Detail


Protein	Protocadherin Fat 3
Gene	FAT3
Status	Reviewed
Source	DLBCL cell lines (Diffuse large B-cell lymphoma); Liver; OVCAR-3 cell line (Ovarian cancer); Prostate tumor; Serum
Years	2007-2015

Site	Identified Peptides	Year(Publication ID)
342	nLTLQAK	2015(1);
668	ITATDGENIADPMSInISVIHGK	2014(16);
1007	nITVR	2014(33);
1007	nLTVR	2014(33);
1007	QQFYnITVR	2014(16);
2468	QRMEPLYSLnVSVSDGLFTSTAQVHIR	2007(unpublished);2007(unpublished);

Sequence

1	11	21	31	41	51	61	71	81	91
MDIIMGHCVG	TRPPACCLIL	LLFKLLATVS	QGLPGTGPLG	FHFTHSIYNA	TVYENSAART	YVNSQSRMGI	TLIDLSWDIK	YRIVSGDEEG	FFKAEEVIIA
101	111	121	131	141	151	161	171	181	191
DFCFLRIRTK	GGNSAILNRE	IQDNYLLIVK	GSVRGEDLEA	WTKVNIQVLD	MNDLRPLFSP	TTYSVTIAES	TPLRTSVAQV	TATDADIGSN	GEFYYYFKNK
201	211	221	231	241	251	261	271	281	291
VDLFSVHPTS	GVISLSGRLN	YDEKNRYDLE	ILAVDRGMKL	YGNNGVSSTA	KLYVHIERIN	EHAPTIHVVT	HVPFSLEKEP	TYAVVTVDDL	DDGANGEIES
301	311	321	331	341	351	361	371	381	391
VSIVAGDPLD	QFFLAKEGKW	LNEYKIKERK	QIDWESFPYG	YNLTLQAKDK	GSPQKCSALK	AVYIGNPTRD	TVPIRFEKEV	YDVSISEFSP	PGVVVAIVKL
401	411	421	431	441	451	461	471	481	491
SPEPIDVEYK	LSPGEDAVYF	KINPRSGLIV	TARPLNTVKK	EVYKLEVTNK	EGDLKAQVTI	SIEDANDHTP	EFQQPLYDAY	VNESVPVGTS	VLTVSASDKD
501	511	521	531	541	551	561	571	581	591
KGENGYITYS	IASLNLLPFV	INQFTGVIST	TEELDFESSP	EIYRFIVRAS	DWGSPYRHES	EVNVTIRIGN	VNDNSPLFEK	VACQGVISYD	FPVGGHITAV
601	611	621	631	641	651	661	671	681	691
SAIDIDELEL	VKYKIISGNE	LGFFYLNPDS	GVLQLKKSLT	NSGIKNGNFA	LRITATDGEN	LADPMSINIS	VLHGKVSSKS	FSCRETRVAQ	KLAEKLLIKA
701	711	721	731	741	751	761	771	781	791
KANGKLNLED	GFLDFYSINR	QGPYFDKSFP	SDVAVKEDLP	VGANILKIKA	YDADSGFNGK	VLFTISDGNT	DSCFNIDMET	GQLKVLMPMD	REHTDLYLLN
801	811	821	831	841	851	861	871	881	891
ITIYDLGNPQ	KSSWRLLTIN	VEDANDNSPV	FIQDSYSVNI	LESSGIGTEI	IQVEARDKDL	GSNGEVTYSV	LTDTQQFAIN	SSTGIVYVAD	QLDRESKANY
901	911	921	931	941	951	961	971	981	991
SLKIEARDKA	ESGQQLFSVV	TLKVFLDDVN	DCSPAFIPSS	YSVKVLEDLP	VGTVIAWLET	HDPDLGLGGQ	VRYSLVNDYN	GRFEIDKASG	AIRLSKELDY
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
