Detail


Protein	Reticulon-4
Gene	RTN4
Status	Reviewed
Source	Liver; OVCAR-3 cell line (Ovarian cancer)
Years	2014-2015

Site	Identified Peptides	Year(Publication ID)
254	nLSTVLPTEGTLQENVSEASK	2015(1);
268	NLSTVLPTEGTLQEnVSEASK	2015(1);
1100	YSNSALGHVnCTIK	2014(33);

Sequence

1	11	21	31	41	51	61	71	81	91
MEDLDQSPLV	SSSDSPPRPQ	PAFKYQFVRE	PEDEEEEEEE	EEEDEDEDLE	ELEVLERKPA	AGLSAAPVPT	APAAGAPLMD	FGNDFVPPAP	RGPLPAAPPV
101	111	121	131	141	151	161	171	181	191
APERQPSWDP	SPVSSTVPAP	SPLSAAAVSP	SKLPEDDEPP	ARPPPPPPAS	VSPQAEPVWT	PPAPAPAAPP	STPAAPKRRG	SSGSVDETLF	ALPAASEPVI
201	211	221	231	241	251	261	271	281	291
RSSAENMDLK	EQPGNTISAG	QEDFPSVLLE	TAASLPSLSP	LSAASFKEHE	YLGNLSTVLP	TEGTLQENVS	EASKEVSEKA	KTLLIDRDLT	EFSELEYSEM
301	311	321	331	341	351	361	371	381	391
GSSFSVSPKA	ESAVIVANPR	EEIIVKNKDE	EEKLVSNNIL	HNQQELPTAL	TKLVKEDEVV	SSEKAKDSFN	EKRVAVEAPM	REEYADFKPF	ERVWEVKDSK
401	411	421	431	441	451	461	471	481	491
EDSDMLAAGG	KIESNLESKV	DKKCFADSLE	QTNHEKDSES	SNDDTSFPST	PEGIKDRSGA	YITCAPFNPA	ATESIATNIF	PLLGDPTSEN	KTDEKKIEEK
501	511	521	531	541	551	561	571	581	591
KAQIVTEKNT	STKTSNPFLV	AAQDSETDYV	TTDNLTKVTE	EVVANMPEGL	TPDLVQEACE	SELNEVTGTK	IAYETKMDLV	QTSEVMQESL	YPAAQLCPSF
601	611	621	631	641	651	661	671	681	691
EESEATPSPV	LPDIVMEAPL	NSAVPSAGAS	VIQPSSSPLE	ASSVNYESIK	HEPENPPPYE	EAMSVSLKKV	SGIKEEIKEP	ENINAALQET	EAPYISIACD
701	711	721	731	741	751	761	771	781	791
LIKETKLSAE	PAPDFSDYSE	MAKVEQPVPD	HSELVEDSSP	DSEPVDLFSD	DSIPDVPQKQ	DETVMLVKES	LTETSFESMI	EYENKEKLSA	LPPEGGKPYL
801	811	821	831	841	851	861	871	881	891
ESFKLSLDNT	KDTLLPDEVS	TLSKKEKIPL	QMEELSTAVY	SNDDLFISKE	AQIRETETFS	DSSPIEIIDE	FPTLISSKTD	SFSKLAREYT	DLEVSHKSEI
901	911	921	931	941	951	961	971	981	991
ANAPDGAGSL	PCTELPHDLS	LKNIQPKVEE	KISFSDDFSK	NGSATSKVLL	LPPDVSALAT	QAEIESIVKP	KVLVKEAEKK	LPSDTEKEDR	SPSAIFSAEL
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
SKTSVVDLLY	WRDIKKTGVV	FGASLFLLLS	LTVFSIVSVT	AYIALALLSV	TISFRIYKGV	IQAIQKSDEG	HPFRAYLESE	VAISEELVQK	YSNSALGHVN
1101	1111	1121	1131	1141	1151	1161	1171	1181	1191
CTIKELRRLF	LVDDLVDSLK	FAVLMWVFTY	VGALFNGLTL	LILALISLFS	VPVIYERHQA	QIDHYLGLAN	KNVKDAMAKI	QAKIPGLKRK	AE

Reference

ID	Publication
1	Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
33	Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.

UniProtKB-Q9NQC3

Glycosites

Sequence

Reference