Detail

UniProtKB-Q8IUL8


Protein	Cartilage intermediate layer protein 2
Gene	CILP2
Status	Reviewed
Source	Breast Cancer cell lines; Breast cancer xenografts; DLBCL cell lines (Diffuse large B-cell lymphoma); Ovarian tumor; Prostate
Years	2013-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
308	EAGQnVTFCCK	2014(14); 2014(16);
308	VREAGQnVTFCCK	2013(37);
329	YSWFHnGTLLDR	2015(unpublished);2015(unpublished);
329	KYSWFHnGTIIDR	2013(37);

Sequence

1	11	21	31	41	51	61	71	81	91
MASLLPLLCL	CVVAAHLAGA	RDATPTEEPM	ATALGLERRS	VYTGQPSPAL	EDWEEASEWT	SWFNVDHPGG	DGDFESLAAI	RFYYGPARVC	PRPLALEART
101	111	121	131	141	151	161	171	181	191
TDWALPSAVG	ERVHLNPTRG	FWCLNREQPR	GRRCSNYHVR	FRCPLEASWG	AWGPWGPCSG	SCGPGRRLRR	RHCPSPAGDA	CPGRPLEAQK	CVRPRCPGCS
201	211	221	231	241	251	261	271	281	291
LDTCECPDHI	LLGSVVTPSG	QPLLGARVSL	RDQPGTVATS	DAHGTFRVPG	VCADSRANIR	AQMDGFSAGE	AQAQANGSIS	VVTIILDKLE	KPYLVKHPES
301	311	321	331	341	351	361	371	381	391
RVREAGQNVT	FCCKASGTPM	PKKYSWFHNG	TLLDRRAHGY	GAHLELRGLR	PDQAGIYHCK	AWNEAGAVRS	GTARLTVLAP	GQPACDPRPR	EYLIKLPEDC
401	411	421	431	441	451	461	471	481	491
GQPGSGPAYL	DVGLCPDTRC	PSLAGSSPRC	GDASSRCCSV	RRLERREIHC	PGYVLPVKVV	AECGCQKCLP	PRGLVRGRVV	AADSGEPLRF	ARILLGQEPI
501	511	521	531	541	551	561	571	581	591
GFTAYQGDFT	IEVPPSTQRL	VVTFVDPSGE	FMDAVRVLPF	DPRGAGVYHE	VKAMRKKAPV	ILHTSQSNTI	PLGELEDEAP	LGELVLPSGA	FRRADGKPYS
601	611	621	631	641	651	661	671	681	691
GPVEARVTFV	DPRDLTSAAS	APSDLRFVDS	DGELAPLRTY	GMFSVDLRAP	GSAEQLQVGP	VAVRVAASQI	HMPGHVEALK	LWSLNPETGL	WEEESGFRRE
701	711	721	731	741	751	761	771	781	791
GSSGPRVRRE	ERVFLVGNVE	IRERRLFNLD	VPERRRCFVK	VRAYANDKFT	PSEQVEGVVV	TLVNLEPAPG	FSANPRAWGR	FDSAVTGPNG	ACLPAFCDAD
801	811	821	831	841	851	861	871	881	891
RPDAYTALVT	ATLGGEELEP	APSLPRPLPA	TVGVTQPYLD	RLGYRRTDHD	DPAFKRNGFR	INLAKPRPGD	PAEANGPVYP	WRSLRECQGA	PVTASHFRFA
901	911	921	931	941	951	961	971	981	991
RVEADKYEYN	VVPFREGTPA	SWTGDLLAWW	PNPQEFRACF	LKVKIQGPQE	YMVRSHNAGG	SHPRTRGQLY	GLRDARSVRD	PERPGTSAAC	VEFKCSGMLF
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
DQRQVDRTLV	TIMPQGSCRR	VAVNGLLRDY	LTRHPPPVPA	EDPAAFSMLA	PLDPLGHNYG	VYTVTDQSPR	LAKEIAIGRC	FDGSSDGFSR	EMKADAGTAV
1101	1111	1121	1131	1141	1151
TFQCREPPAG	RPSLFQRLLE	SPATALGDIR	REMSEAAQAQ	ARASGPLRTR	RGRVRQ

Reference

ID	Publication
14	Liu Y, Chen J, Sethi A, Li QK, Chen L, Collins B, Gillet LC, Wollscheid B, Zhang H, Aebersold R: Glycoproteomic analysis of prostate cancer tissues by SWATH mass spectrometry discovers N-acylethanolamine acid amidase and protein tyrosine kinase 7 as signatures for tumor aggressiveness. Molecular & Cellular Proteomics 2014, 13:1753-1768.
16	Deeb SJ, Cox J, Schmidt-Supprian M, Mann M: N-linked Glycosylation Enrichment for In-depth Cell Surface Proteomics of Diffuse Large B-cell Lymphoma Subtypes. Molecular & Cellular Proteomics 2014, 13:240-251.
37	Boersema PJ, Geiger T, Wisniewski JR, Mann M: Quantification of the N-glycosylated Secretome by Super-SILAC During Breast Cancer Progression and in Human Blood Samples. Molecular & Cellular Proteomics 2013, 12:158-171.