Detail

UniProtKB-Q9Y6N6


Protein	Laminin subunit gamma-3
Gene	LAMC3
Status	Reviewed
Source	Breast cancer xenografts; Colorectal tumor; Hela cell line (cervical cancer); LNCap/PC3 cell lines (Prostate cancer); Liver; Ovarian tumor; Prostate; Prostate tumor; Serum; Urine
Years	2007-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
87	HHnASYLTDFHSQDE	2014(33);
119	nITIR	2014(33);
119	nITLR	2014(33);
119	nLTIR	2014(33);
119	nLTLR	2014(33);
119	VnITLR	2007(33); 2014(unpublished);2007(unpublished);2007;
119	VnLTIR	2007(unpublished);
119	VnLTLR	2007(22); 2014(2); 2015(12); 2015(unpublished);2015(unpublished);2015;2015;2007;2007;
328	GTAEAAHECLPCnCSGR	2014(33);
631	LLAnLTSLR	2014(14); 2014(33); 2015(unpublished);
837	CLHnTTGDHCEHCQEGFYGSALAPR	2014(33);
980	nGTCVCRPGFE	2014(33);
1185	ALLASnTSYALLWNLLEGR	2014(33);
1506	LGSLDTHQAPAQALnETQWALER	2014(33); 2015(unpublished);

Sequence

1	11	21	31	41	51	61	71	81	91
MAAAALLLGL	ALLAPRAAGA	GMGACYDGAG	RPQRCLPVFE	NAAFGRLAQA	SHTCGSPPED	FCPHVGAAGA	GAHCQRCDAA	DPQRHHNASY	LTDFHSQDES
101	111	121	131	141	151	161	171	181	191
TWWQSPSMAF	GVQYPTSVNI	TLRLGKAYEI	TYVRLKFHTS	RPESFAIYKR	SRADGPWEPY	QFYSASCQKT	YGRPEGQYLR	PGEDERVAFC	TSEFSDISPL
201	211	221	231	241	251	261	271	281	291
SGGNVAFSTL	EGRPSAYNFE	ESPGLQEWVT	STELLISLDR	LNTFGDDIFK	DPKVLQSYYY	AVSDFSVGGR	CKCNGHASEC	GPDVAGQLAC	RCQHNTTGTD
301	311	321	331	341	351	361	371	381	391
CERCLPFFQD	RPWARGTAEA	AHECLPCNCS	GRSEECTFDR	ELFRSTGHGG	RCHHCRDHTA	GPHCERCQEN	FYHWDPRMPC	QPCDCQSAGS	LHLQCDDTGT
401	411	421	431	441	451	461	471	481	491
CACKPTVTGW	KCDRCLPGFH	SLSEGGCRPC	TCNPAGSLDT	CDPRSGRCPC	KENVEGNLCD	RCRPGTFNLQ	PHNPAGCSSC	FCYGHSKVCA	STAQFQVHHI
501	511	521	531	541	551	561	571	581	591
LSDFHQGAEG	WWARSVGGSE	HPPQWSPNGV	LLSPEDEEEL	TAPEKFLGDQ	RFSYGQPLIL	TFRVPPGDSP	LPVQLRLEGT	GLALSLRHSS	LSGPQDAGHP
601	611	621	631	641	651	661	671	681	691
REVELRFHLQ	ETSEDVAPPL	PPFHFQRLLA	NLTSLRLRVS	PGPSPAGPVF	LTEVRLTSAR	PGLSPPASWV	EICSCPTGYT	GQFCESCAPG	YKREMPQGGP
701	711	721	731	741	751	761	771	781	791
YASCVPCTCN	QHGTCDPNTG	ICVCSHHTEG	PSCERCLPGF	YGNPFAGQAD	DCQPCPCPGQ	SACTTIPESR	EVVCTHCPPG	QRGRRCEVCD	DGFFGDPLGL
801	811	821	831	841	851	861	871	881	891
FGHPQPCHQC	QCSGNVDPNA	VGNCDPLSGH	CLRCLHNTTG	DHCEHCQEGF	YGSALAPRPA	DKCMPCSCHP	QGSVSEQMPC	DPVTGQCSCL	PHVTARDCSR
901	911	921	931	941	951	961	971	981	991
CYPGFFDLQP	GRGCRSCKCH	PLGSQEDQCH	PKTGQCTCRP	GVTGQACDRC	QLGFFGFSIK	GCRACRCSPL	GAASAQCHEN	GTCVCRPGFE	GYKCDRCHDN
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
FFLTADGTHC	QQCPSCYALV	KEEAAKLKAR	LTLTEGWLQG	SDCGSPWGPL	DILLGEAPRG	DVYQGHHLLP	GAREAFLEQM	MSLEGAVKAA	REQLQRLNKG
1101	1111	1121	1131	1141	1151	1161	1171	1181	1191
ARCAQAGSQK	TCTQLADLEA	VLESSEEEIL	HAAAILASLE	IPQEGPSQPT	KWSHLATEAR	ALARSHRDTA	TKIAATAWRA	LLASNTSYAL	LWNLLEGRVA
1201	1211	1221	1231	1241	1251	1261	1271	1281	1291
LETQRDLEDR	YQEVQAAQKA	LRTAVAEVLP	EAESVLATVQ	QVGADTAPYL	ALLASPGALP	QKSRAEDLGL	KAKALEKTVA	SWQHMATEAA	RTLQTAAQAT
1301	1311	1321	1331	1341	1351	1361	1371	1381	1391
LRQTEPLTKL	HQEARAALTQ	ASSSVQAATV	TVMGARTLLA	DLEGMKLQFP	RPKDQAALQR	KADSVSDRLL	ADTRKKTKQA	ERMLGNAAPL	SSSAKKKGRE
1401	1411	1421	1431	1441	1451	1461	1471	1481	1491
AEVLAKDSAK	LAKALLRERK	QAHRRASRLT	SQTQATLQQA	SQQVLASEAR	RQELEEAERV	GAGLSEMEQQ	IRESRISLEK	DIETLSELLA	RLGSLDTHQA
1501	1511	1521	1531	1541	1551	1561	1571
PAQALNETQW	ALERLRLQLG	SPGSLQRKLS	LLEQESQQQE	LQIQGFESDL	AEIRADKQNL	EAILHSLPEN	CASWQ

Reference

ID	Publication
2	Shah P, Wang X, Yang W, Eshghi ST, Sun S, Hoti N, Chen L, Yang S, Pasay J, Rubin A: Integrated Proteomic and Glycoproteomic Analyses of Prostate Cancer Cells Reveal Glycoprotein Alteration in Protein Abundance and Glycosylation. Molecular & Cellular Proteomics 2015, 14:2753-2763.
12	Weng Y, Sui Z, Jiang H, Shan Y, Chen L, Zhang S, Zhang L, Zhang Y: Releasing N-glycan from Peptide N-terminus by N-terminal Succinylation Assisted Enzymatic Deglycosylation. Scientific Reports 2015, 5.
14	Liu Y, Chen J, Sethi A, Li QK, Chen L, Collins B, Gillet LC, Wollscheid B, Zhang H, Aebersold R: Glycoproteomic analysis of prostate cancer tissues by SWATH mass spectrometry discovers N-acylethanolamine acid amidase and protein tyrosine kinase 7 as signatures for tumor aggressiveness. Molecular & Cellular Proteomics 2014, 13:1753-1768.
22	Nicastri A, Gaspari M, Sacco R, Elia L, Gabriele C, Romano R, Rizzuto A, Cuda G: N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue. Journal of Proteome Research 2014, 13:4932-4941.
33	Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.