Detail

UniProtKB-Q9ULB1


Protein	Neurexin-1
Gene	NRXN1
Status	Reviewed
Source	22Rv1 cell line (prostate cancer); Cerebrospinal fluid; Colorectal tumor; Pancreatic islets; Prostate tumor; Serum; Urine
Years	2007-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
125	nTTLFIDQVEAK	2015(unpublished);2015(unpublished);2007(unpublished);2007;2007;
190	VnSSQVLPVDSGEVK	2007(48); 2012(50); 2012(22); 2014(unpublished);2015(unpublished);2015(unpublished);2015;2007;2007;2007;
190	DVRVnSSQVLPVDSGEVK	2015(unpublished);2015(unpublished);

Sequence

1	11	21	31	41	51	61	71	81	91
MGTALLQRGG	CFLLCLSLLL	LGCWAELGSG	LEFPGAEGQW	TRFPKWNACC	ESEMSFQLKT	RSARGLVLYF	DDEGFCDFLE	LILTRGGRLQ	LSFSIFCAEP
101	111	121	131	141	151	161	171	181	191
ATLLADTPVN	DGAWHSVRIR	RQFRNTTLFI	DQVEAKWVEV	KSKRRDMTVF	SGLFVGGLPP	ELRAAALKLT	LASVREREPF	KGWIRDVRVN	SSQVLPVDSG
201	211	221	231	241	251	261	271	281	291
EVKLDDEPPN	SGGGSPCEAG	EEGEGGVCLN	GGVCSVVDDQ	AVCDCSRTGF	RGKDCSQEDN	NVEGLAHLMM	GDQGKSKGKE	EYIATFKGSE	YFCYDLSQNP
301	311	321	331	341	351	361	371	381	391
IQSSSDEITL	SFKTLQRNGL	MLHTGKSADY	VNLALKNGAV	SLVINLGSGA	FEALVEPVNG	KFNDNAWHDV	KVTRNLRQHS	GIGHAMVTIS	VDGILTTTGY
401	411	421	431	441	451	461	471	481	491
TQEDYTMLGS	DDFFYVGGSP	STADLPGSPV	SNNFMGCLKE	VVYKNNDVRL	ELSRLAKQGD	PKMKIHGVVA	FKCENVATLD	PITFETPESF	ISLPKWNAKK
501	511	521	531	541	551	561	571	581	591
TGSISFDFRT	TEPNGLILFS	HGKPRHQKDA	KHPQMIKVDF	FAIEMLDGHL	YLLLDMGSGT	IKIKALLKKV	NDGEWYHVDF	QRDGRSGTIS	VNTLRTPYTA
601	611	621	631	641	651	661	671	681	691
PGESEILDLD	DELYLGGLPE	NKAGLVFPTE	VWTALLNYGY	VGCIRDLFID	GQSKDIRQMA	EVQSTAGVKP	SCSKETAKPC	LSNPCKNNGM	CRDGWNRYVC
701	711	721	731	741	751	761	771	781	791
DCSGTGYLGR	SCEREATVLS	YDGSMFMKIQ	LPVVMHTEAE	DVSLRFRSQR	AYGILMATTS	RDSADTLRLE	LDAGRVKLTV	NLDCIRINCN	SSKGPETLFA
801	811	821	831	841	851	861	871	881	891
GYNLNDNEWH	TVRVVRRGKS	LKLTVDDQQA	MTGQMAGDHT	RLEFHNIETG	IITERRYLSS	VPSNFIGHLQ	SLTFNGMAYI	DLCKNGDIDY	CELNARFGFR
901	911	921	931	941	951	961	971	981	991
NIIADPVTFK	TKSSYVALAT	LQAYTSMHLF	FQFKTTSLDG	LILYNSGDGN	DFIVVELVKG	YLHYVFDLGN	GANLIKGSSN	KPLNDNQWHN	VMISRDTSNL
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
HTVKIDTKIT	TQITAGARNL	DLKSDLYIGG	VAKETYKSLP	KLVHAKEGFQ	GCLASVDLNG	RLPDLISDAL	FCNGQIERGC	EGPSTTCQED	SCSNQGVCLQ
1101	1111	1121	1131	1141	1151	1161	1171	1181	1191
QWDGFSCDCS	MTSFSGPLCN	DPGTTYIFSK	GGGQITYKWP	PNDRPSTRAD	RLAIGFSTVQ	KEAVLVRVDS	SSGLGDYLEL	HIHQGKIGVK	FNVGTDDIAI
1201	1211	1221	1231	1241	1251	1261	1271	1281	1291
EESNAIINDG	KYHVVRFTRS	GGNATLQVDS	WPVIERYPAG	RQLTIFNSQA	TIIIGGKEQG	QPFQGQLSGL	YYNGLKVLNM	AAENDANIAI	VGNVRLVGEV
1301	1311	1321	1331	1341	1351	1361	1371	1381	1391
PSSMTTESTA	TAMQSEMSTS	IMETTTTLAT	STARRGKPPT	KEPISQTTDD	ILVASAECPS	DDEDIDPCEP	SSGGLANPTR	AGGREPYPGS	AEVIRESSST
1401	1411	1421	1431	1441	1451	1461	1471
TGMVVGIVAA	AALCILILLY	AMYKYRNRDE	GSYHVDESRN	YISNSAQSNG	AVVKEKQPSS	AKSSNKNKKN	KDKEYYV

Reference

ID	Publication
22	Nicastri A, Gaspari M, Sacco R, Elia L, Gabriele C, Romano R, Rizzuto A, Cuda G: N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue. Journal of Proteome Research 2014, 13:4932-4941.
48	Danzer C, Eckhardt K, Schmidt A, Fankhauser N, Ribrioux S, Wollscheid B, Mueller L, Schiess R, Zuellig R, Lehmann R, et al: Comprehensive Description of the N-Glycoproteome of Mouse Pancreatic beta-Cells and Human Islets. Journal of Proteome Research 2012, 11:1598-1608.
50	Whitmore TE, Peterson A, Holzman T, Eastham A, Amon L, McIntosh M, Ozinsky A, Nelson PS, Martin DB: Integrative Analysis of N-Linked Human Glycoproteomic Data Sets Reveals PTPRF Ectodomain as a Novel Plasma Biomarker Candidate for Prostate Cancer. Journal of Proteome Research 2012, 11:2653-2665.