| Protein | Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 |
| Gene | POMGNT2 |
| Status | Reviewed |
| Source | Breast cancer xenografts; DLBCL cell lines (Diffuse large B-cell lymphoma); HEK293 cell line (embryonic kidney); IGROV-1/CP cell line (Ovarian cancer)IGROV-1/CP; LNCap/PC3 cell lines (Prostate cancer); Liver; OVCAR-3 cell line (Ovarian cancer); Ovarian tumor; Prostate tumor; Urine |
| Years | 2007-2015 |
| Site | Identified Peptides | Year(Publication ID) |
|---|---|---|
| 99 | nTSVMLPNLGSR | 2015(1); |
| 276 | LnVSHTGVPLGE | 2014(33); |
| 276 | LnVSHTGVPLGEE | 2014(33); |
| 276 | MTEKLnVSHTGVPLGEEY | 2014(33); |
| 276 | InVSHTGVPIGEEYIIVFSR | 2014(16); |
| 276 | LnVSHTGVPLGEEYILVFSR | 2007(75); 2007(15); 2014(33); 2014(1); 2015(2); 2015(unpublished);2015(unpublished);2015;2007;2007; |
| 276 | FMTEKLnVSHTGVPLGEEYILVFSR | 2015(2); |
| 337 | LVSnASMLVSMHGAQLVTTLFLPR | 2015(unpublished);2015(1); |
| 543 | ILALQnHTFTE | 2014(33); |
| 543 | ALQnHTFTENIKPF | 2014(33); |
| 1 | 11 | 21 | 31 | 41 | 51 | 61 | 71 | 81 | 91 |
| MHLSAVFNAL | LVSVLAAVLW | KHVRLREHAA | TLEEELALSR | QATEPAPALR | IDYPKALQIL | MEGGTHMVCT | GRTHTDRICR | FKWLCYSNEA | EEFIFFHGNT |
| 101 | 111 | 121 | 131 | 141 | 151 | 161 | 171 | 181 | 191 |
| SVMLPNLGSR | RFQPALLDLS | TVEDHNTQYF | NFVELPAAAL | RFMPKPVFVP | DVALIANRFN | PDNLMHVFHD | DLLPLFYTLR | QFPGLAHEAR | LFFMEGWGEG |
| 201 | 211 | 221 | 231 | 241 | 251 | 261 | 271 | 281 | 291 |
| AHFDLYKLLS | PKQPLLRAQL | KTLGRLLCFS | HAFVGLSKIT | TWYQYGFVQP | QGPKANILVS | GNEIRQFARF | MTEKLNVSHT | GVPLGEEYIL | VFSRTQNRLI |
| 301 | 311 | 321 | 331 | 341 | 351 | 361 | 371 | 381 | 391 |
| LNEAELLLAL | AQEFQMKTVT | VSLEDHTFAD | VVRLVSNASM | LVSMHGAQLV | TTLFLPRGAT | VVELFPYAVN | PDHYTPYKTL | AMLPGMDLQY | VAWRNMMPEN |
| 401 | 411 | 421 | 431 | 441 | 451 | 461 | 471 | 481 | 491 |
| TVTHPERPWD | QGGITHLDRA | EQARILQSRE | VPRHLCCRNP | EWLFRIYQDT | KVDIPSLIQT | IRRVVKGRPG | PRKQKWTVGL | YPGKVREARC | QASVHGASEA |
| 501 | 511 | 521 | 531 | 541 | 551 | 561 | 571 | ||
| RLTVSWQIPW | NLKYLKVREV | KYEVWLQEQG | ENTYVPYILA | LQNHTFTENI | KPFTTYLVWV | RCIFNKILLG | PFADVLVCNT |
| ID | Publication |
|---|---|
| 1 | Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication. |
| 2 | Shah P, Wang X, Yang W, Eshghi ST, Sun S, Hoti N, Chen L, Yang S, Pasay J, Rubin A: Integrated Proteomic and Glycoproteomic Analyses of Prostate Cancer Cells Reveal Glycoprotein Alteration in Protein Abundance and Glycosylation. Molecular & Cellular Proteomics 2015, 14:2753-2763. |
| 15 | Chen R, Seebun D, Ye M, Zou H, Figeys D: Site-specific characterization of cell membrane N-glycosylation with integrated hydrophilic interaction chromatography solid phase extraction and LC-MS/MS. Journal of Proteomics 2014, 103:194-203. |
| 16 | Deeb SJ, Cox J, Schmidt-Supprian M, Mann M: N-linked Glycosylation Enrichment for In-depth Cell Surface Proteomics of Diffuse Large B-cell Lymphoma Subtypes. Molecular & Cellular Proteomics 2014, 13:240-251. |
| 33 | Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721. |
| 75 | Sun B, Ranish JA, Utleg AG, White JT, Yan X, Lin B, Hood L: Shotgun glycopeptide capture approach coupled with mass Spectrometry for comprehensive glycoproteomics. Molecular & Cellular Proteomics 2007, 6:141-149. |