EKQQFYNLTV	RAKDKGRPVS	LSSVSFVEVE	VVDVNENLHT	PYFPDFAVVG	SVKENSRIGT	SVLQVTARDE	DSGRDGEIQY	SIRDGSGLGR	FSIDDESGVI
1101	1111	1121	1131	1141	1151	1161	1171	1181	1191
TAADILDRET	MGSYWLTVYA	TDRGVVPLYS	TIEVYIEVED	VNDNAPLTSE	PIYYPVVMEN	SPKDVSVIQI	QAEDPDSSSN	EKLTYRITSG	NPQNFFAINI
1201	1211	1221	1231	1241	1251	1261	1271	1281	1291
KTGLITTTSR	KLDREQQAEH	FLEVTVTDGG	PSPKQSTIWV	VVQVLDENDN	KPQFPEKVYQ	IKLPERDRKK	RGEPIYRAFA	FDRDEGPNAE	ISYSIVDGND
1301	1311	1321	1331	1341	1351	1361	1371	1381	1391
DGKFFIDPKT	GMVSSRKQFT	AGSYDILTIK	AVDNGRPQKS	STARLHIEWI	KKPPPSPIPL	TFDEPFYNFT	VMESDRVTEI	VGVVSVQPAN	TPLWFDIVGG
1401	1411	1421	1431	1441	1451	1461	1471	1481	1491
NFDSAFDAEK	GVGTIVIAKP	LDAEQRSIYN	MSVEVTDGTN	VAVTQVFIKV	LDNNDNGPEF	SQPNYDVTIS	EDVLPDTEIL	QIEATDRDEK	HKLSYTVHSS
1501	1511	1521	1531	1541	1551	1561	1571	1581	1591
IDSISMRKFR	IDPSTGVLYT	AERLDHEAQD	KHILNIMVRD	QEFPYRRNLA	RVIVNVEDAN	DHSPYFTNPL	YEASVFESAA	LGSAVLQVTA	LDKDKGENAE
1601	1611	1621	1631	1641	1651	1661	1671	1681	1691
LIYTIEAGNT	GNMFKIEPVL	GIITICKEPD	MTTMGQFVLS	IKVTDQGSPP	MSATAIVRIS	VTMSDNSHPK	FIHKDYQAEV	NENVDIGTSV	ILISAISQST
1701	1711	1721	1731	1741	1751	1761	1771	1781	1791
LIYEVKDGDI	NGIFTINPYS	GVITTQKALD	YERTSSYQLI	IQATNMAGMA	SNATVNIQIV	DENDNAPVFL	FSQYSGSLSE	AAPINSIVRS	LDNSPLVIRA
1801	1811	1821	1831	1841	1851	1861	1871	1881	1891
TDADSNRNAL	LVYQIVESTA	KKFFTVDSST	GAIRTIANLD	HETIAHFHFH	VHVRDSGSPQ	LTAESPVEVN	IEVTDVNDNP	PVFTQAVFET	ILLLPTYVGV
1901	1911	1921	1931	1941	1951	1961	1971	1981	1991
EVLKVSATDP	DSEVPPELTY	SLMEGSLDHF	LIDSNSGVLT	IKNNNLSKDH	YMLIVKVSDG	KFYSTSMVTI	MVKEAMDSGL	HFTQSFYSTS	ISENNTNITK
2001	2011	2021	2031	2041	2051	2061	2071	2081	2091
VAIVNAVGNR	LNEPLKYSIL	NPGNKFKIKS	TSGVIQTTGV	PFDREEQELY	ELVVEASREL	DHLRVARVVV	RVNIEDINDN	SPVFVGLPYY	AAVQVDAEPG
2101	2111	2121	2131	2141	2151	2161	2171	2181	2191
TLIYQVTAID	KDKGPNGEVT	YVLQDDYGHF	EINPNSGNVI	LKEAFNSDLS	NIEYGVTILA	KDGGKPSLST	SVELPITIVN	KAMPVFDKPF	YTASVNEDIR
2201	2211	2221	2231	2241	2251	2261	2271	2281	2291
MNTPILSINA	TSPEGQGIIY	IIIDGDPFKQ	FNIDFDTGVL	KVVSPLDYEV	TSAYKLTIRA	SDALTGARAE	VTVDLLVNDV	NDNPPIFDQP	TYNTTLSEAS
