Detail

UniProtKB-Q8IZJ1


Protein	Netrin receptor UNC5B
Gene	UNC5B
Status	Reviewed
Source	Breast Cancer cell lines; Breast cancer xenografts; Colorectal cancer cell line, HCT-116 (colorectal cancer)Jurkat T cell line; Colorectal tumor; HEK293 cell line (embryonic kidney); Liver; OVCAR-3 cell line (Ovarian cancer); Ovarian tumor; Prostate tumor; Urine
Years	2007-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
222	LSDTAnYTCVAK	2011(58); 2014(13); 2014(15); 2014(22); 2014(33); 2015(unpublished);2015(unpublished);2015;2015;2007;2007;
222	RISDTAnYTCVAK	2013(37);
347	nCTDGLCMQNK	2015(1); 2015(unpublished);2007(unpublished);2007;

Sequence

1	11	21	31	41	51	61	71	81	91
MGARSGARGA	LLLALLLCWD	PRLSQAGTDS	GSEVLPDSFP	SAPAEPLPYF	LQEPQDAYIV	KNKPVELRCR	AFPATQIYFK	CNGEWVSQND	HVTQEGLDEA
101	111	121	131	141	151	161	171	181	191
TGLRVREVQI	EVSRQQVEEL	FGLEDYWCQC	VAWSSAGTTK	SRRAYVRIAY	LRKNFDQEPL	GKEVPLDHEV	LLQCRPPEGV	PVAEVEWLKN	EDVIDPTQDT
201	211	221	231	241	251	261	271	281	291
NFLLTIDHNL	IIRQARLSDT	ANYTCVAKNI	VAKRRSTTAT	VIVYVNGGWS	SWAEWSPCSN	RCGRGWQKRT	RTCTNPAPLN	GGAFCEGQAF	QKTACTTICP
301	311	321	331	341	351	361	371	381	391
VDGAWTEWSK	WSACSTECAH	WRSRECMAPP	PQNGGRDCSG	TLLDSKNCTD	GLCMQNKKTL	SDPNSHLLEA	SGDAALYAGL	VVAIFVVVAI	LMAVGVVVYR
401	411	421	431	441	451	461	471	481	491
RNCRDFDTDI	TDSSAALTGG	FHPVNFKTAR	PSNPQLLHPS	VPPDLTASAG	IYRGPVYALQ	DSTDKIPMTN	SPLLDPLPSL	KVKVYSSSTT	GSGPGLADGA
501	511	521	531	541	551	561	571	581	591
DLLGVLPPGT	YPSDFARDTH	FLHLRSASLG	SQQLLGLPRD	PGSSVSGTFG	CLGGRLSIPG	TGVSLLVPNG	AIPQGKFYEM	YLLINKAEST	LPLSEGTQTV
601	611	621	631	641	651	661	671	681	691
LSPSVTCGPT	GLLLCRPVIL	TMPHCAEVSA	RDWIFQLKTQ	AHQGHWEEVV	TLDEETLNTP	CYCQLEPRAC	HILLDQLGTY	VFTGESYSRS	AVKRLQLAVF
701	711	721	731	741	751	761	771	781	791
APALCTSLEY	SLRVYCLEDT	PVALKEVLEL	ERTLGGYLVE	EPKPLMFKDS	YHNLRLSLHD	LPHAHWRSKL	LAKYQEIPFY	HIWSGSQKAL	HCTFTLERHS
801	811	821	831	841	851	861	871	881	891
LASTELTCKI	CVRQVEGEGQ	IFQLHTTLAE	TPAGSLDTLC	SAPGSTVTTQ	LGPYAFKIPL	SIRQKICNSL	DAPNSRGNDW	RMLAQKLSMD	RYLNYFATKA
901	911	921	931	941
SPTGVILDLW	EALQQDDGDL	NSLASALEEM	GKSEMLVAVA	TDGDC

Reference

ID	Publication
1	Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
13	Yang W, Laeyendecker O, Wendel SK, Zhang B, Sun S, Zhou J-Y, Ao M, Moore RD, Jackson JB, Zhang H: Glycoproteomic Study Reveals Altered Plasma Proteins Associated with HIV Elite Suppressors. Theranostics 2014, 4:1153.
15	Chen R, Seebun D, Ye M, Zou H, Figeys D: Site-specific characterization of cell membrane N-glycosylation with integrated hydrophilic interaction chromatography solid phase extraction and LC-MS/MS. Journal of Proteomics 2014, 103:194-203.
22	Nicastri A, Gaspari M, Sacco R, Elia L, Gabriele C, Romano R, Rizzuto A, Cuda G: N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue. Journal of Proteome Research 2014, 13:4932-4941.
33	Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.
37	Boersema PJ, Geiger T, Wisniewski JR, Mann M: Quantification of the N-glycosylated Secretome by Super-SILAC During Breast Cancer Progression and in Human Blood Samples. Molecular & Cellular Proteomics 2013, 12:158-171.
58	Nagano K, Shinkawa T, Kato K, Inomata N, Yabuki N, Haramura M: Distinct cell surface proteome profiling by biotin labeling and glycoprotein capturing. Journal of Proteomics 2011, 74:1985-1993.