Detail


Protein	Cadherin EGF LAG seven-pass G-type receptor 3
Gene	CELSR3
Status	Reviewed
Source	Breast cancer xenografts; HCC cell lines (Liver); OVCAR-3 cell line (Ovarian cancer)
Years	2013-2015

Site	Identified Peptides	Year(Publication ID)
1713	nGTMAGCQAK	2015(1);
2053	GFDPNCnK	2015(unpublished);
2196	ELSLLLDGLELnK	2013(40);

Sequence

1	11	21	31	41	51	61	71	81	91
MMARRPPWRG	LGGRSTPILL	LLLLSLFPLS	QEELGGGGHQ	GWDPGLAATT	GPRAHIGGGA	LALCPESSGV	REDGGPGLGV	REPIFVGLRG	RRQSARNSRG
101	111	121	131	141	151	161	171	181	191
PPEQPNEELG	IEHGVQPLGS	RERETGQGPG	SVLYWRPEVS	SCGRTGPLQR	GSLSPGALSS	GVPGSGNSSP	LPSDFLIRHH	GPKPVSSQRN	AGTGSRKRVG
201	211	221	231	241	251	261	271	281	291
TARCCGELWA	TGSKGQGERA	TTSGAERTAP	RRNCLPGASG	SGPELDSAPR	TARTAPASGS	APRESRTAPE	PAPKRMRSRG	LFRCRFLPQR	PGPRPPGLPA
301	311	321	331	341	351	361	371	381	391
RPEARKVTSA	NRARFRRAAN	RHPQFPQYNY	QTLVPENEAA	GTAVLRVVAQ	DPDAGEAGRL	VYSLAALMNS	RSLELFSIDP	QSGLIRTAAA	LDRESMERHY
401	411	421	431	441	451	461	471	481	491
LRVTAQDHGS	PRLSATTMVA	VTVADRNDHS	PVFEQAQYRE	TLRENVEEGY	PILQLRATDG	DAPPNANLRY	RFVGPPAARA	AAAAAFEIDP	RSGLISTSGR
501	511	521	531	541	551	561	571	581	591
VDREHMESYE	LVVEASDQGQ	EPGPRSATVR	VHITVLDEND	NAPQFSEKRY	VAQVREDVRP	HTVVLRVTAT	DRDKDANGLV	HYNIISGNSR	GHFAIDSLTG
601	611	621	631	641	651	661	671	681	691
EIQVVAPLDF	EAEREYALRI	RAQDAGRPPL	SNNTGLASIQ	VVDINDHIPI	FVSTPFQVSV	LENAPLGHSV	IHIQAVDADH	GENARLEYSL	TGVAPDTPFV
701	711	721	731	741	751	761	771	781	791
INSATGWVSV	SGPLDRESVE	HYFFGVEARD	HGSPPLSASA	SVTVTVLDVN	DNRPEFTMKE	YHLRLNEDAA	VGTSVVSVTA	VDRDANSAIS	YQITGGNTRN
801	811	821	831	841	851	861	871	881	891
RFAISTQGGV	GLVTLALPLD	YKQERYFKLV	LTASDRALHD	HCYVHINITD	ANTHRPVFQS	AHYSVSVNED	RPMGSTIVVI	SASDDDVGEN	ARITYLLEDN
901	911	921	931	941	951	961	971	981	991
LPQFRIDADS	GAITLQAPLD	YEDQVTYTLA	ITARDNGIPQ	KADTTYVEVM	VNDVNDNAPQ	FVASHYTGLV	SEDAPPFTSV	LQISATDRDA	HANGRVQYTF
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
QNGEDGDGDF	TIEPTSGIVR	TVRRLDREAV	SVYELTAYAV	DRGVPPLRTP	VSIQVMVQDV	NDNAPVFPAE	EFEVRVKENS	IVGSVVAQIT	AVDPDEGPNA
