Detail


Protein	Sacsin
Gene	SACS
Status	Reviewed
Source	Liver; OVCAR-3 cell line (Ovarian cancer)
Years	2014-2015

Site	Identified Peptides	Year(Publication ID)
1537	VnLTRL	2014(33);
3757	nITTLDEEMVKTR	2015(1);

Sequence

1	11	21	31	41	51	61	71	81	91
METKENRWVP	VTVLPGCVGC	RTVAALASWT	VRDVKERIFA	ETGFPVSEQR	LWRGGRELSD	WIKIGDLTSK	NCHLFVNLQS	KGLKGGGRFG	QTTPPLVDFL
101	111	121	131	141	151	161	171	181	191
KDILRRYPEG	GQILKELIQN	AEDAGATEVK	FLYDETQYGT	ETLWSKDMAP	YQGPALYVYN	NAVFTPEDWH	GIQEIARSRK	KDDPLKVGRF	GIGFNSVYHI
201	211	221	231	241	251	261	271	281	291
TDVPCIFSGD	QIGMLDPHQT	LFGPHESGQC	WNLKDDSKEI	SELSDQFAPF	VGIFGSTKET	FINGNFPGTF	FRFPLRLQPS	QLSSNLYNKQ	KVLELFESFR
301	311	321	331	341	351	361	371	381	391
ADADTVLLFL	KSVQDVSLYV	READGTEKLV	FRVTSSESKA	LKHERPNSIK	ILGTAISNYC	KKTPSNNITC	VTYHVNIVLE	EESTKDAQKT	SWLVCNSVGG
401	411	421	431	441	451	461	471	481	491
RGISSKLDSL	ADELKFVPII	GIAMPLSSRD	DEAKGATSDF	SGKAFCFLPL	PPGEESSTGL	PVHISGFFGL	TDNRRSIKWR	ELDQWRDPAA	LWNEFLVMNV
501	511	521	531	541	551	561	571	581	591
VPKAYATLIL	DSIKRLEMEK	SSDFPLSVDV	IYKLWPEASK	VKVHWQPVLE	PLFSELLQNA	VIYSISCDWV	RLEQVYFSEL	DENLEYTKTV	LNYLQSSGKQ
601	611	621	631	641	651	661	671	681	691
IAKVPGNVDA	AVQLTAASGT	TPVRKVTPAW	VRQVLRKCAH	LGCAEEKLHL	LEFVLSDQAY	SELLGLELLP	LQNGNFVPFS	SSVSDQDVIY	ITSAEYPRSL
701	711	721	731	741	751	761	771	781	791
FPSLEGRFIL	DNLKPHLVAA	LKEAAQTRGR	PCTQLQLLNP	ERFARLIKEV	MNTFWPGREL	IVQWYPFDEN	RNHPSVSWLK	MVWKNLYIHF	SEDLTLFDEM
801	811	821	831	841	851	861	871	881	891
PLIPRTILEE	GQTCVELIRL	RIPSLVILDD	ESEAQLPEFL	ADIVQKLGGF	VLKKLDASIQ	HPLIKKYIHS	PLPSAVLQIM	EKMPLQKLCN	QITSLLPTHK
901	911	921	931	941	951	961	971	981	991
DALRKFLASL	TDSSEKEKRI	IQELAIFKRI	NHSSDQGISS	YTKLKGCKVL	HHTAKLPADL	RLSISVIDSS	DEATIRLANM	LKIEQLKTTS	CLKLVLKDIE
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
NAFYSHEEVT	QLMLWVLENL	SSLKNENPNV	LEWLTPLKFI	QISQEQMVSA	GELFDPDIEV	LKDLFCNEEG	TYFPPSVFTS	PDILHSLRQI	GLKNEASLKE
1101	1111	1121	1131	1141	1151	1161	1171	1181	1191
