| Protein | Hemicentin-2 |
| Gene | HMCN2 |
| Status | Reviewed |
| Source | Colorectal tumor; Serum; Urine |
| Years | 2013-2015 |
| Site | Identified Peptides | Year(Publication ID) |
|---|---|---|
| 547 | VLGEAPYnLTWVR | 2015(unpublished);2015(unpublished); |
| 1024 | GPHYnVSK | 2015(10); |
| 2435 | RnFSVEVLVPPSIENEDLEEVIK | 2015(unpublished);2015(unpublished); |
| 2468 | VLDGQTAHLMCnVTGHPQPK | 2013(45); |
| 2507 | GDAHHISPDGVLLQVLQAnLSSAGHYSCIAANAVGEK | 2013(45); |
| 4270 | HQLQnGSLTIHR | 2015(unpublished);2015(unpublished);2015(unpublished); |
| 4810 | NGQnVTTVSHR | 2014(22); |
| 5000 | LTAFSEVGVPAnR | 2015(unpublished);2015(unpublished);2015(unpublished); |
| 1 | 11 | 21 | 31 | 41 | 51 | 61 | 71 | 81 | 91 |
| MMPGAPLLRL | LTAVSAAVAV | AVAGAPGTVM | PPTTGDATLA | FVFDVTGSMW | DELMQVIDGA | SRILERSLSR | RSQAIANYAL | VPFHDPDIGP | VTLTADPTVF |
| 101 | 111 | 121 | 131 | 141 | 151 | 161 | 171 | 181 | 191 |
| QRELRELYVQ | GGGDCPEMSV | GAIKAAVEVA | NPGSFIYVFS | DARAKDYHKK | EELLRLLQLK | QSQVVFVLTG | DCGDRTHPGY | LAYEEIAATS | SGQVFHLDKQ |
| 201 | 211 | 221 | 231 | 241 | 251 | 261 | 271 | 281 | 291 |
| QVTEVLKWVE | SAIQASKVHL | LSTDHEEEGE | HTWRLPFDPS | LKEVTISLSG | PGPEIEVQDP | LGRILQEDEG | LNVLLNIPDS | AKVVAFKPEH | PGLWSIKVYS |
| 301 | 311 | 321 | 331 | 341 | 351 | 361 | 371 | 381 | 391 |
| SGRHSVRITG | VSNIDFRAGF | STQPLLDLNH | TLEWPLQGVP | ISLVINSTGL | KAPGRLDSVE | LAQSSGKPLL | TLPTKPLSNG | STHQLWGGPP | FHTPKERFYL |
| 401 | 411 | 421 | 431 | 441 | 451 | 461 | 471 | 481 | 491 |
| KVKGKDHEGN | PLLRVSGVSY | SGVAPGAPLV | SMAPRIHGYL | HQPLLVSCSV | HSALPFRLQL | RRGEARLGEE | RHFQESGNSS | WEILRASKAE | EGTYECTAVS |
| 501 | 511 | 521 | 531 | 541 | 551 | 561 | 571 | 581 | 591 |
| RAGTGRAKAQ | IVVTDPPPQL | VPAPNVTVSP | GETAVLSCRV | LGEAPYNLTW | VRDWRVLPAS | TGRVAQLADL | SLEISGIIPT | DGGRYQCVAS | NANGVTRASV |
| 601 | 611 | 621 | 631 | 641 | 651 | 661 | 671 | 681 | 691 |
| WLLVREAPQV | SIHTSSQHFS | QGVEVKVSCS | ASGYPTPHIS | WSRESQALQE | DSRIHVDAQG | TLIIQGVAPE | DAGNYSCQAT | NEVGTDQETV | TLYYTDPPSV |
| 701 | 711 | 721 | 731 | 741 | 751 | 761 | 771 | 781 | 791 |
| SAVNAVVLVA | VGEEAVLVCE | ASGVPPPRVI | WYRGGLEMIL | APEGSSSGKL | RIPAAQERDA | GTYTCRAVNE | LGDASAEIQL | AVGHAPQLTE | LPRDVTVELG |
| 801 | 811 | 821 | 831 | 841 | 851 | 861 | 871 | 881 | 891 |