2301	2311	2321	2331	2341	2351	2361	2371	2381	2391
LIGTPVLQVV	SIDADSENNK	MVHYQIVQDT	YNSTDYFHID	SSSGLILTAR	MLDHELVQHC	TLKVRSIDSG	FPSLSSEVLV	HIYISDVNDN	PPVFNQLIYE
2401	2411	2421	2431	2441	2451	2461	2471	2481	2491
SYVSELAPRG	HFVTCVQASD	ADSSDFDRLE	YSILSGNDRT	SFLMDSKSGV	ITLSNHRKQR	MEPLYSLNVS	VSDGLFTSTA	QVHIRVLGAN	LYSPAFSQST
2501	2511	2521	2531	2541	2551	2561	2571	2581	2591
YVAEVRENVA	AGTKVIHVRA	TDGDPGTYGQ	ISYAIINDFA	KDRFLIDSNG	QVITTERLDR	ENPLEGDVSI	FVRALDGGGR	TTFCTVRVIV	VDENDNAPQF
2601	2611	2621	2631	2641	2651	2661	2671	2681	2691
MTVEYRASVR	ADVGRGHLVT	QVQAIDPDDG	ANSRITYSLY	SEASVSVADL	LEIDPDNGWM	VTKGNFNQLK	NTVLSFFVKA	VDGGIPVKHS	LIPVYIHVLP
2701	2711	2721	2731	2741	2751	2761	2771	2781	2791
PETFLPSFTQ	SQYSFTIAED	TAIGSTVDTL	RILPSQNVWF	STVNGERPEN	NKGGIFVIEQ	ETGTIKLDKR	LDRETSPAFH	FKVAATIPLD	KVDIVFTVDV
2801	2811	2821	2831	2841	2851	2861	2871	2881	2891
DIKVLDLNDN	KPVFETSSYD	TIIMEGMPVG	TKLTQVRAID	MDWGANGQVT	YSLHSDSQPE	KVMEAFNIDS	NTGWISTLKD	LDHETDPTFT	FSVVASDLGE
2901	2911	2921	2931	2941	2951	2961	2971	2981	2991
AFSLSSTALV	SVRVTDINDN	APVFAQEVYR	GNVKESDPPG	EVVAVLSTWD	RDTSDVNRQV	SYHITGGNPR	GRFALGLVQS	EWKVYVKRPL	DREEQDIYFL
3001	3011	3021	3031	3041	3051	3061	3071	3081	3091
NITATDGLFV	TQAMVEVSVS	DVNDNSPVCD	QVAYTALLPE	DIPSNKIILK	VSAKDADIGS	NGYIRYSLYG	SGNSEFFLDP	ESGELKTLAL	LDRERIPVYS
3101	3111	3121	3131	3141	3151	3161	3171	3181	3191
LMAKATDGGG	RFCQSNIHLI	LEDVNDNPPV	FSSDHYNTCV	YENTATKALL	TRVQAVDPDI	GINRKVVYSL	ADSAGGVFSI	DSSSGIIILE	QPLDREQQSS
3201	3211	3221	3231	3241	3251	3261	3271	3281	3291
YNISVRATDQ	SPGQSLSSLT	TVTITVLDIN	DNPPVFERRD	YLVTVPEDTS	PGTQVLAVFA	TSKDIGTNAE	ITYLIRSGNE	QGKFKINPKT	GGISVSEVLD
3301	3311	3321	3331	3341	3351	3361	3371	3381	3391
YELCKRFYLV	VEAKDGGTPA	LSAVATVNIN	LTDVNDNPPK	FSQDVYSAVI	SEDALVGDSV	ILLIAEDVDS	QPNGQIHFSI	VNGDRDNEFT	VDPVLGLVKV
3401	3411	3421	3431	3441	3451	3461	3471	3481	3491
KKKLDRERVS	GYSLLVQAVD	SGIPAMSSTA	TVNIDISDVN	DNSPVFTPAN	YTAVIQENKP	VGTSILQLVV	TDRDSFHNGP	PFSFSILSGN	EEEEFVLDPH
3501	3511	3521	3531	3541	3551	3561	3571	3581	3591
GILRSAVVFQ	HTESLEYVLC	VQAKDSGKPQ	QVSHTYIRVR	VIEESTHKPT	AIPLEIFIVT	MEDDFPGGVI	GKIHATDQDM	YDVLTFALKS	EQKSLFKVNS
