Detail

UniProtKB-Q8IZY2


Protein	ATP-binding cassette sub-family A member 7
Gene	ABCA7
Status	Reviewed
Source	DLBCL cell lines (Diffuse large B-cell lymphoma); Hela cell line (cervical cancer); LNCap/PC3 cell lines (Prostate cancer); Liver; Ovarian tumor; Platelet; Urine
Years	2007-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
98	ISNFnDSIVSR	2014(16);
98	LSNFnDSLVSR	2014(33); 2015(unpublished);2015(2); 2015(12);
98	LSNFnDSLVSRLLADA	2007(unpublished);
312	KIMAQVnR	2014(16);
340	IFTFMnDSSNVAMIQR	2014(16);
340	EVWEMLGPRIFTFMnDSSNVAMLQR	2015(12);
1335	VIASGnWTPESPSPACQCSRPGAR	2014(16);
1518	NHPLnLTK	2015(unpublished);
1518	HAHSITTINHPInITK	2014(16);

Sequence

1	11	21	31	41	51	61	71	81	91
MAFWTQLMLL	LWKNFMYRRR	QPVQLLVELL	WPLFLFFILV	AVRHSHPPLE	HHECHFPNKP	LPSAGTVPWL	QGLICNVNNT	CFPQLTPGEE	PGRLSNFNDS
101	111	121	131	141	151	161	171	181	191
LVSRLLADAR	TVLGGASAHR	TLAGLGKLIA	TLRAARSTAQ	PQPTKQSPLE	PPMLDVAELL	TSLLRTESLG	LALGQAQEPL	HSLLEAAEDL	AQELLALRSL
201	211	221	231	241	251	261	271	281	291
VELRALLQRP	RGTSGPLELL	SEALCSVRGP	SSTVGPSLNW	YEASDLMELV	GQEPESALPD	SSLSPACSEL	IGALDSHPLS	RLLWRRLKPL	ILGKLLFAPD
301	311	321	331	341	351	361	371	381	391
TPFTRKLMAQ	VNRTFEELTL	LRDVREVWEM	LGPRIFTFMN	DSSNVAMLQR	LLQMQDEGRR	QPRPGGRDHM	EALRSFLDPG	SGGYSWQDAH	ADVGHLVGTL
401	411	421	431	441	451	461	471	481	491
GRVTECLSLD	KLEAAPSEAA	LVSRALQLLA	EHRFWAGVVF	LGPEDSSDPT	EHPTPDLGPG	HVRIKIRMDI	DVVTRTNKIR	DRFWDPGPAA	DPLTDLRYVW
501	511	521	531	541	551	561	571	581	591
GGFVYLQDLV	ERAAVRVLSG	ANPRAGLYLQ	QMPYPCYVDD	VFLRVLSRSL	PLFLTLAWIY	SVTLTVKAVV	REKETRLRDT	MRAMGLSRAV	LWLGWFLSCL
601	611	621	631	641	651	661	671	681	691
GPFLLSAALL	VLVLKLGDIL	PYSHPGVVFL	FLAAFAVATV	TQSFLLSAFF	SRANLAAACG	GLAYFSLYLP	YVLCVAWRDR	LPAGGRVAAS	LLSPVAFGFG
701	711	721	731	741	751	761	771	781	791
CESLALLEEQ	GEGAQWHNVG	TRPTADVFSL	AQVSGLLLLD	AALYGLATWY	LEAVCPGQYG	IPEPWNFPFR	RSYWCGPRPP	KSPAPCPTPL	DPKVLVEEAP
801	811	821	831	841	851	861	871	881	891
PGLSPGVSVR	SLEKRFPGSP	QPALRGLSLD	FYQGHITAFL	GHNGAGKTTT	LSILSGLFPP	SGGSAFILGH	DVRSSMAAIR	PHLGVCPQYN	VLFDMLTVDE
901	911	921	931	941	951	961	971	981	991
HVWFYGRLKG	LSAAVVGPEQ	DRLLQDVGLV	SKQSVQTRHL	SGGMQRKLSV	AIAFVGGSQV	VILDEPTAGV	DPASRRGIWE	LLLKYREGRT	LILSTHHLDE
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
AELLGDRVAV	VAGGRLCCCG	SPLFLRRHLG	SGYYLTLVKA	RLPLTTNEKA	DTDMEGSVDT	RQEKKNGSQG	SRVGTPQLLA	LVQHWVPGAR	LVEELPHELV
1101	1111	1121	1131	1141	1151	1161	1171	1181	1191