KDVVQVAKKI	EALQVGACPD	QDVLLKKAKT	LLLVLNKNHT	LLQSSEGKMT	LKKIKWVPAC	KERPPNYPGS	LVWKGDLCNL	CAPPDMCDVG	HAILIGSSLP
1201	1211	1221	1231	1241	1251	1261	1271	1281	1291
LVESIHVNLE	KALGIFTKPS	LSAVLKHFKI	VVDWYSSKTF	SDEDYYQFQH	ILLEIYGFMH	DHLNEGKDSF	RALKFPWVWT	GKKFCPLAQA	VIKPIHDLDL
1301	1311	1321	1331	1341	1351	1361	1371	1381	1391
QPYLHNVPKT	MAKFHQLFKV	CGSIEELTSD	HISMVIQKIY	LKSDQDLSEQ	ESKQNLHLML	NIIRWLYSNQ	IPASPNTPVP	IHHSKNPSKL	IMKPIHECCY
1401	1411	1421	1431	1441	1451	1461	1471	1481	1491
CDIKVDDLND	LLEDSVEPII	LVHEDIPMKT	AEWLKVPCLS	TRLINPENMG	FEQSGQREPL	TVRIKNILEE	YPSVSDIFKE	LLQNADDANA	TECSFLIDMR
1501	1511	1521	1531	1541	1551	1561	1571	1581	1591
RNMDIRENLL	DPGMAACHGP	ALWSFNNSQF	SDSDFVNITR	LGESLKRGEV	DKVGKFGLGF	NSVYHITDIP	IIMSREFMIM	FDPNINHISK	HIKDKSNPGI
1601	1611	1621	1631	1641	1651	1661	1671	1681	1691
KINWSKQQKR	LRKFPNQFKP	FIDVFGCQLP	LTVEAPYSYN	GTLFRLSFRT	QQEAKVSEVS	STCYNTADIY	SLVDEFSLCG	HRLIIFTQSV	KSMYLKYLKI
1701	1711	1721	1731	1741	1751	1761	1771	1781	1791
EETNPSLAQD	TVIIKKKSCS	SKALNTPVLS	VLKEAAKLMK	TCSSSNKKLP	SDEPKSSCIL	QITVEEFHHV	FRRIADLQSP	LFRGPDDDPA	ALFEMAKSGQ
1801	1811	1821	1831	1841	1851	1861	1871	1881	1891
SKKPSDELSQ	KTVECTTWLL	CTCMDTGEAL	KFSLSESGRR	LGLVPCGAVG	VQLSEIQDQK	WTVKPHIGEV	FCYLPLRIKT	GLPVHINGCF	AVTSNRKEIW
1901	1911	1921	1931	1941	1951	1961	1971	1981	1991
KTDTKGRWNT	TFMRHVIVKA	YLQVLSVLRD	LATSGELMDY	TYYAVWPDPD	LVHDDFSVIC	QGFYEDIAHG	KGKELTKVFS	DGSTWVSMKN	VRFLDDSILK
2001	2011	2021	2031	2041	2051	2061	2071	2081	2091
RRDVGSAAFK	IFLKYLKKTG	SKNLCAVELP	SSVKLGFEEA	GCKQILLENT	FSEKQFFSEV	FFPNIQEIEA	ELRDPLMIFV	LNEKVDEFSG	VLRVTPCIPC
2101	2111	2121	2131	2141	2151	2161	2171	2181	2191
SLEGHPLVLP	SRLIHPEGRV	AKLFDIKDGR	FPYGSTQDYL	NPIILIKLVQ	LGMAKDDILW	DDMLERAVSV	AEINKSDHVA	ACLRSSILLS	LIDEKLKIRD
2201	2211	2221	2231	2241	2251	2261	2271	2281	2291
PRAKDFAAKY	QTIRFLPFLT	KPAGFSLDWK	GNSFKPETMF	AATDLYTAEH	QDIVCLLQPI	LNENSHSFRG	CGSVSLAVKE	FLGLLKKPTV	DLVINQLKEV
