Detail

UniProtKB-Q92729


Protein	Receptor-type tyrosine-protein phosphatase U
Gene	PTPRU
Status	Reviewed
Source	Breast Cancer cell lines; Breast cancer cell lines; Breast tumor; HEK293 cell line (embryonic kidney); HEK293T cell line (embryonic kidney), HEK293T cell line (embryonic kidney); Lymphocytes; Non-small Cell Lung Carcinoma; Ovarian tumor; Prostate tumor
Years	2007-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
75	GSYIMVnTSQHAP	2013(37);
75	APADLPHGSYLMVnTSQHAPGQR	2015(unpublished);2007(unpublished);2007(unpublished);2007(unpublished);2007;
134	IGSAVWnMTGSHG	2013(37);
134	VNGGPLGSAVWnMTGSHGR	2015(unpublished);
410	WEPIGYnVTRCHT	2013(37);
410	QLTLQWEPLGYnVTR	2014(15); 2014(18);
548	LRnETYHVFSNLHPGTTYLFSVR	2015(9);
685	TVGDnQTYR	2015(unpublished);
685	GLVHYFGAELAASSLPEAMPFTVGDnQTYR	2015(unpublished);

Sequence

1	11	21	31	41	51	61	71	81	91
MARAQALVLA	LTFQLCAPET	ETPAAGCTFE	EASDPAVPCE	YSQAQYDDFQ	WEQVRIHPGT	RAPADLPHGS	YLMVNTSQHA	PGQRAHVIFQ	SLSENDTHCV
101	111	121	131	141	151	161	171	181	191
QFSYFLYSRD	GHSPGTLGVY	VRVNGGPLGS	AVWNMTGSHG	RQWHQAELAV	STFWPNEYQV	LFEALISPDR	RGYMGLDDIL	LLSYPCAKAP	HFSRLGDVEV
201	211	221	231	241	251	261	271	281	291
NAGQNASFQC	MAAGRAAEAE	RFLLQRQSGA	LVPAAGVRHI	SHRRFLATFP	LAAVSRAEQD	LYRCVSQAPR	GAGVSNFAEL	IVKEPPTPIA	PPQLLRAGPT
301	311	321	331	341	351	361	371	381	391
YLIIQLNTNS	IIGDGPIVRK	EIEYRMARGP	WAEVHAVSLQ	TYKLWHLDPD	TEYEISVLLT	RPGDGGTGRP	GPPLISRTKC	AEPMRAPKGL	AFAEIQARQL
401	411	421	431	441	451	461	471	481	491
TLQWEPLGYN	VTRCHTYTVS	LCYHYTLGSS	HNQTIRECVK	TEQGVSRYTI	KNLLPYRNVH	VRLVLTNPEG	RKEGKEVTFQ	TDEDVPSGIA	AESLTFTPLE
501	511	521	531	541	551	561	571	581	591
DMIFLKWEEP	QEPNGLITQY	EISYQSIESS	DPAVNVPGPR	RTISKLRNET	YHVFSNLHPG	TTYLFSVRAR	TGKGFGQAAL	TEITTNISAP	SFDYADMPSP
601	611	621	631	641	651	661	671	681	691
LGESENTITV	LLRPAQGRGA	PISVYQVIVE	EERARRLRRE	PGGQDCFPVP	LTFEAALARG	LVHYFGAELA	ASSLPEAMPF	TVGDNQTYRG	FWNPPLEPRK
701	711	721	731	741	751	761	771	781	791
AYLIYFQAAS	HLKGETRLNC	IRIARKAACK	ESKRPLEVSQ	RSEEMGLILG	ICAGGLAVLI	LLLGAIIVII	RKGRDHYAYS	YYPKPVNMTK	ATVNYRQEKT
801	811	821	831	841	851	861	871	881	891
HMMSAVDRSF	TDQSTLQEDE	RLGLSFMDTH	GYSTRGDQRS	GGVTEASSLL	GGSPRRPCGR	KGSPYHTGQL	HPAVRVADLL	QHINQMKTAE	GYGFKQEYES
901	911	921	931	941	951	961	971	981	991
FFEGWDATKK	KDKVKGSRQE	PMPAYDRHRV	KLHPMLGDPN	ADYINANYID	GYHRSNHFIA	TQGPKPEMVY	DFWRMVWQEH	CSSIVMITKL	VEVGRVKCSR
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
YWPEDSDTYG	DIKIMLVKTE	TLAEYVVRTF	ALERRGYSAR	HEVRQFHFTA	WPEHGVPYHA	TGLLAFIRRV	KASTPPDAGP	IVIHCSAGTG	RTGCYIVLDV
1101	1111	1121	1131	1141	1151	1161	1171	1181	1191
MLDMAECEGV	VDIYNCVKTL	CSRRVNMIQT	EEQYIFIHDA	ILEACLCGET	TIPVSEFKAT	YKEMIRIDPQ	SNSSQLREEF	QTLNSVTPPL	DVEECSIALL
1201	1211	1221	1231	1241	1251	1261	1271	1281	1291
PRNRDKNRSM	DVLPPDRCLP	FLISTDGDSN	NYINAALTDS	YTRSAAFIVT	LHPLQSTTPD	FWRLVYDYGC	TSIVMLNQLN	QSNSAWPCLQ	YWPEPGRQQY
1301	1311	1321	1331	1341	1351	1361	1371	1381	1391
GLMEVEFMSG	TADEDLVARV	FRVQNISRLQ	EGHLLVRHFQ	FLRWSAYRDT	PDSKKAFLHL	LAEVDKWQAE	SGDGRTIVHC	LNGGGRSGTF	CACATVLEMI
1401	1411	1421	1431	1441
RCHNLVDVFF	AAKTLRNYKP	NMVETMDQYH	FCYDVALEYL	EGLESR

Reference

ID	Publication
9	Smeekens JM, Chen WX, Wu RH: Mass Spectrometric Analysis of the Cell Surface N-Glycoproteome by Combining Metabolic Labeling and Click Chemistry. Journal of the American Society for Mass Spectrometry 2015, 26:604-614.
15	Chen R, Seebun D, Ye M, Zou H, Figeys D: Site-specific characterization of cell membrane N-glycosylation with integrated hydrophilic interaction chromatography solid phase extraction and LC-MS/MS. Journal of Proteomics 2014, 103:194-203.
18	Hirao Y, Matsuzaki H, Iwaki J, Kuno A, Kaji H, Ohkura T, Togayachi A, Abe M, Nomura M, Noguchi M, et al: Glycoproteomics Approach for Identifying Glycobiomarker Candidate Molecules for Tissue Type Classification of Non-small Cell Lung Carcinoma. Journal of Proteome Research 2014, 13:4705-4716.
37	Boersema PJ, Geiger T, Wisniewski JR, Mann M: Quantification of the N-glycosylated Secretome by Super-SILAC During Breast Cancer Progression and in Human Blood Samples. Molecular & Cellular Proteomics 2013, 12:158-171.