1101	1111	1121	1131	1141	1151	1161	1171	1181	1191
HIMYQIVEGN	IPELFQMDIF	SGELTALIDL	DYEARQEYVI	VVQATSAPLV	SRATVHVRLV	DQNDNSPVLN	NFQILFNNYV	SNRSDTFPSG	IIGRIPAYDP
1201	1211	1221	1231	1241	1251	1261	1271	1281	1291
DVSDHLFYSF	ERGNELQLLV	VNQTSGELRL	SRKLDNNRPL	VASMLVTVTD	GLHSVTAQCV	LRVVIITEEL	LANSLTVRLE	NMWQERFLSP	LLGRFLEGVA
1301	1311	1321	1331	1341	1351	1361	1371	1381	1391
AVLATPAEDV	FIFNIQNDTD	VGGTVLNVSF	SALAPRGAGA	GAAGPWFSSE	ELQEQLYVRR	AALAARSLLD	VLPFDDNVCL	REPCENYMKC	VSVLRFDSSA
1401	1411	1421	1431	1441	1451	1461	1471	1481	1491
PFLASASTLF	RPIQPIAGLR	CRCPPGFTGD	FCETELDLCY	SNPCRNGGAC	ARREGGYTCV	CRPRFTGEDC	ELDTEAGRCV	PGVCRNGGTC	TDAPNGGFRC
1501	1511	1521	1531	1541	1551	1561	1571	1581	1591
QCPAGGAFEG	PRCEVAARSF	PPSSFVMFRG	LRQRFHLTLS	LSFATVQQSG	LLFYNGRLNE	KHDFLALELV	AGQVRLTYST	GESNTVVSPT	VPGGLSDGQW
1601	1611	1621	1631	1641	1651	1661	1671	1681	1691
HTVHLRYYNK	PRTDALGGAQ	GPSKDKVAVL	SVDDCDVAVA	LQFGAEIGNY	SCAAAGVQTS	SKKSLDLTGP	LLLGGVPNLP	ENFPVSHKDF	IGCMRDLHID
1701	1711	1721	1731	1741	1751	1761	1771	1781	1791
GRRVDMAAFV	ANNGTMAGCQ	AKLHFCDSGP	CKNSGFCSER	WGSFSCDCPV	GFGGKDCQLT	MAHPHHFRGN	GTLSWNFGSD	MAVSVPWYLG	LAFRTRATQG
1801	1811	1821	1831	1841	1851	1861	1871	1881	1891
VLMQVQAGPH	STLLCQLDRG	LLSVTVTRGS	GRASHLLLDQ	VTVSDGRWHD	LRLELQEEPG	GRRGHHVLMV	SLDFSLFQDT	MAVGSELQGL	KVKQLHVGGL
1901	1911	1921	1931	1941	1951	1961	1971	1981	1991
PPGSAEEAPQ	GLVGCIQGVW	LGSTPSGSPA	LLPPSHRVNA	EPGCVVTNAC	ASGPCPPHAD	CRDLWQTFSC	TCQPGYYGPG	CVDACLLNPC	QNQGSCRHLP
2001	2011	2021	2031	2041	2051	2061	2071	2081	2091
GAPHGYTCDC	VGGYFGHHCE	HRMDQQCPRG	WWGSPTCGPC	NCDVHKGFDP	NCNKTNGQCH	CKEFHYRPRG	SDSCLPCDCY	PVGSTSRSCA	PHSGQCPCRP
2101	2111	2121	2131	2141	2151	2161	2171	2181	2191
GALGRQCNSC	DSPFAEVTAS	GCRVLYDACP	KSLRSGVWWP	QTKFGVLATV	PCPRGALGAA	VRLCDEAQGW	LEPDLFNCTS	PAFRELSLLL	DGLELNKTAL
2201	2211	2221	2231	2241	2251	2261	2271	2281	2291
DTMEAKKLAQ	RLREVTGHTD	HYFSQDVRVT	ARLLAHLLAF	ESHQQGFGLT	ATQDAHFNEN	LLWAGSALLA	PETGDLWAAL	GQRAPGGSPG	SAGLVRHLEE
2301	2311	2321	2331	2341	2351	2361	2371	2381	2391