| RSALLACRAT | GRPPPTVTWR | RGDGQPLGLR | LGAGRGSRSR | QPDSGVLFFE | SVAPEDQAPY | VCEARNVFGK | VQAEARLIVT | GHAPPQIASS | APTVRVLEGQ |
| 901 | 911 | 921 | 931 | 941 | 951 | 961 | 971 | 981 | 991 |
| PVSLPCIVLA | GRPLPERHWL | KDGRPLPPGS | RHSIRADGSL | HLDRALQEHA | GRYSCVATNT | AGSQHRDVEL | VVQVPPRIHP | TATHHITNEG | VPASLPCVAS |
| 1001 | 1011 | 1021 | 1031 | 1041 | 1051 | 1061 | 1071 | 1081 | 1091 |
| GVPAPTITWT | KETNALTSRG | PHYNVSKEGT | LLIAQPSAQD | AGAYVCTATN | TVGFSSQEMR | LSVNRLALSK | YVWEEYGLLP | SGSLRLAQVQ | VGDSGHYECT |
| 1101 | 1111 | 1121 | 1131 | 1141 | 1151 | 1161 | 1171 | 1181 | 1191 |
| ASNPAGSASH | RYVLGVQVPP | QVQPGPRVLK | VLVGEALDLN | CVAEGNPEPQ | LSWSKDGVVL | QGRGPQGSVH | FAAIRTSDAG | RYRCEASNSA | GVDAWEVELR |
| 1201 | 1211 | 1221 | 1231 | 1241 | 1251 | 1261 | 1271 | 1281 | 1291 |
| VLEPPHWGAD | ETSGLLERVA | GENASLPCPA | RGTPKPQVTW | RKGPSSEPLH | GQPGVAVLEE | GSLFLASVSP | ADSGDYECQA | TNEVGSTSRR | AKLVVYVPPS |
| 1301 | 1311 | 1321 | 1331 | 1341 | 1351 | 1361 | 1371 | 1381 | 1391 |
| IREDGRKANV | SGMAGQSLTL | ECDANGFPVP | EIVWLKDAQL | VGVPLGWAGY | GWDLGWGQVG | GHRLLDEGQS | LHFPRIQEGD | SGLYSCRAEN | QAGTAQRDFH |
| 1401 | 1411 | 1421 | 1431 | 1441 | 1451 | 1461 | 1471 | 1481 | 1491 |
| LLVLTPPSVL | GAGAAQEVLG | LAGADVELQC | WTSGVPTPQV | EWTKDRQPVL | PGGPHLQVQE | DGQVLRITGS | HVGDEGRYQC | VAFSPAGQQA | RDFQLRVHAP |
| 1501 | 1511 | 1521 | 1531 | 1541 | 1551 | 1561 | 1571 | 1581 | 1591 |
| PTIWGSNETG | EVAVMEDHLV | QLLCEARGVP | TPNITWFKDG | ALLPTSTKVV | YTRGGRQLQL | GRAQSSDAGV | YTCKASNAVG | AAEKATRLDV | YVPPTIEGAG |
| 1601 | 1611 | 1621 | 1631 | 1641 | 1651 | 1661 | 1671 | 1681 | 1691 |
| GRPYVVKAVA | GRPVALECVA | RGHPSPTLSW | HHEGLPVAES | NESRLETDGS | VLRLESPGEA | SSGLYSCVAS | SPAGEAVLQY | SVEVQVPPQL | LVAEGLGQVT |
| 1701 | 1711 | 1721 | 1731 | 1741 | 1751 | 1761 | 1771 | 1781 | 1791 |
| TIVGQPLELP | CQASGSPVPT | IQWLQNGRPA | EELAGVQVAS | QGTTLHIDHV | ELDHSGLFAC | QATNEAGTAG | AEVEVSVHGE | WAPGVLEVPI | GQYHWGXEHH |
| 1801 | 1811 | 1821 | 1831 | 1841 | 1851 | 1861 | 1871 | 1881 | 1891 |
| SSFPAACDPP | VHRGWGAHPK | PPLVEGWCSP | GSLWGEPTGI | PVAYSLPPPL | QIEKVDLRDE | GIYTCAATNL | AGESKREVAL | KVLVPPNIEP | GPVNKAVLEN |
| 1901 | 1911 | 1921 | 1931 | 1941 | 1951 | 1961 | 1971 | 1981 | 1991 |
| ASVTLECLAS | GVPPPDVSWF | KGHQPVSSWM | GVTVSVDGRV | LRIEQAQLSD | AGSYRCVASN | VAGSTELRYG | LRVNVPPRIT | LPPSLPGPVL | VNTPVRLTCN |