2301	2311	2321	2331	2341	2351	2361	2371	2381	2391
AKSVDDGITL	YQENITNACY	KYLHEALMQN	EITKMSIIDK	LKPFSFILVE	NAYVDSEKVS	FHLNFEAAPY	LYQLPNKYKN	NFRELFETVG	VRQSCTVEDF
2401	2411	2421	2431	2441	2451	2461	2471	2481	2491
ALVLESIDQE	RGTKQITEEN	FQLCRRIISE	GIWSLIREKK	QEFCEKNYGK	ILLPDTNLML	LPAKSLCYND	CPWIKVKDTT	VKYCHADIPR	EVAVKLGAVP
2501	2511	2521	2531	2541	2551	2561	2571	2581	2591
KRHKALERYA	SNVCFTTLGT	EFGQKEKLTS	RIKSILNAYP	SEKEMLKELL	QNADDAKATE	ICFVFDPRQH	PVDRIFDDKW	APLQGPALCV	YNNQPFTEDD
2601	2611	2621	2631	2641	2651	2661	2671	2681	2691
VRGIQNLGKG	TKEGNPYKTG	QYGIGFNSVY	HITDCPSFIS	GNDILCIFDP	HARYAPGATS	ISPGRMFRDL	DADFRTQFSD	VLDLYLGTHF	KLDNCTMFRF
2701	2711	2721	2731	2741	2751	2761	2771	2781	2791
PLRNAEMAKV	SEISSVPASD	RMVQNLLDKL	RSDGAELLMF	LNHMEKISIC	EIDKSTGALN	VLYSVKGKIT	DGDRLKRKQF	HASVIDSVTK	KRQLKDIPVQ
2801	2811	2821	2831	2841	2851	2861	2871	2881	2891
QITYTMDTED	SEGNLTTWLI	CNRSGFSSME	KVSKSVISAH	KNQDITLFPR	GGVAACITHN	YKKPHRAFCF	LPLSLETGLP	FHVNGHFALD	SARRNLWRDD
2901	2911	2921	2931	2941	2951	2961	2971	2981	2991
NGVGVRSDWN	NSLMTALIAP	AYVELLIQLK	KRYFPGSDPT	LSVLQNTPIH	VVKDTLKKFL	SFFPVNRLDL	QPDLYCLVKA	LYNCIHEDMK	RLLPVVRAPN
3001	3011	3021	3031	3041	3051	3061	3071	3081	3091
IDGSDLHSAV	IITWINMSTS	NKTRPFFDNL	LQDELQHLKN	ADYNITTRKT	VAENVYRLKH	LLLEIGFNLV	YNCDETANLY	HCLIDADIPV	SYVTPADIRS
3101	3111	3121	3131	3141	3151	3161	3171	3181	3191
FLMTFSSPDT	NCHIGKLPCR	LQQTNLKLFH	SLKLLVDYCF	KDAEENEIEV	EGLPLLITLD	SVLQTFDAKR	PKFLTTYHEL	IPSRKDLFMN	TLYLKYSNIL
3201	3211	3221	3231	3241	3251	3261	3271	3281	3291
LNCKVAKVFD	ISSFADLLSS	VLPREYKTKS	CTKWKDNFAS	ESWLKNAWHF	ISESVSVKED	QEETKPTFDI	VVDTLKDWAL	LPGTKFTVSA	NQLVVPEGDV
3301	3311	3321	3331	3341	3351	3361	3371	3381	3391
LLPLSLMHIA	VFPNAQSDKV	FHALMKAGCI	QLALNKICSK	DSAFVPLLSC	HTANIESPTS	ILKALHYMVQ	TSTFRAEKLV	ENDFEALLMY	FNCNLNHLMS
3401	3411	3421	3431	3441	3451	3461	3471	3481	3491
QDDIKILKSL	PCYKSISGRY	VSIGKFGTCY	VLTKSIPSAE	VEKWTQSSSS	AFLEEKIHLK	ELYEVIGCVP	VDDLEVYLKH	LLPKIENLSY	DAKLEHLIYL
