Detail


Protein	Piezo-type mechanosensitive ion channel component 2
Gene	PIEZO2
Status	Reviewed
Source	DLBCL cell lines (Diffuse large B-cell lymphoma); Hela cell line (cervical cancer)
Years	2014-2015

Site	Identified Peptides	Year(Publication ID)
95	IAPGYnCSTWEK	2015(12);
2572	MIAGnSTESSKTPVTIEK	2014(16); 2015(12);

Sequence

1	11	21	31	41	51	61	71	81	91
MASEVVCGLI	FRLLLPICLA	VACAFRYNGL	SFVYLIYLLL	IPLFSEPTKT	TMQGHTGRLL	KSLCFISLSF	LLLHIIFHIT	LVSLEAQHRI	APGYNCSTWE
101	111	121	131	141	151	161	171	181	191
KTFRQIGFES	LKGADAGNGI	RVFVPDIGMF	IASLTIWLLC	RNIVQKPVTD	EAAQSNPEFE	NEELAEGEKI	DSEEALIYEE	DFNGGDGVEG	ELEESTKLKM
201	211	221	231	241	251	261	271	281	291
FRRLASVASK	LKEFIGNMIT	TAGKVVVTIL	LGSSGMMLPS	LTSSVYFFVF	LGLCTWWSWC	RTFDPLLFSC	LCVLLAIFTA	GHLIGLYLYQ	FQFFQEAVPP
301	311	321	331	341	351	361	371	381	391
NDYYARLFGI	KSVIQTDCSS	TWKIIVNPDL	SWYHHANPIL	LLVMYYTLAT	LIRIWLQEPL	VQDEGTKEED	KALACSPIQI	TAGRRRSLWY	ATHYPTDERK
401	411	421	431	441	451	461	471	481	491
LLSMTQDDYK	PSDGLLVTVN	GNPVDYHTIH	PSLPMENGPG	KADLYSTPQY	RWEPSDESSE	KREEEEEEKE	EFEEERSREE	KRSIKVHAMV	SVFQFIMKQS
501	511	521	531	541	551	561	571	581	591
YICALIAMMA	WSITYHSWLT	FVLLIWSCTL	WMIRNRRKYA	MISSPFMVVY	GNLLLILQYI	WSFELPEIKK	VPGFLEKKEP	GELASKILFT	ITFWLLLRQH
601	611	621	631	641	651	661	671	681	691
LTEQKALQEK	EALLSEVKIG	SQENEEKDEE	LQDIQVEGEP	KEEEEEEAKE	EKQERKKVEQ	EEAEEEDEQD	IMKVLGNLVV	AMFIKYWIYV	CGGMFFFVSF
701	711	721	731	741	751	761	771	781	791
EGKIVMYKII	YMVLFLFCVA	LYQVHYEWWR	KILKYFWMSV	VIYTMLVLIF	IYTYQFENFP	GLWQNMTGLK	KEKLEDLGLK	QFTVAELFTR	IFIPTSFLLV
801	811	821	831	841	851	861	871	881	891
CILHLHYFHD	RFLELTDLKS	IPSKEDNTIY	RLAHPEGSLP	DLTMMHLTAS	LEKPEVRKLA	EPGEEKLEGY	SEKAQKGDLG	KDSEESEEDG	EEEEESEEEE
901	911	921	931	941	951	961	971	981	991
ETSDLRNKWH	LVIDRLTVLF	LKFLEYFHKL	QVFMWWILEL	HIIKIVSSYI	IWVSVKEVSL	FNYVFLISWA	FALPYAKLRR	LASSVCTVWT	CVIIVCKMLY
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
QLQTIKPENF	SVNCSLPNEN	QTNIPFNELN	KSLLYSAPID	PTEWVGLRKS	SPLLVYLRNN	LLMLAILAFE	VTIYRHQEYY	RGRNNLTAPV	SRTIFHDITR
1101	1111	1121	1131	1141	1151	1161	1171	1181	1191
LHLDDGLINC	AKYFINYFFY	KFGLETCFLM	SVNVIGQRMD	FYAMIHACWL	IAVLYRRRRK	AIAEIWPKYC	CFLACIITFQ	YFICIGIPPA	PCRDYPWRFK
1201	1211	1221	1231	1241	1251	1261	1271	1281	1291
GASFNDNIIK	WLYFPDFIVR	PNPVFLVYDF	MLLLCASLQR	QIFEDENKAA	VRIMAGDNVE	ICMNLDAASF	SQHNPVPDFI	HCRSYLDMSK	VIIFSYLFWF
1301	1311	1321	1331	1341	1351	1361	1371	1381	1391
VLTIIFITGT	TRISIFCMGY	LVACFYFLLF	GGDLLLKPIK	SILRYWDWLI	AYNVFVITMK	NILSIGACGY	IGTLVHNSCW	LIQAFSLACT	VKGYQMPAAN
1401	1411	1421	1431	1441	1451	1461	1471	1481	1491
