Detail

Contains

UniProtKB-Q9P2K2


Protein	Thioredoxin domain-containing protein 16
Gene	TXNDC16
Status	Reviewed
Source	Breast cancer xenografts; DLBCL cell lines (Diffuse large B-cell lymphoma); HEK293 cell line (embryonic kidney); Hela cell line (cervical cancer); LNCap/PC3 cell lines (Prostate cancer); Liver; Non-small Cell Lung Carcinoma; Ovarian tumor
Years	2014-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
460	QnVTEFPIIK	2014(15); 2014(16); 2014(33); 2015(2); 2015(unpublished);2015(12);
460	INCADWSDVCTKQnVTEFPIIK	2014(18);
502	ISYPVnITSIQEAEEYLSGELYK	2014(33); 2015(unpublished);2015(2);

Sequence

1	11	21	31	41	51	61	71	81	91
MFSGFNVFRV	GISFVIMCIF	YMPTVNSLPE	LSPQKYFSTL	QPGKASLAYF	CQADSPRTSV	FLEELNEAVR	PLQDYGISVA	KVNCVKEEIS	RYCGKEKDLM
101	111	121	131	141	151	161	171	181	191
KAYLFKGNIL	LREFPTDTLF	DVNAIVAHVL	FALLFSEVKY	ITNLEDLQNI	ENALKGKANI	IFSYVRAIGI	PEHRAVMEAA	FVYGTTYQFV	LTTEIALLES
201	211	221	231	241	251	261	271	281	291
IGSEDVEYAH	LYFFHCKLVL	DLTQQCRRTL	MEQPLTTLNI	HLFIKTMKAP	LLTEVAEDPQ	QVSTVHLQLG	LPLVFIVSQQ	ATYEADRRTA	EWVAWRLLGK
301	311	321	331	341	351	361	371	381	391
AGVLLLLRDS	LEVNIPQDAN	VVFKRAEEGV	PVEFLVLHDV	DLIISHVENN	MHIEEIQEDE	DNDMEGPDID	VQDDEVAETV	FRDRKRKLPL	ELTVELTEET
401	411	421	431	441	451	461	471	481	491
FNATVMASDS	IVLFYAGWQA	VSMAFLQSYI	DVAVKLKGTS	TMLLTRINCA	DWSDVCTKQN	VTEFPIIKMY	KKGENPVSYA	GMLGTEDLLK	FIQLNRISYP
501	511	521	531	541	551	561	571	581	591
VNITSIQEAE	EYLSGELYKD	LILYSSVSVL	GLFSPTMKTA	KEDFSEAGNY	LKGYVITGIY	SEEDVLLLST	KYAASLPALL	LARHTEGKIE	SIPLASTHAQ
601	611	621	631	641	651	661	671	681	691
DIVQIITDAL	LEMFPEITVE	NLPSYFRLQK	PLLILFSDGT	VNPQYKKAIL	TLVKQKYLDS	FTPCWLNLKN	TPVGRGILRA	YFDPLPPLPL	LVLVNLHSGG
701	711	721	731	741	751	761	771	781	791
QVFAFPSDQA	IIEENLVLWL	KKLEAGLENH	ITILPAQEWK	PPLPAYDFLS	MIDAATSQRG	TRKVPKCMKE	TDVQENDKEQ	HEDKSAVRKE	PIETLRIKHW
801	811	821
NRSNWFKEAE	KSFRRDKELG	CSKVN

Reference

ID	Publication
2	Shah P, Wang X, Yang W, Eshghi ST, Sun S, Hoti N, Chen L, Yang S, Pasay J, Rubin A: Integrated Proteomic and Glycoproteomic Analyses of Prostate Cancer Cells Reveal Glycoprotein Alteration in Protein Abundance and Glycosylation. Molecular & Cellular Proteomics 2015, 14:2753-2763.
12	Weng Y, Sui Z, Jiang H, Shan Y, Chen L, Zhang S, Zhang L, Zhang Y: Releasing N-glycan from Peptide N-terminus by N-terminal Succinylation Assisted Enzymatic Deglycosylation. Scientific Reports 2015, 5.
15	Chen R, Seebun D, Ye M, Zou H, Figeys D: Site-specific characterization of cell membrane N-glycosylation with integrated hydrophilic interaction chromatography solid phase extraction and LC-MS/MS. Journal of Proteomics 2014, 103:194-203.
16	Deeb SJ, Cox J, Schmidt-Supprian M, Mann M: N-linked Glycosylation Enrichment for In-depth Cell Surface Proteomics of Diffuse Large B-cell Lymphoma Subtypes. Molecular & Cellular Proteomics 2014, 13:240-251.
18	Hirao Y, Matsuzaki H, Iwaki J, Kuno A, Kaji H, Ohkura T, Togayachi A, Abe M, Nomura M, Noguchi M, et al: Glycoproteomics Approach for Identifying Glycobiomarker Candidate Molecules for Tissue Type Classification of Non-small Cell Lung Carcinoma. Journal of Proteome Research 2014, 13:4705-4716.
33	Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.