LVLPYTGAHD	GSFATLFREL	DTRLAELRLT	GYGISDTSLE	EIFLKVVEEC	AADTDMEDGS	CGQHLCTGIA	GLDVTLRLKM	PPQETALENG	EPAGSAPETD
1201	1211	1221	1231	1241	1251	1261	1271	1281	1291
QGSGPDAVGR	VQGWALTRQQ	LQALLLKRFL	LARRSRRGLF	AQIVLPALFV	GLALVFSLIV	PPFGHYPALR	LSPTMYGAQV	SFFSEDAPGD	PGRARLLEAL
1301	1311	1321	1331	1341	1351	1361	1371	1381	1391
LQEAGLEEPP	VQHSSHRFSA	PEVPAEVAKV	LASGNWTPES	PSPACQCSRP	GARRLLPDCP	AAAGGPPPPQ	AVTGSGEVVQ	NLTGRNLSDF	LVKTYPRLVR
1401	1411	1421	1431	1441	1451	1461	1471	1481	1491
QGLKTKKWVN	EVRYGGFSLG	GRDPGLPSGQ	ELGRSVEELW	ALLSPLPGGA	LDRVLKNLTA	WAHSLDAQDS	LKIWFNNKGW	HSMVAFVNRA	SNAILRAHLP
1501	1511	1521	1531	1541	1551	1561	1571	1581	1591
PGPARHAHSI	TTLNHPLNLT	KEQLSEGALM	ASSVDVLVSI	CVVFAMSFVP	ASFTLVLIEE	RVTRAKHLQL	MGGLSPTLYW	LGNFLWDMCN	YLVPACIVVL
1601	1611	1621	1631	1641	1651	1661	1671	1681	1691
IFLAFQQRAY	VAPANLPALL	LLLLLYGWSI	TPLMYPASFF	FSVPSTAYVV	LTCINLFIGI	NGSMATFVLE	LFSDQKLQEV	SRILKQVFLI	FPHFCLGRGL
1701	1711	1721	1731	1741	1751	1761	1771	1781	1791
IDMVRNQAMA	DAFERLGDRQ	FQSPLRWEVV	GKNLLAMVIQ	GPLFLLFTLL	LQHRSQLLPQ	PRVRSLPLLG	EEDEDVARER	ERVVQGATQG	DVLVLRNLTK
1801	1811	1821	1831	1841	1851	1861	1871	1881	1891
VYRGQRMPAV	DRLCLGIPPG	ECFGLLGVNG	AGKTSTFRMV	TGDTLASRGE	AVLAGHSVAR	EPSAAHLSMG	YCPQSDAIFE	LLTGREHLEL	LARLRGVPEA
1901	1911	1921	1931	1941	1951	1961	1971	1981	1991
QVAQTAGSGL	ARLGLSWYAD	RPAGTYSGGN	KRKLATALAL	VGDPAVVFLD	EPTTGMDPSA	RRFLWNSLLA	VVREGRSVML	TSHSMEECEA	LCSRLAIMVN
2001	2011	2021	2031	2041	2051	2061	2071	2081	2091
GRFRCLGSPQ	HLKGRFAAGH	TLTLRVPAAR	SQPAAAFVAA	EFPGAELREA	HGGRLRFQLP	PGGRCALARV	FGELAVHGAE	HGVEDFSVSQ	TMLEEVFLYF
2101	2111	2121	2131	2141
SKDQGKDEDT	EEQKEAGVGV	DPAPGLQHPK	RVSQFLDDPS	TAETVL

Reference

ID	Publication
2	Shah P, Wang X, Yang W, Eshghi ST, Sun S, Hoti N, Chen L, Yang S, Pasay J, Rubin A: Integrated Proteomic and Glycoproteomic Analyses of Prostate Cancer Cells Reveal Glycoprotein Alteration in Protein Abundance and Glycosylation. Molecular & Cellular Proteomics 2015, 14:2753-2763.
12	Weng Y, Sui Z, Jiang H, Shan Y, Chen L, Zhang S, Zhang L, Zhang Y: Releasing N-glycan from Peptide N-terminus by N-terminal Succinylation Assisted Enzymatic Deglycosylation. Scientific Reports 2015, 5.
16	Deeb SJ, Cox J, Schmidt-Supprian M, Mann M: N-linked Glycosylation Enrichment for In-depth Cell Surface Proteomics of Diffuse Large B-cell Lymphoma Subtypes. Molecular & Cellular Proteomics 2014, 13:240-251.
33	Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.