Detail


Protein	Tight junction protein ZO-2
Gene	TJP2
Status	Reviewed
Source	Liver; OVCAR-3 cell line (Ovarian cancer)
Years	2014-2015

Site	Identified Peptides	Year(Publication ID)
396	DSQQTLINIPSLnDSDSEIEDISEIESNR	2014(33);
411	DSQQTLINIPSLNDSDSEIEDISEIESnR	2014(33);
1025	nETPGASTK	2015(1);

Sequence

1	11	21	31	41	51	61	71	81	91
MPVRGDRGFP	PRRELSGWLR	APGMEELIWE	QYTVTLQKDS	KRGFGIAVSG	GRDNPHFENG	ETSIVISDVL	PGGPADGLLQ	ENDRVVMVNG	TPMEDVLHSF
101	111	121	131	141	151	161	171	181	191
AVQQLRKSGK	VAAIVVKRPR	KVQVAALQAS	PPLDQDDRAF	EVMDEFDGRS	FRSGYSERSR	LNSHGGRSRS	WEDSPERGRP	HERARSRERD	LSRDRSRGRS
201	211	221	231	241	251	261	271	281	291
LERGLDQDHA	RTRDRSRGRS	LERGLDHDFG	PSRDRDRDRS	RGRSIDQDYE	RAYHRAYDPD	YERAYSPEYR	RGARHDARSR	GPRSRSREHP	HSRSPSPEPR
301	311	321	331	341	351	361	371	381	391
GRPGPIGVLL	MKSRANEEYG	LRLGSQIFVK	EMTRTGLATK	DGNLHEGDII	LKINGTVTEN	MSLTDARKLI	EKSRGKLQLV	VLRDSQQTLI	NIPSLNDSDS
401	411	421	431	441	451	461	471	481	491
EIEDISEIES	NRSFSPEERR	HQYSDYDYHS	SSEKLKERPS	SREDTPSRLS	RMGATPTPFK	STGDIAGTVV	PETNKEPRYQ	EDPPAPQPKA	APRTFLRPSP
501	511	521	531	541	551	561	571	581	591
EDEAIYGPNT	KMVRFKKGDS	VGLRLAGGND	VGIFVAGIQE	GTSAEQEGLQ	EGDQILKVNT	QDFRGLVRED	AVLYLLEIPK	GEMVTILAQS	RADVYRDILA
601	611	621	631	641	651	661	671	681	691
CGRGDSFFIR	SHFECEKETP	QSLAFTRGEV	FRVVDTLYDG	KLGNWLAVRI	GNELEKGLIP	NKSRAEQMAS	VQNAQRDNAG	DRADFWRMRG	QRSGVKKNLR
701	711	721	731	741	751	761	771	781	791
KSREDLTAVV	SVSTKFPAYE	RVLLREAGFK	RPVVLFGPIA	DIAMEKLANE	LPDWFQTAKT	EPKDAGSEKS	TGVVRLNTVR	QIIEQDKHAL	LDVTPKAVDL
801	811	821	831	841	851	861	871	881	891
LNYTQWFPIV	IFFNPDSRQG	VKTMRQRLNP	TSNKSSRKLF	DQANKLKKTC	AHLFTATINL	NSANDSWFGS	LKDTIQHQQG	EAVWVSEGKM	EGMDDDPEDR
901	911	921	931	941	951	961	971	981	991
MSYLTAMGAD	YLSCDSRLIS	DFEDTDGEGG	AYTDNELDEP	AEEPLVSSIT	RSSEPVQHEE	SIRKPSPEPR	AQMRRAASSD	QLRDNSPPPA	FKPEPPKAKT
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
QNKEESYDFS	KSYEYKSNPS	AVAGNETPGA	STKGYPPPVA	AKPTFGRSIL	KPSTPIPPQE	GEEVGESSEE	QDNAPKSVLG	KVKIFEKMDH	KARLQRMQEL
1101	1111	1121	1131	1141	1151	1161	1171	1181
QEAQNARIEI	AQKHPDIYAV	PIKTHKPDPG	TPQHTSSRPP	EPQKAPSRPY	QDTRGSYGSD	AEEEEYRQQL	SEHSKRGYYG	QSARYRDTEL

Reference

ID	Publication
1	Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
33	Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.

UniProtKB-Q9UDY2

Glycosites

Sequence

Reference