Contains      

UniProtKB-Q9Y6C2

Protein EMILIN-1
Gene EMILIN1
Status Reviewed
Source Bladder tumor; Breast tumor; Colorectal tumor; DRO-1 Cell Line (Thyroid Cance); Liver; Liver tumor (HCC); Ovarian tumor; Pancreatic islets; Plasma; Platelet; Platelet Plasma membranes; Prostate; Prostate cancer metastasis to liver; Prostate stromal cell line; Prostate tumor; Serum; Urine; ovarian tumor
Years 2007-20072007

Glycosites

Site Identified Peptides Year(Publication ID)
415 LEDRFnST 2007(unpublished);
415 EDRFnSTLGPSE 2009(64);
415 FnSTLGPSEEQEE 2011(54); 2014(33);
415 LEDRFnSTLGPSEE 2014(33);
415 LEDRFnSTLGPSEEQEE 2014(33);
415 FnSTLGPSEEQEESWPGAPGGLSH 2014(33); 2015(unpublished);
415 LEDRFnSTLGPSEEQEESWPGAPGGL 2014(33);
415 LEDRFnSTLGPSEEQEESWPGAPGGLSH 2014(33); 2015(unpublished);
415 FnSTLGPSEEQEESWPGAPGGLSHWLPAAR 2009(64); 2014(33); 2015(unpublished);
415 IEDRFnSTIGPSEEQEESWPGAPGGISHWIPAAR 2014(32); 2014(32);
415 LEDRFnSTLGPSEEQEESWPGAPGGLSHWLPAAR 2009(64); 2013(34); 2014(33); 2015(unpublished);2015(unpublished);
455 LAnVSGELGGRL 2009(64);
455 GGLLAnVSGELGGR 2014(33);
455 LEQLGGLLAnVSGE 2014(33);
455 GRLEQLGGLLAnVSGE 2014(33);
455 IEQIGGIIAnVSGEIGGR 2014(32); 2014(32);
455 LEQLGGLLAnVSGELGGR 2009(64); 2014(14); 2014(33); 2015(unpublished);2015;2015;2015;2015;2007;
455 GRLEQLGGLLAnVSGELGGR 2009(64); 2013(34); 2014(33); 2015(unpublished);2015(unpublished);
561 LnITAAR 2011(54); 2014(14);
561 LnLTAAR 2011(54); 2014(22); 2014(33); 2015(unpublished);2015(unpublished);2015;2015;2015;2007;2007;
561 TLRLnLTAAR 2014(33);
561 FTLRLnLTAAR 2014(33);
658 FSSLnDSLNE 2014(33);
658 VILSFSSLnDSLNE 2014(33);
658 SSLnDSLNELQTTVEGQGADLADLGATK 2014(33); 2015(unpublished);
766 LRETnTTSQ 2009(64);
766 TnTTSQMQAALLEK 2014(33);
766 ETnTTSQMQAAIIEK 2014(32); 2014(32);
766 ETnTTSQMQAALLEK 2007(74); 2009(62); 2009(64); 2009(65); 2011(54); 2011(55); 2012(48); 2013(34); 2014(13); 2014(14); 2014(22); 2014(33); 2015(unpublished);2015(unpublished);2015(unpublished);2007;2007;2007;
766 HVAGLWAGLRETnTTSQMQAALLEK 2014(33); 2015(unpublished);
766 HVAGLWAGLRETnTTSQMQAALLEKLVGGQAGLGR 2014(33);
794 LGALnSSLQ 2014(33);
794 LGALnSSLQLLE 2014(33);
794 RLGALnSSLQLL 2014(33);
794 RLGALnSSLQLLE 2014(33);
794 LGALnSSLQLLEDR 2007(74); 2009(62); 2009(64); 2009(65); 2011(54); 2012(48); 2013(34); 2014(14); 2014(22); 2014(33); 2015(unpublished);2015(unpublished);2015(unpublished);2007(UnpublishedUnpublished ); 2007;2007;20072007 ;
794 RIGAInSSIQIIEDR 2014(32); 2014(32);
794 RLGALnSSLQLLEDR 2009(64); 2013(34); 2014(33); 2015(unpublished);2015(unpublished);
794 LGALnSSLQLLEDRLHQLSLK 2014(33); 2015(unpublished);
794 RLGALnSSLQLLEDRLHQLSLK 2014(33); 2015(unpublished);

