| Protein | Immunoglobulin superfamily member 1 |
| Gene | IGSF1 |
| Status | Reviewed |
| Source | Bladder stromal cell line; Breast Cancer cell lines; HEK293 cell line (embryonic kidney); HepG2 cell line (Liver); HuH-7 cell line (Liver); Liver; Liver tumor (HCC); OVCAR-3 cell line (Ovarian cancer); Pancreatic islets; Prostate stromal cell line |
| Years | 2009-2015 |
| Site | Identified Peptides | Year(Publication ID) |
|---|---|---|
| 53 | nLTLWCR | 2014(15); |
| 607 | nLTLWCR | 2014(15); |
| 747 | MEDKDEGnYSCR | 2012(48); |
| 747 | EDKDEGnYSCRTH | 2013(37); |
| 747 | MEDKDEGnYSCRTHTEK | 2013(38); 2013(38); |
| 939 | nYSCIYYETTMSNR | 2015(1); |
| 939 | SVSGNSADFIIHTVGAEDSGnYSCIYYETTMSNR | 2014(32); |
| 1027 | nISGTSMGR | 2015(1); |
| 1223 | GIGnYSCSYR | 2009(65); 2009(65); 2012(48); 2013(38); 2013(38); 2014(15); 2014(33); |
| 1223 | EGKGIGnYSCSYR | 2013(37); |
| 1 | 11 | 21 | 31 | 41 | 51 | 61 | 71 | 81 | 91 |
| MTLDRPGEGA | TMLKTFTVLL | FCIRMSLGMT | SIVMDPQPEL | WIESNYPQAP | WENITLWCRS | PSRISSKFLL | LKDKTQMTWI | RPSHKTFQVS | FLIGALTESN |
| 101 | 111 | 121 | 131 | 141 | 151 | 161 | 171 | 181 | 191 |
| AGLYRCCYWK | ETGWSKPSKV | LELEAPGQLP | KPIFWIQAET | PALPGCNVNI | LCHGWLQDLV | FMLFKEGYAE | PVDYQVPTGT | MAIFSIDNLT | PEDEGVYICR |
| 201 | 211 | 221 | 231 | 241 | 251 | 261 | 271 | 281 | 291 |
| THIQMLPTLW | SEPSNPLKLV | VAGLYPKPTL | TAHPGPIMAP | GESLNLRCQG | PIYGMTFALM | RVEDLEKSFY | HKKTIKNEAN | FFFQSLKIQD | TGHYLCFYYD |
| 301 | 311 | 321 | 331 | 341 | 351 | 361 | 371 | 381 | 391 |
| ASYRGSLLSD | VLKIWVTDTF | PKTWLLARPS | AVVQMGQNVS | LRCRGPVDGV | GLALYKKGED | KPLQFLDATS | IDDNTSFFLN | NVTYSDTGIY | SCHYLLTWKT |
| 401 | 411 | 421 | 431 | 441 | 451 | 461 | 471 | 481 | 491 |
| SIRMPSHNTV | ELMVVDKPPK | PSLSAWPSTV | FKLGKAITLQ | CRVSHPVLEF | SLEWEERETF | QKFSVNGDFI | ISNVDGKGTG | TYSCSYRVET | HPNIWSHRSE |
| 501 | 511 | 521 | 531 | 541 | 551 | 561 | 571 | 581 | 591 |
| PLKLMGPAGY | LTWNYVLNEA | IRLSLIMQLV | ALLLVVLWIR | WKCRRLRIRE | AWLLGTAQGV | TMLFIVTALL | CCGLCNGVLI | EETEIVMPTP | KPELWAETNF |
| 601 | 611 | 621 | 631 | 641 | 651 | 661 | 671 | 681 | 691 |
| PLAPWKNLTL | WCRSPSGSTK | EFVLLKDGTG | WIATRPASEQ | VRAAFPLGAL | TQSHTGSYHC | HSWEEMAVSE | PSEALELVGT | DILPKPVISA | SPTIRGQELQ |
| 701 | 711 | 721 | 731 | 741 | 751 | 761 | 771 | 781 | 791 |
| LRCKGWLAGM | GFALYKEGEQ | EPVQQLGAVG | REAFFTIQRM | EDKDEGNYSC | RTHTEKRPFK | WSEPSEPLEL | VIKEMYPKPF | FKTWASPVVT | PGARVTFNCS |
| 801 | 811 | 821 | 831 | 841 | 851 | 861 | 871 | 881 | 891 |
| TPHQHMSFIL | YKDGSEIASS | DRSWASPGAS | AAHFLIISVG | IGDGGNYSCR | YYDFSIWSEP | SDPVELVVTE | FYPKPTLLAQ | PGPVVFPGKS | VILRCQGTFQ |