3501	3511	3521	3531	3541	3551	3561	3571	3581	3591
KNRLSSAEEL	SEIKEQLFEK	LESLLIIHDA	NSRLKQAKHF	YDRTVRVFEV	MLPEKLFIPN	DFFKKLEQLI	KPKNHVTFMT	SWVEFLRNIG	LKYILSQQQL
3601	3611	3621	3631	3641	3651	3661	3671	3681	3691
LQFAKEISVR	ANTENWSKET	LQNTVDILLH	HIFQERMDLL	SGNFLKELSL	IPFLCPERAP	AEFIRFHPQY	QEVNGTLPLI	KFNGAQVNPK	FKQCDVLQLL
3701	3711	3721	3731	3741	3751	3761	3771	3781	3791
WTSCPILPEK	ATPLSIKEQE	GSDLGPQEQL	EQVLNMLNVN	LDPPLDKVIN	NCRNICNITT	LDEEMVKTRA	KVLRSIYEFL	SAEKREFRFQ	LRGVAFVMVE
3801	3811	3821	3831	3841	3851	3861	3871	3881	3891
DGWKLLKPEE	VVINLEYESD	FKPYLYKLPL	ELGTFHQLFK	HLGTEDIIST	KQYVEVLSRI	FKNSEGKQLD	PNEMRTVKRV	VSGLFRSLQN	DSVKVRSDLE
3901	3911	3921	3931	3941	3951	3961	3971	3981	3991
NVRDLALYLP	SQDGRLVKSS	ILVFDDAPHY	KSRIQGNIGV	QMLVDLSQCY	LGKDHGFHTK	LIMLFPQKLR	PRLLSSILEE	QLDEETPKVC	QFGALCSLQG
4001	4011	4021	4031	4041	4051	4061	4071	4081	4091
RLQLLLSSEQ	FITGLIRIMK	HENDNAFLAN	EEKAIRLCKA	LREGLKVSCF	EKLQTTLRVK	GFNPIPHSRS	ETFAFLKRFG	NAVILLYIQH	SDSKDINFLL
4101	4111	4121	4131	4141	4151	4161	4171	4181	4191
ALAMTLKSAT	DNLISDTSYL	IAMLGCNDIY	RIGEKLDSLG	VKYDSSEPSK	LELPMPGTPI	PAEIHYTLLM	DPMNVFYPGE	YVGYLVDAEG	GDIYGSYQPT
4201	4211	4221	4231	4241	4251	4261	4271	4281	4291
YTYAIIVQEV	EREDADNSSF	LGKIYQIDIG	YSEYKIVSSL	DLYKFSRPEE	SSQSRDSAPS	TPTSPTEFLT	PGLRSIPPLF	SGRESHKTSS	KHQSPKKLKV
4301	4311	4321	4331	4341	4351	4361	4371	4381	4391
NSLPEILKEV	TSVVEQAWKL	PESERKKIIR	RLYLKWHPDK	NPENHDIANE	VFKHLQNEIN	RLEKQAFLDQ	NADRASRRTF	STSASRFQSD	KYSFQRFYTS
4401	4411	4421	4431	4441	4451	4461	4471	4481	4491
WNQEATSHKS	ERQQQNKEKC	PPSAGQTYSQ	RFFVPPTFKS	VGNPVEARRW	LRQARANFSA	ARNDLHKNAN	EWVCFKCYLS	TKLALIAADY	AVRGKSDKDV
4501	4511	4521	4531	4541	4551	4561	4571
KPTALAQKIE	EYSQQLEGLT	NDVHTLEAYG	VDSLKTRYPD	LLPFPQIPND	RFTSEVAMRV	MECTACIIIK	LENFMQQKV

UniProtKB-Q9NZJ4

Glycosites

Sequence

Reference

ID	Publication
1	Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
33	Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.