| 2001 | 2011 | 2021 | 2031 | 2041 | 2051 | 2061 | 2071 | 2081 | 2091 |
| ATGAPSPTLM | WLKDGNPVSP | AGTPGLQVFP | GGRVLTLASA | RASDSGRYSC | VAVSAVGEDR | QDVVLQVHMP | PSILGEELNV | SVVANESVAL | ECQSHAMPPP |
| 2101 | 2111 | 2121 | 2131 | 2141 | 2151 | 2161 | 2171 | 2181 | 2191 |
| VLSWWKDGRP | LEPRPGVHLS | ADKALLQVDR | ADVWDAGHYT | CEALNQAGHS | EKHYNLNVWV | APVFPLRESH | TLTVREGHPT | SLSCECRGVP | FPKISWRKDG |
| 2201 | 2211 | 2221 | 2231 | 2241 | 2251 | 2261 | 2271 | 2281 | 2291 |
| QPLPGEGAGL | QHVSAVGRLL | YLGQAQLAQE | GTYTCECSNV | VGNSSQDLQL | EVHVPPQIAG | PREPPTQVSV | VQDGVATLEC | NATGKPPPTV | TWERDGQPVG |
| 2301 | 2311 | 2321 | 2331 | 2341 | 2351 | 2361 | 2371 | 2381 | 2391 |
| AELGLQLQNQ | GQSLHVERAQ | AAHTGRYSCV | AENLAGRAER | KFELSVLVPP | ELIGDLDPLT | NITAALHSPL | TLLCEAMGIP | PPAIRWFRGE | EPVSPGEDTY |
| 2401 | 2411 | 2421 | 2431 | 2441 | 2451 | 2461 | 2471 | 2481 | 2491 |
| LLAGGWMLKM | TQTQEQDSGL | YSCLASNEAG | EARRNFSVEV | LVPPSIENED | LEEVIKVLDG | QTAHLMCNVT | GHPQPKLTWF | KDGRPLARGD | AHHISPDGVL |
| 2501 | 2511 | 2521 | 2531 | 2541 | 2551 | 2561 | 2571 | 2581 | 2591 |
| LQVLQANLSS | AGHYSCIAAN | AVGEKTKHFQ | LSVLLAPTIL | GGAEDSADEE | VTVTVNNPIS | LICEALAFPS | PNITWMKDGA | PFEASRNIQL | LPGTHGLQIL |
| 2601 | 2611 | 2621 | 2631 | 2641 | 2651 | 2661 | 2671 | 2681 | 2691 |
| NAQKEDAGQY | TCVVTNELGE | AVKNYHVEVL | IPPSISKDDP | LGEVGVKEVK | TKVNSTLTLE | CESWAVPPPT | IRWYKDGQPV | TPSSRLQVLG | EGRLLQIQPT |
| 2701 | 2711 | 2721 | 2731 | 2741 | 2751 | 2761 | 2771 | 2781 | 2791 |
| QVSDSGRYLC | VATNVAGEDD | QDFNVLIQVP | PMFQKVGDFS | AAFEILSREE | EARGGVTEYR | EIVENNPAYL | YCDTNAIPPP | DLTWYREDQP | LSAGDEVSVL |
| 2801 | 2811 | 2821 | 2831 | 2841 | 2851 | 2861 | 2871 | 2881 | 2891 |
| QGGRVLQIPL | VRAENAGRYS | CKASNEVGED | WLHYELLVLT | PPVILGDTEE | LVEEVTVNAS | STVSLQCPAL | GNPVPTISWL | QNGLPFSPSP | RLQVLEDGQV |
| 2901 | 2911 | 2921 | 2931 | 2941 | 2951 | 2961 | 2971 | 2981 | 2991 |
| LQVSTAEVAD | AASYMCVAEN | QAGSAEKLFT | LRVQVPPRIA | GLDLEQVTAI | LNSSVSLPCD | VHAHPNPEVT | WYKDSQALSL | GEEVFLLPGT | HTLQLGRARL |
| 3001 | 3011 | 3021 | 3031 | 3041 | 3051 | 3061 | 3071 | 3081 | 3091 |
| SDSGMYTCEA | LNAAGRDQKL | VQLSVLVPPA | FRQAPRGPQD | AVLVRVGDKA | VLSCETDALP | EPTVTWYKDG | QPLVLAQRTQ | ALRGGQRLEI | QEAQVSDKGL |
| 3101 | 3111 | 3121 | 3131 | 3141 | 3151 | 3161 | 3171 | 3181 | 3191 |
