycosylation Site Assignment. Molecular & Cellular Proteomics 2013, 12:2981-2991. |
| 48 | Danzer C, Eckhardt K, Schmidt A, Fankhauser N, Ribrioux S, Wollscheid B, Mueller L, Schiess R, Zuellig R, Lehmann R, et al: Comprehensive Description of the N-Glycoproteome of Mouse Pancreatic beta-Cells and Human Islets. Journal of Proteome Research 2012, 11:1598-1608. |
| 54 | Tian Y, Yao Z, Roden R, Zhang H: Identification of glycoproteins associated with different histological subtypes of ovarian tumors using quantitative glycoproteomics. Proteomics 2011, 11:4677-4687. |
| 64 | Chen R, Jiang X, Sun D, Han G, Wang F, Ye M, Wang L, Zou H: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. J Proteome Res 2009, 8:651-661. |
| 66 | Jia W, Lu Z, Fu Y, Wang H-P, Wang L-H, Chi H, Yuan Z-F, Zheng Z-B, Song L-N, Han H-H, et al: A Strategy for Precise and Large Scale Identification of Core Fucosylated Glycoproteins. Molecular & Cellular Proteomics 2009, 8:913-923. |