YAATLARNME	LTYLNPMGLV	TPNIMLSIDR	MEHPSSPRGA	RRYPRYHSNL	FRGQDAWDPH	THVLLPSQSP	RPSPSEVLPT	SSSIENSTTS	SVVPPPAPPE
2401	2411	2421	2431	2441	2451	2461	2471	2481	2491
PEPGISIIIL	LVYRTLGGLL	PAQFQAERRG	ARLPQNPVMN	SPVVSVAVFH	GRNFLRGILE	SPISLEFRLL	QTANRSKAIC	VQWDPPGLAE	QHGVWTARDC
2501	2511	2521	2531	2541	2551	2561	2571	2581	2591
ELVHRNGSHA	RCRCSRTGTF	GVLMDASPRE	RLEGDLELLA	VFTHVVVAVS	VAALVLTAAI	LLSLRSLKSN	VRGIHANVAA	ALGVAELLFL	LGIHRTHNQL
2601	2611	2621	2631	2641	2651	2661	2671	2681	2691
VCTAVAILLH	YFFLSTFAWL	FVQGLHLYRM	QVEPRNVDRG	AMRFYHALGW	GVPAVLLGLA	VGLDPEGYGN	PDFCWISVHE	PLIWSFAGPV	VLVIVMNGTM
2701	2711	2721	2731	2741	2751	2761	2771	2781	2791
FLLAARTSCS	TGQREAKKTS	ALTLRSSFLL	LLLVSASWLF	GLLAVNHSIL	AFHYLHAGLC	GLQGLAVLLL	FCVLNADARA	AWMPACLGRK	AAPEEARPAP
2801	2811	2821	2831	2841	2851	2861	2871	2881	2891
GLGPGAYNNT	ALFEESGLIR	ITLGASTVSS	VSSARSGRTQ	DQDSQRGRSY	LRDNVLVRHG	SAADHTDHSL	QAHAGPTDLD	VAMFHRDAGA	DSDSDSDLSL
2901	2911	2921	2931	2941	2951	2961	2971	2981	2991
EEERSLSIPS	SESEDNGRTR	GRFQRPLCRA	AQSERLLTHP	KDVDGNDLLS	YWPALGECEA	APCALQTWGS	ERRLGLDTSK	DAANNNQPDP	ALTSGDETSL
3001	3011	3021	3031	3041	3051	3061	3071	3081	3091
GRAQRQRKGI	LKNRLQYPLV	PQTRGAPELS	WCRAATLGHR	AVPAASYGRI	YAGGGTGSLS	QPASRYSSRE	QLDLLLRRQL	SRERLEEAPA	PVLRPLSRPG
3101	3111	3121	3131	3141	3151	3161	3171	3181	3191
SQECMDAAPG	RLEPKDRGST	LPRRQPPRDY	PGAMAGRFGS	RDALDLGAPR	EWLSTLPPPR	RTRDLDPQPP	PLPLSPQRQL	SRDPLLPSRP	LDSLSRSSNS
3201	3211	3221	3231	3241	3251	3261	3271	3281	3291
REQLDQVPSR	HPSREALGPL	PQLLRAREDS	VSGPSHGPST	EQLDILSSIL	ASFNSSALSS	VQSSSTPLGP	HTTATPSATA	SVLGPSTPRS	ATSHSISELS
3301	3311
PDSEVPRSEG	HS

UniProtKB-Q9NYQ7

Glycosites

Sequence

Reference

ID	Publication
1	Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
40	Li X, Jiang J, Zhao X, Wang J, Han H, Zhao Y, Peng B, Zhong R, Ying W, Qian X: N-glycoproteome Analysis of the Secretome of Human Metastatic Hepatocellular Carcinoma Cell Lines Combining Hydrazide Chemistry, HILIC Enrichment and Mass Spectrometry. Plos One 2013, 8.