| YSCKVSNVAG | EAVRTFTLTV | QVPPTFENPK | TETVSQVAGS | PLVLTCDVSG | VPAPTVTWLK | DRMPVESSAV | HGVVSRGGRL | QLSRLQPAQA | GTYTCVAENT |
| 3201 | 3211 | 3221 | 3231 | 3241 | 3251 | 3261 | 3271 | 3281 | 3291 |
| QAEARKDFVV | AVLVAPRIRS | SGVAREHHVL | EGQEVRLDCE | ADGQPPPDVA | WLKDGSPLGQ | DMGPHLRFYL | DGGSLVLKGL | RASDAGAYTC | VAHNPAGEDA |
| 3301 | 3311 | 3321 | 3331 | 3341 | 3351 | 3361 | 3371 | 3381 | 3391 |
| RLHTVNVLVP | PTIKQGADGS | GTLVSRPGEL | VTMVCPVRGS | PPIHVSWLKD | GLPLPLSQRT | LLHGSGHTLR | ISKVQLADAG | IFTCVAASPA | GVADRNFTLQ |
| 3401 | 3411 | 3421 | 3431 | 3441 | 3451 | 3461 | 3471 | 3481 | 3491 |
| VQVPPVLEPV | EFQNDVVVVR | GSLVELPCEA | RGVPLPLVSW | MKDGEPLLSQ | SLEQGPSLQL | EAVGAGDSGT | YSCVAVSEAG | EARRHFQLTV | MEPPHIEDSG |
| 3501 | 3511 | 3521 | 3531 | 3541 | 3551 | 3561 | 3571 | 3581 | 3591 |
| QPTELSLTPG | APMELLCDAQ | GTPQPNITWH | KDGQALTRLE | NNSRATRVLR | VRDAGLYTCL | AESPAGAIEK | SFRVRVQAPP | NIVGPRGPRF | VVGLAPGQLV |
| 3601 | 3611 | 3621 | 3631 | 3641 | 3651 | 3661 | 3671 | 3681 | 3691 |
| LECSVEAEPA | PKITWHRDGI | VLQEDAHTQF | PERGRFLQLQ | ALSTADSGDY | SCTARNAAGS | TSVAFRVEIH | TVPTIRSGPP | AVNVSVNQTA | LLPCQADGVP |
| 3701 | 3711 | 3721 | 3731 | 3741 | 3751 | 3761 | 3771 | 3781 | 3791 |
| APLVSWRKDR | VPLDPRSPRF | EILPEGSLRI | QPVLAQDAGH | YLCLASNSAG | SDRQGRDLRV | LEPPAIAPSP | SNLTLTAHTP | ALLPCEASGS | PKPLVVWWKD |
| 3801 | 3811 | 3821 | 3831 | 3841 | 3851 | 3861 | 3871 | 3881 | 3891 |
| GQKLDFRLQQ | GAYRLLPSNA | LLLTAPGPQD | SAQFECVVSN | EVGEAHRLYQ | VTVHVPPTIA | DDQTDFTVTM | MAPVVLTCHS | TGIPAPTVSW | SKAGAQLGAR |
| 3901 | 3911 | 3921 | 3931 | 3941 | 3951 | 3961 | 3971 | 3981 | 3991 |
| GSGYRVSPSG | ALEIGQALPI | HAGRYTCSAR | NSAGVAHKHV | FLTVQASPVV | KPLPSVVRAV | AEEEVLLPCE | ASGIPRPTIT | WQKEGLNVAT | GVSTQVLPGG |
| 4001 | 4011 | 4021 | 4031 | 4041 | 4051 | 4061 | 4071 | 4081 | 4091 |
| QLRIAHASPE | DAGNYLCIAK | NSAGSAMGKT | RLVVQVPPVI | ENGLPDLSTT | EGSHAFLPCK | ARGSPEPNIT | WDKDGQPVSG | AEGKFTIQPS | GELLVKNLEG |
| 4101 | 4111 | 4121 | 4131 | 4141 | 4151 | 4161 | 4171 | 4181 | 4191 |
| QDAGTYTCTA | ENAVGRARRR | VHLTILVLPV | FTTLPGDRSL | RLGDRLWLRC | AARGSPTPRI | GWTVNDRPVT | EGVSEQDGGS | TLQRAAVSRE | DSGTYVCWAE |
| 4201 | 4211 | 4221 | 4231 | 4241 | 4251 | 4261 | 4271 | 4281 | 4291 |
| NRVGRTQAVS | FVHVKEAPVL | QGEAFSYLVE | PVGGSIQLDC | VVRGDPVPDI | HWIKDGLPLR | GSHLRHQLQN | GSLTIHRTER | DDAGRYQCLA | ENEMGVAKKV |
