Contains      

UniProtKB-Q8N3J6

Protein Cell adhesion molecule 2
Gene CADM2
Status Reviewed
Source Colorectal tumor; Liver; OVCAR-3 cell line (Ovarian cancer); Ovarian tumor; Pancreatic islets; Prostate tumor; Urine
Years 2007-2015

Glycosites

Site Identified Peptides Year(Publication ID)
31 GSQGQFPLTQnVTVVEGGTAIL 2012(48);
31 GSQGQFPLTQnVTVVEGGTAILT 2012(48);
31 GSQGQFPLTQnVTVVEGGTAILTCR 2015(unpublished);2015(unpublished);
51 VDQNDnTSLQWSNPAQQTLYFDDKK 2007(48); 2012(45); 2013(unpublished);2015(unpublished);2015;2007;2007;
211 VDHESLnATPQVAMQVLEIHYTPSVK 2014(33);
287 LNILFLnK 2012(48);
287 ELNILFLnK 2007(48); 2012(45); 2013(22); 2014(33); 2014(1); 2015(unpublished);2015(unpublished);2015;2015;2015;2007;2007;
287 ELNILFLnKTDNGTYR 2012(48); 2015(unpublished);2015(unpublished);
291 TDnGTYR 2012(48); 2014(22); 2014(33); 2015(unpublished);2015(unpublished);
291 ELNILFLNKTDnGTYR 2012(48); 2015(unpublished);2015(unpublished);

Sequence

1112131415161718191
MIWKRSAVLRFYSVCGLLLQGSQGQFPLTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSISVSDVSLSDEG
101111121131141151161171181191
QYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVA
201211221231241251261271281291
VICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEATN
301311321331341351361371381391
TIGQSSAEYVLIVHDVPNTLLPTTIIPSLTTATVTTTVAITTSPTTSATTSSIRDPNALAGQNGPDHALIGGIVAVVVFVTLCSIFLLGRYLARHKGTYL
401411421431
TNEAKGAEDAPDADTAIINAEGSQVNAEEKKEYFI

Reference

ID Publication
1Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
22Nicastri A, Gaspari M, Sacco R, Elia L, Gabriele C, Romano R, Rizzuto A, Cuda G: N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue. Journal of Proteome Research 2014, 13:4932-4941.
33Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.
45Zhou H, Froehlich JW, Briscoe AC, Lee RS: The GlycoFilter: A Simple and Comprehensive Sample Preparation Platform for Proteomics, N-Glycomics and Glycosylation Site Assignment. Molecular & Cellular Proteomics 2013, 12:2981-2991.
48Danzer C, Eckhardt K, Schmidt A, Fankhauser N, Ribrioux S, Wollscheid B, Mueller L, Schiess R, Zuellig R, Lehmann R, et al: Comprehensive Description of the N-Glycoproteome of Mouse Pancreatic beta-Cells and Human Islets. Journal of Proteome Research 2012, 11:1598-1608.