3601	3611	3621	3631	3641	3651	3661	3671	3681	3691
HDGKIIALGG	LDSGKYVLNV	SVSDGRFQVP	IDVVVHVEQL	VHEMLQNTVT	IRFENVSPED	FVGLHMHGFR	RTLRNAVLTQ	KQDSLRIISI	QPVAGTNQLD
3701	3711	3721	3731	3741	3751	3761	3771	3781	3791
MLFAVEMHSS	EFYKPAYLIQ	KLSNARRHLE	NIMRISAILE	KNCSGLDCQE	QHCEQGLSLD	SHALMTYSTA	RISFVCPRFY	RNVRCTCNGG	LCPGSNDPCV
3801	3811	3821	3831	3841	3851	3861	3871	3881	3891
EKPCPGDMQC	VSYEASRRPF	LCQCPPGKLG	ECSGHTSLSF	AGNSYIKYRL	SENSKEEDFK	LALRLRTLQS	NGIIMYTRAN	PCIILKIVDG	KLWFQLDCGS
3901	3911	3921	3931	3941	3951	3961	3971	3981	3991
GPGILGISGR	AVNDGSWHSV	FLELNRNFTS	LSLDDSYVER	RRAPLYFQTL	STESSIYFGA	LVQADNIRSL	TDTRVTQVLS	GFQGCLDSVI	LNNNELPLQN
4001	4011	4021	4031	4041	4051	4061	4071	4081	4091
KRSSFAEVVG	LTELKLGCVL	YPDACKRSPC	QHGGSCTGLP	SGGYQCTCLS	QFTGRNCESE	ITACFPNPCR	NGGSCDPIGN	TFICNCKAGL	TGVTCEEDIN
4101	4111	4121	4131	4141	4151	4161	4171	4181	4191
ECEREECENG	GSCVNVFGSF	LCNCTPGYVG	QYCGLRPVVV	PNIQAGHSYV	GKEELIGIAV	VLFVIFILVV	LFIVFRKKVF	RKNYSRNNIT	LVQDPATAAL
4201	4211	4221	4231	4241	4251	4261	4271	4281	4291
LNKSNGIPFR	NLRGSGDGRN	VYQEVGPPQV	PVRPMAYTPC	FQSDSRSNLD	KIVDGLGGEH	QEMTTFHPES	PRILTARRGV	VVCSVAPNLP	AVSPCRSDCD
4301	4311	4321	4331	4341	4351	4361	4371	4381	4391
SIRKNGWDAG	TENKGVDDPG	EVTCFAGSNK	GSNSEVQSLS	SFQSDSGDDN	ASIVTVIQLV	NNVVDTIENE	VSVMDQGQNY	NRAYHWDTSD	WMPGARLSDI
4401	4411	4421	4431	4441	4451	4461	4471	4481	4491
EEVPNYENQD	GGSAHQGSTR	ELESDYYLGG	YDIDSEYPPP	HEEEFLSQDQ	LPPPLPEDFP	DQYEALPPSQ	PVSLASTLSP	DCRRRPQFHP	SQYLPPHPFP
4501	4511	4521	4531	4541	4551	4561	4571	4581
NETDLVGPPA	SCEFSTFAVS	MNQGTEPTGP	ADSVSLSLHN	SRGTSSSDVS	ANCGFDDSEV	AMSDYESVGE	LSLASLHIPF	VETQHQTQV

UniProtKB-Q8TDW7

Glycosites

Sequence

Reference

ID	Publication
1	Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
16	Deeb SJ, Cox J, Schmidt-Supprian M, Mann M: N-linked Glycosylation Enrichment for In-depth Cell Surface Proteomics of Diffuse Large B-cell Lymphoma Subtypes. Molecular & Cellular Proteomics 2014, 13:240-251.
33	Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.