| 4301 | 4311 | 4321 | 4331 | 4341 | 4351 | 4361 | 4371 | 4381 | 4391 |
| VILVLQSAPV | FQVEPQDMTV | RSGDDVALRC | QATGEPTPTI | EWLQAGQPLR | ASRRLRTLPD | GSLWLENVET | GDAGTYDCVA | HNLLGSATAR | AFLVVRGEPQ |
| 4401 | 4411 | 4421 | 4431 | 4441 | 4451 | 4461 | 4471 | 4481 | 4491 |
| GSWGSMTGVI | NGRKFGVATL | NTSVMQEAHS | GVSSIHSSIR | HVPANVGPLM | RVLVVTIAPI | YWALARESGE | ALNGHSLTGG | RFRQESHVEF | ATGELLTMTQ |
| 4501 | 4511 | 4521 | 4531 | 4541 | 4551 | 4561 | 4571 | 4581 | 4591 |
| VARGLDPDGL | LLLDVVVNGV | VPESLADADL | QVQDFEEHYV | QTGPGQLFVG | STQRFFQGGL | PSFLRCNHSI | QYNAARGPQP | QLVQHLRASA | ISSAFDPEAE |
| 4601 | 4611 | 4621 | 4631 | 4641 | 4651 | 4661 | 4671 | 4681 | 4691 |
| ALRFQLATAL | QAEENEVGCP | EGFELDSQGA | FCVDRDECSG | GPSPCSHACL | NAPGRFSCTC | PTGFALAWDD | RNCRDVDECA | WDAHLCREGQ | RCVNLLGSYR |
| 4701 | 4711 | 4721 | 4731 | 4741 | 4751 | 4761 | 4771 | 4781 | 4791 |
| CLPDCGPGFR | VADGAGCEDV | DECLEGLDDC | HYNQLCENTP | GGHRCSCPRG | YRMQGPSLPC | LDVNECLQLP | KACAYQCHNL | QGSYRCLCPP | GQTLLRDGKA |
| 4801 | 4811 | 4821 | 4831 | 4841 | 4851 | 4861 | 4871 | 4881 | 4891 |
| CTSLERNGQN | VTTVSHRGPL | LPWLRPWASI | PGTSYHAWVS | LRPGPMALSS | VGRAWCPPGF | IRQNGVCTDL | DECRVRNLCQ | HACRNTEGSY | QCLCPAGYRL |
| 4901 | 4911 | 4921 | 4931 | 4941 | 4951 | 4961 | 4971 | 4981 | 4991 |
| LPSGKNCQDI | NECEEESIEC | GPGQMCFNTR | GSYQCVDTPC | PATYRQGPSP | GTCFRRCSQD | CGTGGPSTLQ | YRLLPLPLGV | RAHHDVARLT | AFSEVGVPAN |
| 5001 | 5011 | 5021 | 5031 | 5041 | 5051 | 5061 | |||
| RTELSMLEPD | PRSPFALRPL | RAGLGAVYTR | RALTRAGLYR | LTVRAAAPRH | QSVFVLLIAV | SPYPY |
| ID | Publication |
|---|---|
| 10 | Tan ZJ, Yin HD, Nie S, Lin ZX, Zhu JH, Ruffin MT, Anderson MA, Simone DM, Lubman DM: Large-Scale Identification of Core-Fucosylated Glycopeptide Sites in Pancreatic Cancer Serum Using Mass Spectrometry. Journal of Proteome Research 2015, 14:1968-1978. |
| 22 | Nicastri A, Gaspari M, Sacco R, Elia L, Gabriele C, Romano R, Rizzuto A, Cuda G: N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue. Journal of Proteome Research 2014, 13:4932-4941. |
| 45 | Zhou H, Froehlich JW, Briscoe AC, Lee RS: The GlycoFilter: A Simple and Comprehensive Sample Preparation Platform for Proteomics, N-Glycomics and Glycosylation Site Assignment. Molecular & Cellular Proteomics 2013, 12:2981-2991. |