| 901 | 911 | 921 | 931 | 941 | 951 | 961 | 971 | 981 | 991 |
| GMRFALLQEG | AHVPLQFRSV | SGNSADFLLH | TVGAEDSGNY | SCIYYETTMS | NRGSYLSMPL | MIWVTDTFPK | PWLFAEPSSV | VPMGQNVTLW | CRGPVHGVGY |
| 1001 | 1011 | 1021 | 1031 | 1041 | 1051 | 1061 | 1071 | 1081 | 1091 |
| ILHKEGEATS | MQLWGSTSND | GAFPITNISG | TSMGRYSCCY | HPDWTSSIKI | QPSNTLELLV | TGLLPKPSLL | AQPGPMVAPG | ENMTLQCQGE | LPDSTFVLLK |
| 1101 | 1111 | 1121 | 1131 | 1141 | 1151 | 1161 | 1171 | 1181 | 1191 |
| EGAQEPLEQQ | RPSGYRADFW | MPAVRGEDSG | IYSCVYYLDS | TPFAASNHSD | SLEIWVTDKP | PKPSLSAWPS | TMFKLGKDIT | LQCRGPLPGV | EFVLEHDGEE |
| 1201 | 1211 | 1221 | 1231 | 1241 | 1251 | 1261 | 1271 | 1281 | 1291 |
| APQQFSEDGD | FVINNVEGKG | IGNYSCSYRL | QAYPDIWSEP | SDPLELVGAA | GPVAQECTVG | NIVRSSLIVV | VVVALGVVLA | IEWKKWPRLR | TRGSETDGRD |
| 1301 | 1311 | 1321 | 1331 | ||||||
| QTIALEECNQ | EGEPGTPANS | PSSTSQRISV | ELPVPI |
| ID | Publication |
|---|---|
| 1 | Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication. |
| 15 | Chen R, Seebun D, Ye M, Zou H, Figeys D: Site-specific characterization of cell membrane N-glycosylation with integrated hydrophilic interaction chromatography solid phase extraction and LC-MS/MS. Journal of Proteomics 2014, 103:194-203. |
| 32 | Zhang Z, Sun Z, Zhu J, Liu J, Huang G, Ye M, Zou H: High-Throughput Determination of the Site-Specific N-Sialoglycan Occupancy Rates by Differential Oxidation of Glycoproteins Followed with Quantitative Glycoproteomics Analysis. Analytical Chemistry 2014, 86:9830-9837. |
| 33 | Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721. |
| 37 | Boersema PJ, Geiger T, Wisniewski JR, Mann M: Quantification of the N-glycosylated Secretome by Super-SILAC During Breast Cancer Progression and in Human Blood Samples. Molecular & Cellular Proteomics 2013, 12:158-171. |
| 38 | Kaji H, Ocho M, Togayachi A, Kuno A, Sogabe M, Ohkura T, Nozaki H, Angata T, Chiba Y, Ozaki H, et al: Glycoproteomic Discovery of Serological Biomarker Candidates for HCV/HBV Infection-Associated Liver Fibrosis and Hepatocellular Carcinoma. Journal of Proteome Research 2013, 12:2630-2640. |
| 48 | Danzer C, Eckhardt K, Schmidt A, Fankhauser N, Ribrioux S, Wollscheid B, Mueller L, Schiess R, Zuellig R, Lehmann R, et al: Comprehensive Description of the N-Glycoproteome of Mouse Pancreatic beta-Cells and Human Islets. Journal of Proteome Research 2012, 11:1598-1608. |
| 65 | Goo YA, Lilu AY, Ryu S, Shaffer SA, Malmstrom L, Page L, Nguyen LT, Doneanu CE, Goodlett DR: Identification of Secreted Glycoproteins of Human Prostate and Bladder Stromal Cells by Comparative Quantitative Proteomics. Prostate 2009, 69:49-61. |