| Protein | Transmembrane protein 8A |
| Gene | TMEM8A |
| Status | Reviewed |
| Source | Breast cancer xenografts; Colorectal tumor; DLBCL cell lines (Diffuse large B-cell lymphoma); Hela cell line (cervical cancer); Jurkat T cell line; Liver; OVCAR-3 cell line (Ovarian cancer); Pancreatic islets; Urine |
| Years | 2012-2015 |
| Site | Identified Peptides | Year(Publication ID) |
|---|---|---|
| 232 | DCVSnGSIGCPVR | 2014(16); |
| 232 | DCVSnGSLGCPVR | 2012(48); 2014(13); 2014(22); 2014(33); 2015(unpublished);2015(unpublished);2015(unpublished);2015(unpublished);2015(12); |
| 323 | nASSGLLSPSPDHQDLGR | 2015(1); |
| 535 | nSTAQTVAQQR | 2015(1); |
| 535 | GWSCTDnSTAQTVAQQR | 2012(48); |
| 1 | 11 | 21 | 31 | 41 | 51 | 61 | 71 | 81 | 91 |
| MGRAGTGTGG | EAVAAVVAGP | LLLLLLARPP | PASAGYSGKS | EVGLVSEHFS | QAPQRLSFYS | WYGSARLFRF | RVPPDAVLLR | WLLQVSRESG | AACTDAEITV |
| 101 | 111 | 121 | 131 | 141 | 151 | 161 | 171 | 181 | 191 |
| HFRSGAPPVI | NPLGTSFPDD | TAVQPSFQVG | VPLSTTPRSN | ASVNVSHPAP | GDWFVAAHLP | PSSQKIELKG | LAPTCAYVFQ | PELLVTRVVE | ISIMEPDVPL |
| 201 | 211 | 221 | 231 | 241 | 251 | 261 | 271 | 281 | 291 |
| PQTLLSHPSY | LKVFVPDYTR | ELLLELRDCV | SNGSLGCPVR | LTVGPVTLPS | NFQKVLTCTG | APWPCRLLLP | SPPWDRWLQV | TAESLVGPLG | TVAFSAVAAL |
| 301 | 311 | 321 | 331 | 341 | 351 | 361 | 371 | 381 | 391 |
| TACRPRSVTI | QPLLQSSQNQ | SFNASSGLLS | PSPDHQDLGR | SGRVDRSPFC | LTNYPVTRED | MDVVSVHFQP | LDRVSVRVCS | DTPSVMRLRL | NTGMDSGGSL |
| 401 | 411 | 421 | 431 | 441 | 451 | 461 | 471 | 481 | 491 |
| TISLRANKTE | MRNETVVVAC | VNAASPFLGF | NTSLNCTTAF | FQGYPLSLSA | WSRRANLIIP | YPETDNWYLS | LQLMCPENAE | DCEQAVVHVE | TTLYLVPCLN |
| 501 | 511 | 521 | 531 | 541 | 551 | 561 | 571 | 581 | 591 |
| DCGPYGQCLL | LRRHSYLYAS | CSCKAGWRGW | SCTDNSTAQT | VAQQRAATLL | LTLSNLMFLA | PIAVSVRRFF | LVEASVYAYT | MFFSTFYHAC | DQPGEAVLCI |
| 601 | 611 | 621 | 631 | 641 | 651 | 661 | 671 | 681 | 691 |
| LSYDTLQYCD | FLGSGAAIWV | TILCMARLKT | VLKYVLFLLG | TLVIAMSLQL | DRRGMWNMLG | PCLFAFVIMA | SMWAYRCGHR | RQCYPTSWQR | WAFYLLPGVS |
| 701 | 711 | 721 | 731 | 741 | 751 | 761 | 771 | ||
| MASVGIAIYT | SMMTSDNYYY | THSIWHILLA | GSAALLLPPP | DQPAEPWACS | QKFPCHYQIC | KNDREELYAV | T |
| ID | Publication |
|---|---|
| 1 | Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication. |
| 12 | Weng Y, Sui Z, Jiang H, Shan Y, Chen L, Zhang S, Zhang L, Zhang Y: Releasing N-glycan from Peptide N-terminus by N-terminal Succinylation Assisted Enzymatic Deglycosylation. Scientific Reports 2015, 5. |
| 13 | Yang W, Laeyendecker O, Wendel SK, Zhang B, Sun S, Zhou J-Y, Ao M, Moore RD, Jackson JB, Zhang H: Glycoproteomic Study Reveals Altered Plasma Proteins Associated with HIV Elite Suppressors. Theranostics 2014, 4:1153. |
| 16 | Deeb SJ, Cox J, Schmidt-Supprian M, Mann M: N-linked Glycosylation Enrichment for In-depth Cell Surface Proteomics of Diffuse Large B-cell Lymphoma Subtypes. Molecular & Cellular Proteomics 2014, 13:240-251. |
| 22 | Nicastri A, Gaspari M, Sacco R, Elia L, Gabriele C, Romano R, Rizzuto A, Cuda G: N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue. Journal of Proteome Research 2014, 13:4932-4941. |
| 33 | Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721. |
| 48 | Danzer C, Eckhardt K, Schmidt A, Fankhauser N, Ribrioux S, Wollscheid B, Mueller L, Schiess R, Zuellig R, Lehmann R, et al: Comprehensive Description of the N-Glycoproteome of Mouse Pancreatic beta-Cells and Human Islets. Journal of Proteome Research 2012, 11:1598-1608. |