Sequence

1112131415161718191
MAPRTLWSCYLCCLLTAAAGAASYPPRGFSLYTGSSGALSPGGPQAQIAPRPASRHRNWCAYVVTRTVSCVLEDGVETYVKYQPCAWGQPQCPQSIMYRR
101111121131141151161171181191
FLRPRYRVAYKTVTDMEWRCCQGYGGDDCAESPAPALGPASSTPRPLAQPARPNLSGSSAGSPLSGLGGEGPGESEKVQQLEEQVQSLTKELQGLRGVLQ
201211221231241251261271281291
GLSGRLAEDVQRAVETAFNGRQQPADAAARPGVHETLNEIQHQLQLLDTRVSTHDQELGHLNNHHGGSSSSGGSRAPAPASAPPGPSEELLRQLEQRLQE
301311321331341351361371381391
SCSVCLAGLDGFRRQQQEDRERLRAMEKLLASVEERQRHLAGLAVGRRPPQECCSPELGRRLAELERRLDVVAGSVTVLSGRRGTELGGAAGQGGHPPGY
401411421431441451461471481491
TSLASRLSRLEDRFNSTLGPSEEQEESWPGAPGGLSHWLPAARGRLEQLGGLLANVSGELGGRLDLLEEQVAGAMQACGQLCSGAPGEQDSQVSEILSAL
501511521531541551561571581591
ERRVLDSEGQLRLVGSGLHTVEAAGEARQATLEGLQEVVGRLQDRVDAQDETAAEFTLRLNLTAARLGQLEGLLQAHGDEGCGACGGVQEELGRLRDGVE
601611621631641651661671681691
RCSCPLLPPRGPGAGPGVGGPSRGPLDGFSVFGGSSGSALQALQGELSEVILSFSSLNDSLNELQTTVEGQGADLADLGATKDRIISEINRLQQEATEHA
701711721731741751761771781791
TESEERFRGLEEGQAQAGQCPSLEGRLGRLEGVCERLDTVAGGLQGLREGLSRHVAGLWAGLRETNTTSQMQAALLEKLVGGQAGLGRRLGALNSSLQLL
801811821831841851861871881891
EDRLHQLSLKDLTGPAGEAGPPGPPGLQGPPGPAGPPGSPGKDGQEGPIGPPGPQGEQGVEGAPAAPVPQVAFSAALSLPRSEPGTVPFDRVLLNDGGYY
901911921931941951961971981991
DPETGVFTAPLAGRYLLSAVLTGHRHEKVEAVLSRSNQGVARVDSGGYEPEGLENKPVAESQPSPGTLGVFSLILPLQAGDTVCVDLVMGQLAHSEEPLT
10011011
IFSGALLYGDPELEHA

Reference

ID Publication
13Yang W, Laeyendecker O, Wendel SK, Zhang B, Sun S, Zhou J-Y, Ao M, Moore RD, Jackson JB, Zhang H: Glycoproteomic Study Reveals Altered Plasma Proteins Associated with HIV Elite Suppressors. Theranostics 2014, 4:1153.
14Liu Y, Chen J, Sethi A, Li QK, Chen L, Collins B, Gillet LC, Wollscheid B, Zhang H, Aebersold R: Glycoproteomic analysis of prostate cancer tissues by SWATH mass spectrometry discovers N-acylethanolamine acid amidase and protein tyrosine kinase 7 as signatures for tumor aggressiveness. Molecular & Cellular Proteomics 2014, 13:1753-1768.
22Nicastri A, Gaspari M, Sacco R, Elia L, Gabriele C, Romano R, Rizzuto A, Cuda G: N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue. Journal of Proteome Research 2014, 13:4932-4941.
32Zhang Z, Sun Z, Zhu J, Liu J, Huang G, Ye M, Zou H: High-Throughput Determination of the Site-Specific N-Sialoglycan Occupancy Rates by Differential Oxidation of Glycoproteins Followed with Quantitative Glycoproteomics Analysis. Analytical Chemistry 2014, 86:9830-9837.
33Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.
34Sun S, Zhang B, Aiyetan P, Zhou J-Y, Shah P, Yang W, Levine DA, Zhang Z, Chan DW, Zhang H: Analysis of N-glycoproteins using Genomic N-glycosite Prediction. Journal of Proteome Research 2013, 12:5609-5615.
48Danzer C, Eckhardt K, Schmidt A, Fankhauser N, Ribrioux S, Wollscheid B, Mueller L, Schiess R, Zuellig R, Lehmann R, et al: Comprehensive Description of the N-Glycoproteome of Mouse Pancreatic beta-Cells and Human Islets. Journal of Proteome Research 2012, 11:1598-1608.
54Tian Y, Yao Z, Roden R, Zhang H: Identification of glycoproteins associated with different histological subtypes of ovarian tumors using quantitative glycoproteomics. Proteomics 2011, 11:4677-4687.
55Tian Y, Bova GS, Zhang H: Quantitative glycoproteomic analysis of optimal cutting temperature-embedded frozen tissues identifying glycoproteins associated with aggressive prostate cancer. Analytical chemistry 2011, 83:7013-7019.
62Arcinas A, Yen T-Y, Kebebew E, Macher BA: Cell Surface and Secreted Protein Profiles of Human Thyroid Cancer Cell Lines Reveal Distinct Glycoprotein Patterns. Journal of Proteome Research 2009, 8:3958-3968.
64Chen R, Jiang X, Sun D, Han G, Wang F, Ye M, Wang L, Zou H: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. J Proteome Res 2009, 8:651-661.
65Goo YA, Lilu AY, Ryu S, Shaffer SA, Malmstrom L, Page L, Nguyen LT, Doneanu CE, Goodlett DR: Identification of Secreted Glycoproteins of Human Prostate and Bladder Stromal Cells by Comparative Quantitative Proteomics. Prostate 2009, 69:49-61.
74Lewandrowski U, Zahedi RP, Moebius J, Walter U, Sickmann A: Enhanced N-glycosylation site analysis of Sialoglycopeptides by strong cation exchange prefractionation applied to platelet plasma membranes. Molecular & Cellular Proteomics 2007, 6:1933-1941.