Detail

UniProtKB-Q8WUJ3


Protein	Cell migration-inducing and hyaluronan-binding protein
Gene	CEMIP
Status	Reviewed
Source	Colorectal cancer cell line, HCT-116 (colorectal cancer); HCC cell lines (Liver); Non-small Cell Lung Carcinoma; Ovarian tumor
Years	2011-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
165	LSWTFLnK	2013(40); 2015(unpublished);
889	GIQLYDGPINIQnCTFR	2011(58); 2014(18); 2015(unpublished);
921	LNNAWQSCPHNnVTGIAFEDVPITSR	2014(18);

Sequence

1	11	21	31	41	51	61	71	81	91
MGAAGRQDFL	FKAMLTISWL	TLTCFPGATS	TVAAGCPDQS	PELQPWNPGH	DQDHHVHIGQ	GKTLLLTSSA	TVYSIHISEG	GKLVIKDHDE	PIVLRTRHIL
101	111	121	131	141	151	161	171	181	191
IDNGGELHAG	SALCPFQGNF	TIILYGRADE	GIQPDPYYGL	KYIGVGKGGA	LELHGQKKLS	WTFLNKTLHP	GGMAEGGYFF	ERSWGHRGVI	VHVIDPKSGT
201	211	221	231	241	251	261	271	281	291
VIHSDRFDTY	RSKKESERLV	QYLNAVPDGR	ILSVAVNDEG	SRNLDDMARK	AMTKLGSKHF	LHLGFRHPWS	FLTVKGNPSS	SVEDHIEYHG	HRGSAAARVF
301	311	321	331	341	351	361	371	381	391
KLFQTEHGEY	FNVSLSSEWV	QDVEWTEWFD	HDKVSQTKGG	EKISDLWKAH	PGKICNRPID	IQATTMDGVN	LSTEVVYKKG	QDYRFACYDR	GRACRSYRVR
401	411	421	431	441	451	461	471	481	491
FLCGKPVRPK	LTVTIDTNVN	STILNLEDNV	QSWKPGDTLV	IASTDYSMYQ	AEEFQVLPCR	SCAPNQVKVA	GKPMYLHIGE	EIDGVDMRAE	VGLLSRNIIV
501	511	521	531	541	551	561	571	581	591
MGEMEDKCYP	YRNHICNFFD	FDTFGGHIKF	ALGFKAAHLE	GTELKHMGQQ	LVGQYPIHFH	LAGDVDERGG	YDPPTYIRDL	SIHHTFSRCV	TVHGSNGLLI
601	611	621	631	641	651	661	671	681	691
KDVVGYNSLG	HCFFTEDGPE	ERNTFDHCLG	LLVKSGTLLP	SDRDSKMCKM	ITEDSYPGYI	PKPRQDCNAV	STFWMANPNN	NLINCAAAGS	EETGFWFIFH
701	711	721	731	741	751	761	771	781	791
HVPTGPSVGM	YSPGYSEHIP	LGKFYNNRAH	SNYRAGMIID	NGVKTTEASA	KDKRPFLSII	SARYSPHQDA	DPLKPREPAI	IRHFIAYKNQ	DHGAWLRGGD
801	811	821	831	841	851	861	871	881	891
VWLDSCRFAD	NGIGLTLASG	GTFPYDDGSK	QEIKNSLFVG	ESGNVGTEMM	DNRIWGPGGL	DHSGRTLPIG	QNFPIRGIQL	YDGPINIQNC	TFRKFVALEG
901	911	921	931	941	951	961	971	981	991
RHTSALAFRL	NNAWQSCPHN	NVTGIAFEDV	PITSRVFFGE	PGPWFNQLDM	DGDKTSVFHD	VDGSVSEYPG	SYLTKNDNWL	VRHPDCINVP	DWRGAICSGC
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
YAQMYIQAYK	TSNLRMKIIK	NDFPSHPLYL	EGALTRSTHY	QQYQPVVTLQ	KGYTIHWDQT	APAELAIWLI	NFNKGDWIRV	GLCYPRGTTF	SILSDVHNRL
1101	1111	1121	1131	1141	1151	1161	1171	1181	1191
LKQTSKTGVF	VRTLQMDKVE	QSYPGRSHYY	WDEDSGLLFL	KLKAQNEREK	FAFCSMKGCE	RIKIKALIPK	NAGVSDCTAT	AYPKFTERAV	VDVPMPKKLF
1201	1211	1221	1231	1241	1251	1261	1271	1281	1291
GSQLKTKDHF	LEVKMESSKQ	HFFHLWNDFA	YIEVDGKKYP	SSEDGIQVVV	IDGNQGRVVS	HTSFRNSILQ	GIPWQLFNYV	ATIPDNSIVL	MASKGRYVSR
1301	1311	1321	1331	1341	1351	1361
GPWTRVLEKL	GADRGLKLKE	QMAFVGFKGS	FRPIWVTLDT	EDHKAKIFQV	VPIPVVKKKK	L

Reference

ID	Publication
18	Hirao Y, Matsuzaki H, Iwaki J, Kuno A, Kaji H, Ohkura T, Togayachi A, Abe M, Nomura M, Noguchi M, et al: Glycoproteomics Approach for Identifying Glycobiomarker Candidate Molecules for Tissue Type Classification of Non-small Cell Lung Carcinoma. Journal of Proteome Research 2014, 13:4705-4716.
40	Li X, Jiang J, Zhao X, Wang J, Han H, Zhao Y, Peng B, Zhong R, Ying W, Qian X: N-glycoproteome Analysis of the Secretome of Human Metastatic Hepatocellular Carcinoma Cell Lines Combining Hydrazide Chemistry, HILIC Enrichment and Mass Spectrometry. Plos One 2013, 8.
58	Nagano K, Shinkawa T, Kato K, Inomata N, Yabuki N, Haramura M: Distinct cell surface proteome profiling by biotin labeling and glycoprotein capturing. Journal of Proteomics 2011, 74:1985-1993.