Contains      

UniProtKB-Q9HBB8

Protein Cadherin-related family member 5
Gene CDHR5
Status Reviewed
Source Colorectal tumor; HCC cell lines (Liver); Liver; Liver tumor (HCC); Ovarian tumor; Plasma; Prostate tumor; Serum; Urine
Years 2005-2015

Glycosites

Site Identified Peptides Year(Publication ID)
44 NTnVTEPLVDIHVPE 2013(42); 2014(33);
44 VEENTnVTEPLVDIHVPE 2014(33);
81 IQGNQLFLnVTPDYEEK 2005( 81); 2007(45); 2013(22); 2014(33); 2014(unpublished);2015(unpublished);2015(unpublished);2015(unpublished);2007;2007;2007;2007;
140 DTKVnSTVIPE 2014(33);
140 VnSTVIPETQLQAEDR 2007(40); 2013(45); 2013(22); 2014(33); 2014(unpublished);2015(unpublished);2015;2007;2007;
140 VEEDTKVnSTVIPETQIQAEDR 2014(32); 2014(32);
140 VEEDTKVnSTVIPETQLQAEDR 2013(45); 2014(13); 2014(22); 2014(33); 2015(unpublished);2015(unpublished);2015(unpublished);2015(4);
140 VEEDTKVnSTVIPETQLQAEDRDK 2015(unpublished);2015(unpublished);
140 EIRVEEDTKVnSTVIPETQLQAEDR 2015(unpublished);2015(unpublished);
198 LDRPLDFYERPnMTFWLLVR 2015(unpublished);
297 GNVnGTFIIHPD 2014(33);
297 GNVnGTFIIHPDSGNITVAR 2014(32);
297 GNVnGTFIIHPDSGNLTVAR 2005( 81); 2007(42); 2013(45); 2013(13); 2014(22); 2014(33); 2014(unpublished);2015(unpublished);2015(unpublished);2015;2007;2007;2007;
308 GNVNGTFIIHPDSGnITVAR 2014(32);
308 GNVNGTFIIHPDSGnLTVAR 2005( 81); 2007(42); 2013(45); 2013(13); 2014(22); 2014(33); 2014(unpublished);2015(unpublished);2015(unpublished);2015;2007;2007;2007;
405 ITnHSHFR 2014(22); 2014(33); 2015(unpublished);2015(unpublished);

Sequence

1112131415161718191
MGSWALLWPPLLFTGLLVRPPGTMAQAQYCSVNKDIFEVEENTNVTEPLVDIHVPEGQEVTLGALSTPFAFRIQGNQLFLNVTPDYEEKSLLEAQLLCQS
101111121131141151161171181191
GGTLVTQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQLQAEDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMT
201211221231241251261271281291
FWLLVRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPCTFSDGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYAEDGDRGINQPIIYSIFRGNVNGTF
301311321331341351361371381391
IIHPDSGNLTVARSVPSPMTFLLLVKGQQADLARYSVTQVTVEAVAAAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRIQAQDPEFSDLNSAIT
401411421431441451461471481491
YRITNHSHFRMEGEVVLTTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWTSTTSEVPRPPEPSQGPSTTSSGGGT
501511521531541551561571581591
GPHPPSGTTLRPPTSSTPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPATPGGG
601611621631641651661671681691
TAQTPEAGTSQPMPPGMGTSTSHQPTTPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPRLKC
701711721731741751761771781791
CCGKAPEPQPQGFDNQAFLPDHKANWAPVPSPTHDPKPAEAPMPAEPAPPGPASPGGAPEPPAAARAGGSPTAVRSILTKERRPEGGYKAVWFGEDIGTE
801811821831841
ADVVVLNAPTLDVDGASDSGSGDEGEGAGRGGGPYDAPGGDDSYI

Reference

ID Publication
4Cheow ESH, Sim KH, de Kleijn D, Lee CN, Sorokin V, Sze SK: Simultaneous Enrichment of Plasma Soluble and Extracellular Vesicular Glycoproteins Using Prolonged Ultracentrifugation-Electrostatic Repulsion-hydrophilic Interaction Chromatography (PUC-ERLIC) Approach. Molecular & Cellular Proteomics 2015, 14:1657-1671.
13Yang W, Laeyendecker O, Wendel SK, Zhang B, Sun S, Zhou J-Y, Ao M, Moore RD, Jackson JB, Zhang H: Glycoproteomic Study Reveals Altered Plasma Proteins Associated with HIV Elite Suppressors. Theranostics 2014, 4:1153.
22Nicastri A, Gaspari M, Sacco R, Elia L, Gabriele C, Romano R, Rizzuto A, Cuda G: N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue. Journal of Proteome Research 2014, 13:4932-4941.
32Zhang Z, Sun Z, Zhu J, Liu J, Huang G, Ye M, Zou H: High-Throughput Determination of the Site-Specific N-Sialoglycan Occupancy Rates by Differential Oxidation of Glycoproteins Followed with Quantitative Glycoproteomics Analysis. Analytical Chemistry 2014, 86:9830-9837.
33Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.
40Li X, Jiang J, Zhao X, Wang J, Han H, Zhao Y, Peng B, Zhong R, Ying W, Qian X: N-glycoproteome Analysis of the Secretome of Human Metastatic Hepatocellular Carcinoma Cell Lines Combining Hydrazide Chemistry, HILIC Enrichment and Mass Spectrometry. Plos One 2013, 8.
42Ma C, Zhao X, Han H, Tong W, Zhang Q, Qin P, Chang C, Peng B, Ying W, Qian X: N-linked glycoproteome profiling of human serum using tandem enrichment and multiple fraction concatenation. Electrophoresis 2013, 34:2440-2450.
45Zhou H, Froehlich JW, Briscoe AC, Lee RS: The GlycoFilter: A Simple and Comprehensive Sample Preparation Platform for Proteomics, N-Glycomics and Glycosylation Site Assignment. Molecular & Cellular Proteomics 2013, 12:2981-2991.