Contains      

UniProtKB-Q9H9K5

Protein Endogenous retrovirus group MER34 member 1 Env polyprotein
Gene ERVMER34-1
Status Reviewed
Source 22Rv1 cell line (prostate cancer); Breast Cancer cell lines; Breast cancer xenografts; HuH-7 cell line (Liver); Non-small Cell Lung Carcinoma; Ovarian tumor; Prostate tumor; Urine
Years 2007-2015

Glycosites

Site Identified Peptides Year(Publication ID)
89 PQAEVQnHSTSSY 2013(37);
89 VWYPQAEVQnHSTSSYR 2015(unpublished);2015(unpublished);2015(unpublished);
89 VWYPQAEVQnHSTSSYRK 2013(38);
192 CTnRTWNSSAVPI 2013(37);
192 WFAGCTnRTWNSS 2013(37);
196 CTNRTWnSSAVPI 2013(37);
196 WFAGCTNRTWnSS 2013(37);
196 TWnSSAVPLIGLPNTQDYK 2015(unpublished);
225 GITWSGnDTCIYS 2013(37);
225 WVDRNSGLTWSGnDTCLYSCQNQTK 2013(38); 2014(18);
234 CIYSCQnQTKGII 2013(37);
234 WVDRNSGLTWSGNDTCLYSCQnQTK 2013(38); 2014(18);
333 TRYITInASQITN 2013(37);
333 YLTLnASQITNLR 2007(50); 2012(18); 2014(unpublished);2015(unpublished);2015(unpublished);2015;2015;2007;2007;2007;
369 CTQGDTDNPPLYCNPKDnSTIR 2014(18);
390 AILnISK 2015(unpublished);2015(unpublished);2015(unpublished);2015(unpublished);
390 AILnISKAMEQEFSATK 2014(18);
449 QCCIYInYSEEIK 2013(37);

Sequence

1112131415161718191
MGSLSNYALLQLTLTAFLTILVQPQHLLAPVFRTLSILTNQSNCWLCEHLDNAEQPELVFVPASASTWWTYSGQWMYERVWYPQAEVQNHSTSSYRKVTW
101111121131141151161171181191
HWEASMEAQGLSFAQVRLLEGNFSLCVENKNGSGPFLGNIPKQYCNQILWFDSTDGTFMPSIDVTNESRNDDDDTSVCLGTRQCSWFAGCTNRTWNSSAV
201211221231241251261271281291
PLIGLPNTQDYKWVDRNSGLTWSGNDTCLYSCQNQTKGLLYQLFRNLFCSYGLTEAHGKWRCADASITNDKGHDGHRTPTWWLTGSNLTLSVNNSGLFFL
301311321331341351361371381391
CGNGVYKGFPPKWSGRCGLGYLVPSLTRYLTLNASQITNLRSFIHKVTPHRCTQGDTDNPPLYCNPKDNSTIRALFPSLGTYDLEKAILNISKAMEQEFS
401411421431441451461471481491
ATKQTLEAHQSKVSSLASASRKDHVLDIPTTQRQTACGTVGKQCCLYINYSEEIKSNIQRLHEASENLKNVPLLDWQGIFAKVGDWFRSWGYVLLIVLFC
501511521531541551561
LFIFVLIYVRVFRKSRRSLNSQPLNLALSPQQSAQLLVSETSCQVSNRAMKGLTTHQYDTSLL

Reference

ID Publication
18Hirao Y, Matsuzaki H, Iwaki J, Kuno A, Kaji H, Ohkura T, Togayachi A, Abe M, Nomura M, Noguchi M, et al: Glycoproteomics Approach for Identifying Glycobiomarker Candidate Molecules for Tissue Type Classification of Non-small Cell Lung Carcinoma. Journal of Proteome Research 2014, 13:4705-4716.
37Boersema PJ, Geiger T, Wisniewski JR, Mann M: Quantification of the N-glycosylated Secretome by Super-SILAC During Breast Cancer Progression and in Human Blood Samples. Molecular & Cellular Proteomics 2013, 12:158-171.
38Kaji H, Ocho M, Togayachi A, Kuno A, Sogabe M, Ohkura T, Nozaki H, Angata T, Chiba Y, Ozaki H, et al: Glycoproteomic Discovery of Serological Biomarker Candidates for HCV/HBV Infection-Associated Liver Fibrosis and Hepatocellular Carcinoma. Journal of Proteome Research 2013, 12:2630-2640.
50Whitmore TE, Peterson A, Holzman T, Eastham A, Amon L, McIntosh M, Ozinsky A, Nelson PS, Martin DB: Integrative Analysis of N-Linked Human Glycoproteomic Data Sets Reveals PTPRF Ectodomain as a Novel Plasma Biomarker Candidate for Prostate Cancer. Journal of Proteome Research 2012, 11:2653-2665.