SPCTLPSGEA	GIIWDSICFA	FLLLQRRVFM	SYYFLHVVAD	IKASQILASR	GAELFQATIV	KAVKARIEEE	KKSMDQLKRQ	MDRIKARQQK	YKKGKERMLS
1501	1511	1521	1531	1541	1551	1561	1571	1581	1591
LTQEPGEGQD	MQKLSEEDDE	READKQKAKG	KKKQWWRPWV	DHASMVRSGD	YYLFETDSEE	EEEEELKKED	EEPPRRSAFQ	FVYQAWITDP	KTALRQRHKE
1601	1611	1621	1631	1641	1651	1661	1671	1681	1691
KKRSAREERK	RRRKGSKEGP	VEWEDREDEP	IKKKSDGPDN	IIKRIFNILK	FTWVLFLATV	DSFTTWLNSI	SREHIDISTV	LRIERCMLTR	EIKKGNVPTR
1701	1711	1721	1731	1741	1751	1761	1771	1781	1791
ESIHMYYQNH	IMNLSRESGL	DTIDEHPGAA	SGAQTAHRMD	SLDSHDSISS	EPTQCTMLYS	RQGTTETIEE	VEAEQEEEAG	STAPEPREAK	EYEATGYDVG
1801	1811	1821	1831	1841	1851	1861	1871	1881	1891
AMGAEEASLT	PEEELTQFST	LDGDVEAPPS	YSKAVSFEHL	SFGSQDDSAG	KNRMAVSPDD	SRTDKLGSSI	LPPLTHELTA	SELLLKKMFH	DDELEESEKF
1901	1911	1921	1931	1941	1951	1961	1971	1981	1991
YVGQPRFLLL	FYAMYNTLVA	RSEMVCYFVI	ILNHMVSASM	ITLLLPILIF	LWAMLSVPRP	SRRFWMMAIV	YTEVAIVVKY	FFQFGFFPWN	KNVEVNKDKP
2001	2011	2021	2031	2041	2051	2061	2071	2081	2091
YHPPNIIGVE	KKEGYVLYDL	IQLLALFFHR	SILKCHGLWD	EDDMTESGMA	REESDDELSL	GHGRRDSSDS	LKSINLAASV	ESVHVTFPEQ	QTAVRRKRSG
2101	2111	2121	2131	2141	2151	2161	2171	2181	2191
SSSEPSQRSS	FSSNRSQRGS	TSTRNSSQKG	SSVLSIKQKG	KRELYMEKLQ	EHLIKAKAFT	IKKTLEIYVP	IKQFFYNLIH	PEYSAVTDVY	VLMFLADTVD
2201	2211	2221	2231	2241	2251	2261	2271	2281	2291
FIIIVFGFWA	FGKHSAAADI	TSSLSEDQVP	GPFLVMVLIQ	FGTMVVDRAL	YLRKTVLGKV	IFQVILVFGI	HFWMFFILPG	VTERKFSQNL	VAQLWYFVKC
2301	2311	2321	2331	2341	2351	2361	2371	2381	2391
VYFGLSAYQI	RCGYPTRVLG	NFLTKSYNYV	NLFLFQGFRL	VPFLTELRAV	MDWVWTDTTL	SLSSWICVED	IYAHIFILKC	WRESEKRYPQ	PRGQKKKKVV
2401	2411	2421	2431	2441	2451	2461	2471	2481	2491
KYGMGGMIIV	LLICIVWFPL	LFMSLIKSVA	GVINQPLDVS	VTITLGGYQP	IFTMSAQQSQ	LKVMDQQSFN	KFIQAFSRDT	GAMQFLENYE	KEDITVAELE
2501	2511	2521	2531	2541	2551	2561	2571	2581	2591
GNSNSLWTIS	PPSKQKMIHE	LLDPNSSFSV	VFSWSIQRNL	SLGAKSEIAT	DKLSFPLKNI	TRKNIAKMIA	GNSTESSKTP	VTIEKIYPYY	VKAPSDSNSK
2601	2611	2621	2631	2641	2651	2661	2671	2681	2691
PIKQLLSENN	FMDITIILSR	DNTTKYNSEW	WVLNLTGNRI	YNPNSQALEL	VVFNDKVSPP	SLGFLAGYGI	MGLYASVVLV	IGKFVREFFS	GISHSIMFEE
2701	2711	2721	2731	2741	2751
LPNVDRILKL	CTDIFLVRET	GELELEEDLY	AKLIFLYRSP	ETMIKWTREK	TN

UniProtKB-Q9H5I5

Glycosites

Sequence

Reference

ID	Publication
12	Weng Y, Sui Z, Jiang H, Shan Y, Chen L, Zhang S, Zhang L, Zhang Y: Releasing N-glycan from Peptide N-terminus by N-terminal Succinylation Assisted Enzymatic Deglycosylation. Scientific Reports 2015, 5.
16	Deeb SJ, Cox J, Schmidt-Supprian M, Mann M: N-linked Glycosylation Enrichment for In-depth Cell Surface Proteomics of Diffuse Large B-cell Lymphoma Subtypes. Molecular & Cellular Proteomics 2014, 13:240-251.